DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Axn and cep112

DIOPT Version :9

Sequence 1:	NP_733336.1	Gene:	Axn / 43565	FlyBaseID:	FBgn0026597	Length:	745	Species:	Drosophila melanogaster
Sequence 2:	XP_031750093.1	Gene:	cep112 / 100135020	XenbaseID:	XB-GENE-6047288	Length:	943	Species:	Xenopus tropicalis

Alignment Length:	335	Identity:	61/335 - (18%)
Similarity:	121/335 - (36%)	Gaps:	69/335 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   345 VYNPSTTNTSYVPNSRVDSERASVSSGGRTDSDTMS--------ISSCSMDGRPY-----IQRRH 396
            :.||.......:..|.:....:....||..|...:|        :.:.:|:.:.:     :|::|
Frog   202 IENPRYLREKPITLSPIGPRMSQAKVGGSWDEQALSRLQEKEGDMKTKAMEAKFHEEKLRLQQKH 266

  Fly   397 SSTESKAIRQSAMANKETNTFQVIPRTQRLHSNEHRPLKEEELVSLLIPKLEEVKRKRDLEERAR 461
            .:...|.:.:.   |.||...:.:.||::..|        ||.:..|..|::.:.|:..|....:
Frog   267 DADVQKILDRK---NSETEELKELYRTKQAES--------EETIRKLEKKVQALLRESQLIRETK 320

  Fly   462 ERNPGAALLTNERSSAS---------DRAFAEAIREKFALDE---DNDQDILDQHVSRVWKDQTP 514
            |..........|:|..|         ..|.||..:|||.|.:   :|.|.:||...:|:.|.::.
Frog   321 ENQISELKKMCEQSGESLNSEWERKLHSAVAEMEQEKFELQKKHTENIQQLLDDTNARLLKMESE 385

  Fly   515 H--RSPGTMSPCPPI---------------PSRRRTATHDSGM----------VSDGAMSLSGHS 552
            :  :|..|......:               ..|:|.|...:.:          :.|.....|...
Frog   386 YVAQSKATAQTVKELELRVQQLTVEAESSNAQRQRLAQEKAELDKVHQSVSRDLQDAKARCSLLE 450

  Fly   553 MKHSKSMPDHSSCSRKLTNKWPSMNTDSGISMFSADTVTKYKDASSRSGSSTASKLEEAKRRLED 617
            .:..:...||....::|..|     :||.|:..:.....:...|::..| ....|:.:.|::|::
Frog   451 QERERHRQDHERQIQQLKGK-----SDSDINYITQQNALQAVKAANAIG-DLEEKVSQLKQQLQE 509

  Fly   618 EPRRSRRYAQ 627
            ...|..:..|
Frog   510 AEHRMHQRLQ 519

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Axn	NP_733336.1	RGS	55..170	CDD:295367
		Axin_b-cat_bind	494..543	CDD:285982	11/78 (14%)
		DIX	665..739	CDD:279160
cep112	XP_031750093.1	DUF4485	11..94	CDD:405527
cep112	XP_031750093.1	Smc	247..>895	CDD:224117	54/290 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1481971at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010