Protein Alignment Axn and snx13

DIOPT Version :10

• Sequence 1: NP_733336.1
• Gene: Axn / 43565
• FlyBaseID: FBgn0026597
• Length: 745
• Species: Drosophila melanogaster
• Sequence 2: XP_002933347.2
• Gene: snx13 / 100495358
• XenbaseID: XB-GENE-6037458
• Length: 975
• Species: Xenopus tropicalis
• Alignment Length: 518
• Identity: 106/518 - (20%)
• Similarity: 192/518 - (37%)
• Gaps: 159/518 - (30%)

  Fly    27 ESRVKKMTEG-VADTSKNSSPSYLNWAR----TLNHLLEDRDGVELFKKYVEEEAPAYNDHLNFY 86
            |:|::::..| ..||.|.::    |:.:    .|:.:|.|...::.|..::::...  ..||.|:
 Frog   364 ETRIQRLQSGKEIDTVKLAA----NFGKLCTVPLDKILVDNVALQFFMDFMQQTGG--QAHLFFW 422

  Fly    87 FACEGL------------------KQQTDPEK--IKQIIGAIY-RFLRKS---QLSISDDLRAQI 127
            ...||.                  |.||:..|  :|.....:| ::|.:.   ::.|.|.|.|::
 Frog   423 LTVEGYRVTAQQQLEVLHSRQRDGKHQTNQTKGLLKAAAFGVYEQYLSEKASPRVHIDDYLLAKL 487

  Fly   128 KAIKTNPEIPLSPHIFDPMQRHV-EVTIR-DNIYPTFLCSEMYILYIQQMSAQQERCTSSGATGS 190
            :. |.|.|.| :|.|||.:||.| ::.:| :..||:|..:.:||..:.::...:|........|.
 Frog   488 EE-KLNSEDP-TPEIFDDIQRKVYDMMLRNERFYPSFRQNTLYIRMLAELDMLKEPSFKGSDDGD 550

  Fly   191 GSAGSSGSGGSSLAGACALPPTTASGKQQLPQLVPPGAFINLPVSSVSGPPAGTCSASGSVYGPS 255
            |.:.:....||..:   :|...|:|     .:|:...|||:         ..|.|:..|..|...
 Frog   551 GESFNGSPNGSIHS---SLDDLTSS-----DELLQINAFIS---------DTGVCNEHGKTYALY 598

  Fly   256 TSASSSGSISATD----TLPRSSTLPTLHEDSVLSLCDDFEKVQMQEGGGSLGSGSVGAGARAPD 316
            .......::.:.:    |..|.|.....|    :.:.:.||         :|.|.....|.:..:
 Frog   599 AITVQRRALDSMEDMWKTYRRYSDFHDFH----MRITEQFE---------NLASLLKLPGKKTFN 650

  Fly   317 YPIRLTRDLLIATQKRRLEIR---------------PPGAHGYVY-------------------- 346
               .:.::.|   :|||.::.               |..|| ||:
 Frog   651 ---NMDKEFL---EKRRNDLNAYLQLLLNPEIVKASPALAH-YVFDFLENKAYSKGKGDFARKMD 708

  Fly   347 ---NPSTTNTSYVPNSRVDSERASVSSGGRTDSDTMSISSCSMDGRPYIQRRHSSTESKAIRQSA 408
               ||...:...|.|: |.|...|::.|....||.|.    .|..:.....:||..::..:
 Frog   709 TFVNPLRNSMRNVSNA-VKSIPDSLAEGMNKMSDNMG----KMSEKIGQDIKHSFFKAPIL---- 764

  Fly   409 MANKETNTFQVIPRTQRLHSN------------EHRPLKEEELVSLLIPKLEEVKRKRDLEER 459
                       :|:|.....|            ::.||:    |.||:  ::||   .||:||
 Frog   765 -----------VPKTDAFPENYRVSAQLDDNVDDNIPLR----VMLLL--MDEV---FDLKER 807

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Axn	NP_733336.1	RGS	55..170	CDD:470619	36/140 (26%)
		Axin_b-cat_bind	495..530	CDD:462616
		DIX	665..741	CDD:459936
snx13	XP_002933347.2	PXA	119..301	CDD:470618
		RGS_SNX13	396..530	CDD:188674	35/137 (26%)
		PX_SNX13	576..694	CDD:132783	25/146 (17%)
		Nexin_C	810..918	CDD:462541