Protein Alignment CG7912 and Slc26a4

DIOPT Version :10

• Sequence 1: NP_651761.2
• Gene: CG7912 / 43561
• FlyBaseID: FBgn0039736
• Length: 602
• Species: Drosophila melanogaster
• Sequence 2: NP_062087.1
• Gene: Slc26a4 / 29440
• RGDID: 3293
• Length: 780
• Species: Rattus norvegicus
• Alignment Length: 599
• Identity: 159/599 - (26%)
• Similarity: 272/599 - (45%)
• Gaps: 108/599 - (18%)

  Fly    12 RLPNVCGAVSSKARSC-CSMR----SVHRYLPVTDWLPKYQL-NFLAMDVVAGLTVGLTAVPQAI 70
            |||.......|.|||| ||.:    ::...||:.||||||:: .:|..|:::|::.||....|.:
  Rat    39 RLPERRTLRDSLARSCSCSRKRAFGALKALLPILDWLPKYRVKEWLLSDIISGVSTGLVGTLQGM 103

  Fly    71 AYGAVANLPPAYGLYSAFMGGFVYILLGTCKDITVGPTAIMALMVQPYV------------DGN- 122
            ||..:|.:|..|||||||.....|.:.||.:.|:|||..:::|||...|            .||
  Rat   104 AYALLAAVPVQYGLYSAFFPILTYFVFGTSRHISVGPFPVVSLMVGSVVLSMAPDDHFLVPSGNG 168

  Fly   123 -------------PAYAVLIC----FLSGCIITLMGLLNLGVLMRFISVPVTTGFTMAAALTIAT 170
                         .|..||:.    .|.|.|..:.|.|.:|.::|:::.|:..|||.|||..:..
  Rat   169 STLNTTTLDTGTRDAARVLLASTLTLLVGIIQLVFGGLQIGFIVRYLADPLVGGFTTAAAFQVLV 233

  Fly   171 GQVNSLFGISSSASGFLNSWIY----FFGHITQTRRNDAILGCCTLVLLLLMRQLKNLTFGFKSV 231
            .|:..:..:|:.....:.|.||    .|.:|..|...|.|.|..|:::.:.:::| |..|..|..
  Rat   234 SQLKIVLNVSTKNYNGVLSIIYTLIEIFQNIGDTNIADFIAGLLTIIVCMAVKEL-NDRFKHKIP 297

  Fly   232 WKYISLARNAVAVLIGILLCYLLK-----NDGKLPFLVSGSITPGLPPFKLPPFHTEDPETGETI 291
               :.:....:..:|...:.|...     |.|.:..:.||.:.|.||..
  Rat   298 ---VPIPIEVIVTIIATAISYGANLEANYNAGIVKSIPSGFLPPVLPSV---------------- 343

  Fly   292 SFGGMVSNVGTALVSIPLLSILESIAVAKAFS--KGKIVDASQEMIALGVSNILSSFFSSMPITG 354
               |:.|::..|..||.:::...:::|.|.::  ...|:|.:||.||.|:||:.|.|||....|.
  Rat   344 ---GLFSDMLAASFSIAVVAYAIAVSVGKVYATKHDYIIDGNQEFIAFGISNVFSGFFSCFVATT 405

  Fly   355 SFTRTAINNASGVKTPLGGAVTGALVLMTLAFLTTTFAYIPKATLAAIIIA---AMFFMVEYETI 416
            :.:|||:..::|.||.:.|.::..:|::.:..|......:.|:.|||::||   .||..|  ..:
  Rat   406 ALSRTAVQESTGGKTQVAGLISAVIVMVAIVALGKLLEPLQKSVLAAVVIANLKGMFMQV--CDV 468

  Fly   417 GEIWRAKKRDMLPFLVTVLTCVFWTLEYGMVVGIVFNALFLLYKSMKPQFFLTTEKFNGIEVTMA 481
            ..:|:..|.|.:.::.|.:..:...|:.|::.|::|..|.::.:...|       .:||:
  Rat   469 PRLWKQNKTDAVIWVFTCIMSIILGLDLGLLAGLLFGLLTVVLRVQFP-------SWNGL----- 521

  Fly   482 DLKGSVDYAAAEYLKMSLVSHVTQRNSEG------SAPTTLVVIKGHEIASIDTTVALN------ 534
               |||  .:.:..| |:..:......||      |:|.....:.|.: ..:.:||..:
  Rat   522 ---GSV--PSTDIYK-SITHYKNLEEPEGVKILRFSSPIFYGNVDGFK-KCVKSTVGFDAIRVYN 579

  Fly   535 --LKSLREDLALLK 546
              ||:||....|:|
  Rat   580 KRLKALRRIQKLIK 593

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7912	NP_651761.2	SUL1	45..543	CDD:440424	141/556 (25%)
Slc26a4	NP_062087.1	PRK11660	70..725	CDD:481320	148/568 (26%)