DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Axn and rgs13

DIOPT Version :9

Sequence 1:	NP_733336.1	Gene:	Axn / 43565	FlyBaseID:	FBgn0026597	Length:	745	Species:	Drosophila melanogaster
Sequence 2:	NP_001082981.1	Gene:	rgs13 / 100037359	ZFINID:	ZDB-GENE-070410-138	Length:	162	Species:	Danio rerio

Alignment Length:	176	Identity:	41/176 - (23%)
Similarity:	83/176 - (47%)	Gaps:	34/176 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 DNECSGPRPPVPGEESRVKK------MTEGV--ADTSKNSSPSYLNWARTLNHLLEDRDGVELFK 69
            :::.:.||        |::|      :||.:  .:||:        |:::|.:||..:.|:..|.
Zfish     4 EDKATNPR--------RLEKWRFRCPLTEKINPGETSQ--------WSQSLENLLRSKYGMATFH 52

  Fly    70 KYVEEEAPAYNDHLNFYFACEGLKQQTDPEKIKQIIGAIY-RFLR---KSQLSISDDLRAQIKAI 130
            .:::.|..  ::::.|:.|||..|:.....::......|: |:::   ..:::|....|   :.|
Zfish    53 TFLKSEFS--DENIEFWLACEDFKKTRSLSRLSSRAKKIFERYIKAEAPKEINIDHVTR---ELI 112

  Fly   131 KTNPEIPLSPHIFDPMQRHVEVTIRDNIYPTFLCSEMYILYIQQMS 176
            |.|...| :...||..||.|...:..:.||.||.|:||...::.:|
Zfish   113 KQNVHAP-TKVCFDEAQRIVFGLMERDSYPRFLRSDMYRSLLESVS 157

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Axn	NP_733336.1	RGS	55..170	CDD:295367	31/118 (26%)
		Axin_b-cat_bind	494..543	CDD:285982
		DIX	665..739	CDD:279160
rgs13	NP_001082981.1	RGS	38..151	CDD:295367	31/118 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3589
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900