Protein Alignment CG7912 and Slc26a5

DIOPT Version :10

• Sequence 1: NP_651761.2
• Gene: CG7912 / 43561
• FlyBaseID: FBgn0039736
• Length: 602
• Species: Drosophila melanogaster
• Sequence 2: NP_109652.3
• Gene: Slc26a5 / 80979
• MGIID: 1933154
• Length: 744
• Species: Mus musculus
• Alignment Length: 531
• Identity: 137/531 - (25%)
• Similarity: 254/531 - (47%)
• Gaps: 73/531 - (13%)

  Fly    10 RERL---PNVCGAVSSKARSC--CSMRS----VHRYLPVTDWLPKYQL-NFLAMDVVAGLTVGLT 64
            :|||   ..|..::..|.:..  |:.:.    ::.:||:|.|||.|:. .::..|:|:|::.|:.
Mouse    29 QERLHVKDKVTESIGDKLKQAFTCTPKKIRNIIYMFLPITKWLPAYKFKEYVLGDLVSGISTGVL 93

  Fly    65 AVPQAIAYGAVANLPPAYGLYSAFMGGFVYILLGTCKDITVGPTAIMALMVQPY----------- 118
            .:||.:|:..:|.:||.:||||:|....:|...||.:.|::||.|:::||:...
Mouse    94 QLPQGLAFAMLAAVPPVFGLYSSFYPVIMYCFFGTSRHISIGPFAVISLMIGGVAVRLVPDDIVI 158

  Fly   119 ------VDGNPA-------YAVLICFLSGCIITLMGLLNLGVLMRFISVPVTTGFTMAAALTIAT 170
                  .:|..|       .|:.:..|||.|...:|:...|.:..:::.|:..|||.|||:.:.|
Mouse   159 PGGVNATNGTEARDALRVKVAMSVTLLSGIIQFCLGVCRFGFVAIYLTEPLVRGFTTAAAVHVFT 223

  Fly   171 GQVNSLFGISSSASGFLNSWIYFFGHITQTRRNDAILGCCTLVLLLLMRQL----KNLTFGFK-S 230
            ..:..|||:.:.....:.|.:|....:.|..:|   |..|:|.:.|::..|    |.....|| .
Mouse   224 SMLKYLFGVKTKRYSGIFSVVYSTVAVLQNVKN---LNVCSLGVGLMVFGLLLGGKEFNERFKEK 285

  Fly   231 VWKYISLARNAVAVLIGILLCYLLKNDGKLPFLVSGSITPGLPPFKLPPFHTEDPETGETISFGG 295
            :...|.|...||.:..||...:.|.....:.  |.|::..||    |||   .:|:|       .
Mouse   286 LPAPIPLEFFAVVMGTGISAGFNLHESYSVD--VVGTLPLGL----LPP---ANPDT-------S 334

  Fly   296 MVSNVGTALVSIPLLSILESIAVAKAFSK--GKIVDASQEMIALGVSNILSSFFSSMPITGSFTR 358
            :...|....::|.::....:|::||..:.  |..||.:||:||||:.|.:.|.|.:..|:.|.:|
Mouse   335 LFHLVYVDAIAIAIVGFSVTISMAKTLANKHGYQVDGNQELIALGICNSIGSLFQTFSISCSLSR 399

  Fly   359 TAINNASGVKTPLGGAVTGALVLMTLAFLTTTFAYIPKATLAAIIIA---AMFFMVEYETIGEIW 420
            :.:...:|.||.|.|.:...::|:.:......|..:|:|.|:||:|.   .||  :::..:...|
Mouse   400 SLVQEGTGGKTQLAGCLASLMILLVILATGFLFESLPQAVLSAIVIVNLKGMF--MQFSDLPFFW 462

  Fly   421 RAKKRDMLPFLVTVLTCVFWTLEYGMVVGIVFNALFLLYKSMKPQFFLTTEKFNGIEVTMADLKG 485
            |..|.::..:|.|.::.:|..|:||::..::...|.::|::..|.:.:..:        :.|...
Mouse   463 RTSKIELTIWLTTFVSSLFLGLDYGLITAVIIALLTVIYRTQSPSYKVLGQ--------LPDTDV 519

  Fly   486 SVDYAAAEYLK 496
            .:|..|.|.:|
Mouse   520 YIDIDAYEEVK 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7912	NP_651761.2	SUL1	45..543	CDD:440424	125/487 (26%)
Slc26a5	NP_109652.3	PRK11660	66..709	CDD:481320	130/494 (26%)
		Involved in motor function. /evidence=ECO:0000250|UniProtKB:Q9JKQ2	158..168		0/9 (0%)
		Extended region for STAS domain. /evidence=ECO:0000250|UniProtKB:Q9EPH0	505..718		6/34 (18%)
		STAS_anti-anti-sigma_factors	589..683	CDD:132914
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	720..744