Protein Alignment Axn and Axn

DIOPT Version :10

• Sequence 1: NP_733336.1
• Gene: Axn / 43565
• FlyBaseID: FBgn0026597
• Length: 745
• Species: Drosophila melanogaster
• Sequence 2: XP_320914.5
• Gene: Axn / 1281346
• VectorBaseID: AGAMI1_004048
• Length: 777
• Species: Anopheles gambiae
• Alignment Length: 811
• Identity: 387/811 - (47%)
• Similarity: 498/811 - (61%)
• Gaps: 118/811 - (14%)

  Fly     9 RKHDDNECSGPRPPVPGEESRVKKMTE-GVADTSKNSS-PSYLNWARTLNHLLEDRDGVELFKKY 71
            :|.||...||||||||||||| :|||| ..:|.:::.| |:|:.||:.|.:||||.||.||||:|
Mosquito    11 QKFDDFHSSGPRPPVPGEESR-RKMTETSHSDRTRDGSPPAYVRWAQKLAYLLEDGDGAELFKRY 74

  Fly    72 VEEEAPAYNDHLNFYFACEGLKQQTDPEKIKQIIGAIY-RFLRK----SQLSISDDLRAQIKAIK 131
            ||.|....::.|.|||||||||||||.:|:.|:||||| |||:|    |:|.:::.||..|||..
Mosquito    75 VELEGEEPSNRLKFYFACEGLKQQTDADKVTQLIGAIYRRFLKKAQPGSELYVNESLRNFIKAGL 139

  Fly   132 TNPEIPLSPHIFDPMQRHVEVTIRDNIYPTFLCSEMYILYIQQMSAQQERCTSSGATGSGS---- 192
            .| |:.|:|.|||.||..|...|.:..||.||.|::|:.|:|.|   |...:||...||||
Mosquito   140 KN-ELELTPDIFDQMQADVANIIAETTYPHFLQSDLYLQYVQNM---QSSSSSSSVIGSGSNCSL 200

  Fly   193 ----AGSSGSGGSSLAGACALPPTTASGKQQLPQLVPPGAFINLPVSSVSGPPAGTCSASGSVYG 253
                :|:..:||    |..|.|.::.:|                 |:|..|...|..:...:..|
Mosquito   201 VAAASGAPSAGG----GGGAAPGSSTAG-----------------VASQQGGGGGAAAGGSAGAG 244

  Fly   254 PSTSASSSGSISATDTLPRSSTLPTLHEDSVLSLCDDFEKVQMQEGGG------SLGSGSVGAGA 312
            .|.|.:||.|.|.. .|..:|.|||:|||:.|:..|..|::....|.|      .:|...|.|..
Mosquito   245 ASCSLTSSSSTSEL-FLHSTSALPTVHEDAELANADSIEQLYGATGPGLDSHMALVGPPLVPAAT 308

  Fly   313 RAPD-YPIRLTRDLLIATQKRRLEIRPPGAHGY-VYNPSTTNTSYVPNSRVDSERASVSSGGRTD 375
            .:|. .|:.||:|.|:||||||||:||||..|| ||   |...||.|.||.|||.||:|| ||||
Mosquito   309 ASPSKVPMTLTKDALMATQKRRLEMRPPGPRGYSVY---TAYASYNPVSRRDSELASLSS-GRTD 369

  Fly   376 SDTMSISSCSMDGRPYIQRR-----HSSTESKAIRQSAMANKETNTFQVIPRTQRLHSNEHRPLK 435
            |||||:||.|.||||:.||:     |||.|.:.:|::|:.|:|.:||.:||||.| |:.:..|
Mosquito   370 SDTMSLSSISTDGRPHSQRKHHHHHHSSIERRMMRENALTNEEVDTFAIIPRTHR-HTQKQPP-- 431

  Fly   436 EEELVSLLIPKLEEVKRKRDLEERARERNPGAALLTNERSSASDRAFAEAIREKFALDEDNDQDI 500
            ..|...:||.|||.|.|:::.:|...::...|.|  ::||  .::..|:|||:|..:|:||||||
Mosquito   432 PMEFAKILINKLECVAREQEKDEVLCKKMQEAEL--SDRS--QNKVLADAIRQKLQVDDDNDQDI 492

  Fly   501 LDQHVSRVWKDQTPHRSPGTMSPCPPIPSRRRTATHDSGMVSDGAMSLSGHSMKHSKSMPD-H-- 562
            |||||||||.|.||.|||||||||||.....|:..|:..... ||.|    ||:||||||: |
Mosquito   493 LDQHVSRVWSDLTPSRSPGTMSPCPPNMIGSRSRRHELASFG-GAQS----SMRHSKSMPEGHPL 552

  Fly   563 ------------SSCSRKLTNKWPSMNTDSGISMFSADTVTKYKDASSRS------GSS------ 603
                        ||.||||.|||||:|||||||:||.||:||:..:...|      |||
Mosquito   553 MGPPMQPMTMQMSSGSRKLANKWPSVNTDSGISLFSTDTLTKHSSSGGGSRGELSLGSSSRPLSR 617

  Fly   604 -------TASKLEEAKRRLEDEPRRSRRYAQP----PMQHLSQQPLASFSSSSSGGSISLP--HQ 655
                   ||:.|:|:.||||||.|||:||..|    .:|.:...|:.|.:||.|.|| |||  ..
Mosquito   618 TMHSDMHTATLLQESSRRLEDETRRSKRYQYPQQASAIQSMPLPPVPSMTSSGSFGS-SLPPAMP 681

  Fly   656 PPPLPAKPPE-----TIVVFSFCEEPVPYRIKIPGTQ-PTLRQFKDYLPRRGHFRFFFKTHCEDP 714
            |||:||||.:     ||||:|||:|.||||||||||| |||:|||||||::|::||||||.|||.
Mosquito   682 PPPIPAKPSQAPNEFTIVVYSFCDEEVPYRIKIPGTQPPTLKQFKDYLPKKGNYRFFFKTRCEDL 746

  Fly   715 DSPVIQEEIVNDSDILPLFGDKAMGLVKPSD 745
            |:||||||:.:||:.||||..|.||.||||:
Mosquito   747 DNPVIQEEVNSDSEPLPLFEGKVMGTVKPSE 777

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Axn	NP_733336.1	RGS	55..170	CDD:470619	64/119 (54%)
		Axin_b-cat_bind	495..530	CDD:462616	29/34 (85%)
		DIX	665..741	CDD:459936	55/81 (68%)
Axn	XP_320914.5	None