Protein Alignment Axn and LOC1273552

DIOPT Version :10

• Sequence 1: NP_733336.1
• Gene: Axn / 43565
• FlyBaseID: FBgn0026597
• Length: 745
• Species: Drosophila melanogaster
• Sequence 2: XP_061501062.1
• Gene: LOC1273552 / 1273552
• VectorBaseID: AGAMI1_003107
• Length: 2323
• Species: Anopheles gambiae
• Alignment Length: 892
• Identity: 178/892 - (19%)
• Similarity: 294/892 - (32%)
• Gaps: 315/892 - (35%)

  Fly    50 NWARTLNHLLEDRDGVELFKKYVEEEAPAYNDHLNFYFACEGLKQQTDPEKIKQIIGAIYRFLRK 114
            :|..:...||||..|:..|.:::::|..|.|  :.|:.|||..:|.|:.|:..:...||:....:
Mosquito  1147 SWGTSFEKLLEDAAGLHTFSEFLKKEFSAEN--IYFWTACERYRQLTEREERAREAQAIFARHLE 1209

  Fly   115 SQLS--ISDDLRAQIKAIKTNPEIPLSPHIFDPMQRHVEVTIRDNIYPTFLCSEMYILYIQQMSA 177
            |..|  ::.|..|:..|::..|:  ..|.:|...|:.:...::.:.|..|:.|::|.:
Mosquito  1210 SGCSEPVNVDSIARNIALENLPQ--AEPTLFAAAQKQIFNLMKFDSYQRFIKSDLYRV------- 1265

  Fly   178 QQERCTSSGATGSGSAGSSGSGGSSLAGACALPPTTASGKQQLPQLVPPGAFINLPVSSVSGPPA 242
                |..:...|.|                 ||   ..|:|..|.|......:
Mosquito  1266 ----CQEAEGKGQG-----------------LP---YPGEQLDPMLRTSATML------------ 1294

  Fly   243 GTCSASGSVYGPSTSASSS---GSISATDTLPRSSTLPTLHEDSVLSL----CDDFEKVQMQEGG 300
               :|||:    .|:||.:   .|:|..:...|.|.||...:....|.    .|..:|...::||
Mosquito  1295 ---TASGT----GTAASITKLKKSLSNAEDRRRKSLLPWHRKTRCKSKDRGDSDTSKKDSKEKGG 1352

  Fly   301 GSLG-------SGSVGAGARAPDYPIRL-----TRDL---------------------------- 325
            ||.|       ||:...|..:....::|     |.|:
Mosquito  1353 GSGGGGGGEKASGTTTTGGGSSSNTLKLLSTNSTSDIHSSRSSLASFDAAIGGKSCDPDDSRNTL 1417

  Fly   326 -----------LIATQ---------KRRLEIRPPGAHGYVYNPSTTNTSYVPNSR--VDSERASV 368
                       ::.|:         :|.||.|     |.|||   ...:::..|.  :|.:..||
Mosquito  1418 CRVILSNGATTVVQTRSNETIKELVERLLEKR-----GIVYN---AYEAFLAGSTKPLDLDGPSV 1474

  Fly   369 SSGGR-TDSDTMSISSCSMDGRPYIQRRHSSTESKAIRQSA--------MANKETNTFQVI---- 420
            |..|: .:.|...:...::..|..|     |.:|||.:..|        ..|.|.:..:|:
Mosquito  1475 SLAGKEVNIDQRVVFKLNLPNRKMI-----SVKSKAAKPLADVLRPILHKYNYELDEMKVVVHST 1534

  Fly   421 ------------------------PRTQRLHSNEHRPL-------------------KEEELVSL 442
                                    ..|..:|....|||                   ::::...|
Mosquito  1535 VDVCLDMTQPVTTVDGLCLYIRSANETPNVHPELGRPLAGARPVINTATHQQIVHHFQQQQQQQL 1599

  Fly   443 LIPKLEEVKRKRDLEERARERN--------PGAALLTNERS----------SAS--------DRA 481
            |  :|:...:.....::.::..        |..|:.||.:|          ||:        .::
Mosquito  1600 L--QLQNGPQGSAAGQQQQQHTFAVPSALPPSYAVATNSKSQQLLGNGTAASATCNNNTVNQTQS 1662

  Fly   482 FAEAIREKFALDEDNDQ---------------DILDQHVSRVWKD------------QTPHRSPG 519
            .|:...|:.:.|:...|               :.||:..::|:.:            ....:.||
Mosquito  1663 RAKEQSEQQSKDDQQQQQQAGVGAGTRGQQELNSLDEITNKVFDELRNGKTAFGGVVTAVGKGPG 1727

  Fly   520 TMS-PC-PPIPSRRRTATHDSGMVSDGAMSLSGHSMKHSKSMPDHSSCSRKLTNKWPSMNTDSGI 582
            |:. .| ....|.||......|  |:.|.|.||...|..|       ||       ...:.|.|.
Mosquito  1728 TVDVDCASDTSSTRRDRFRRRG--SNAAPSESGRGAKSKK-------CS-------TGGSEDGGE 1776

  Fly   583 SM----FSADTVTKYKDASSRSGSSTASK----LEEAKR----RLEDEPRRSRRYAQPPMQHLSQ 635
            |:    .....:.|.| |..:....|.|:    ||..||    ||||:......:..|  ..|..
Mosquito  1777 SVNNLGIKKPIIAKLK-AGVKLQIPTRSQNDELLEGLKRAQRSRLEDQRGTEINFELP--DFLKD 1838

  Fly   636 QPLASFSS---SSSGGSISLPHQPPPLPAKPPETIVVFSFCEEPVPYRIKIPGTQPT-------L 690
            :...|.||   |||.|||.......|..|..|..:.      ...|.| :...|.||       |
Mosquito  1839 KENFSTSSAAVSSSAGSIGASAAAAPSSAAGPSKLT------RSKPAR-RSEATTPTAEFVGGSL 1896

  Fly   691 RQFKDYLP--------RRGHFRFFFKTHCEDPDSPVIQEEIVNDSDI 729
            :|.....|        ::|      :.:...|.|||  ...|:||.:
Mosquito  1897 QQINKPQPAPRLSITGQQG------RQNLSGPGSPV--HAAVSDSHL 1935

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Axn	NP_733336.1	RGS	55..170	CDD:470619	31/116 (27%)
		Axin_b-cat_bind	495..530	CDD:462616	8/63 (13%)
		DIX	665..741	CDD:459936	16/80 (20%)
LOC1273552	XP_061501062.1	None