DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7920 and ZK1320.9

DIOPT Version :9

Sequence 1:	NP_001263095.1	Gene:	CG7920 / 43562	FlyBaseID:	FBgn0039737	Length:	477	Species:	Drosophila melanogaster
Sequence 2:	NP_496090.1	Gene:	ZK1320.9 / 174526	WormBaseID:	WBGene00014258	Length:	472	Species:	Caenorhabditis elegans

Alignment Length:	484	Identity:	222/484 - (45%)
Similarity:	302/484 - (62%)	Gaps:	22/484 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSKQLARHVGQLNSLLKTAATASSVSAHNNYFTYVRELSHPIARE-----PPIVKPEEAVACVKS 60
            ||.:||:.:.:           |||.:.:.:||....|...:...     |..|..:||:|.|.|
Worm     1 MSLKLAKQLSK-----------SSVISLSRHFTNGPRLPTKLLHAKPGFVPKYVSADEALAMVNS 54

  Fly    61 GDTVFAGGAAATPVALLNAMAKHGKSNNLECVTVCHMHTEGPGEYAKPEYKDHFRSNSFFMGANV 125
            ...::.|..|:.|..||.|:.:...|.||..:.:.|:...|......|:|....::||.|:....
Worm    55 DSDIYVGNHASAPNVLLEALCRRVDSANLNNIRMSHLILSGNCPQFDPKYHGKIQNNSLFICPGN 119

  Fly   126 RKAVADGRGDNVPIFLHEIPNLFYKQIVKPDVSFIHVSPPDNHGYCSLGTSVDCVRAALLNSKLI 190
            ||.|..|..|..||||.|:|:|:....:..|.:.|.|||||..|:|:||..:|...||..::|.|
Worm   120 RKNVNLGAADYTPIFLSEVPSLYTSGTLNVDFALITVSPPDELGFCTLGVDIDTTLAAATSAKKI 184

  Fly   191 VAQINPKMPRTFGDAIIHKSHFDLAIEVTDDLP----QHGTGKISEVEKKIGKLIAENLVKDGAT 251
            :|.:|..||||.|...:|.|||  |..|..|.|    |.|..::||.|::|||:||||||.:|||
Worm   185 IALVNSTMPRTRGHTTVHSSHF--AAMVQTDRPIAFRQSGGEEMSETEQRIGKIIAENLVDNGAT 247

  Fly   252 LQMGIGSIPDAVLAALHNHKDLGIHSEMFANGVVELVRKGCVTNSKKKMHQGRIVGSFLIGDKAL 316
            ||:|||:|||:.|||:..|||||:|:|||::||::|:.:|.:.|.||....|:.|.||..|.|..
Worm   248 LQLGIGAIPDSALAAMKQHKDLGVHTEMFSDGVIDLIDRGIINNQKKAFMPGKTVSSFAFGTKEF 312

  Fly   317 YDFVDNNPFIEMYAIDYVNNTSIVKQQPRMTAINSCIEVDLTGQVCSDSIGPRFYSGFGGQVDFI 381
            |..:||||.......|:.|:..||::..:||:|||.||:|||||:.|||||..|:|||||||||:
Worm   313 YKKIDNNPEFYFAPCDFTNHIDIVRRNSKMTSINSAIEIDLTGQIVSDSIGRNFFSGFGGQVDFM 377

  Fly   382 RGAAEGLDGLGVPIIAMPSTTNKGESKIVPTLKEGAGVVTSRAHVHYVVTEHGIASLFGKNVRQR 446
            ..:..|.||||..|||:||.|.||::||||.|.:|:||||:|||..|:|||||||:|:||::|||
Worm   378 AASPHGFDGLGKAIIALPSRTTKGQTKIVPFLTQGSGVVTTRAHARYIVTEHGIANLWGKSIRQR 442

  Fly   447 MYELIQIADPKHRETLEKQAFERIKVMPS 475
            .||||||:.|..||.|||.||:|.|||||
Worm   443 AYELIQISHPDDREALEKAAFDRFKVMPS 471

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7920	NP_001263095.1	ACH1	43..466	CDD:223504	204/431 (47%)
		SugarP_isomerase	51..217	CDD:294243	61/165 (37%)
		AcetylCoA_hyd_C	312..466	CDD:290075	90/153 (59%)
ZK1320.9	NP_496090.1	ACH1	41..462	CDD:223504	203/422 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160166804
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0427
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1016647at2759
OrthoFinder	1	1.000	-	-		FOG0014364
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR21432
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.850