Protein Alignment CG7912 and SLC26A3

DIOPT Version :10

• Sequence 1: NP_651761.2
• Gene: CG7912 / 43561
• FlyBaseID: FBgn0039736
• Length: 602
• Species: Drosophila melanogaster
• Sequence 2: NP_000102.1
• Gene: SLC26A3 / 1811
• HGNCID: 3018
• Length: 764
• Species: Homo sapiens
• Alignment Length: 618
• Identity: 141/618 - (22%)
• Similarity: 256/618 - (41%)
• Gaps: 138/618 - (22%)

  Fly    27 CCS------MRSVHRYLPVTDWLPKYQL-NFLAMDVVAGLTVGLTAVPQAIAYGAVANLPPAYGL 84
            |||      .|.|....|:..|||.|:| .:|..|:|:|::.|:.||.|.:|:..:.::||.|||
Human    42 CCSCSPQKAKRIVLSLFPIASWLPAYRLKEWLLSDIVSGISTGIVAVLQGLAFALLVDIPPVYGL 106

  Fly    85 YSAFMGGFVYILLGTCKDITVGPTAIMALMVQPYVDG---------------------------- 121
            |::|....:|:..||.:.|:|||..|:::||...|.|
Human   107 YASFFPAIIYLFFGTSRHISVGPFPILSMMVGLAVSGAVSKAVPDRNATTLGLPNNSNNSSLLDD 171

  Fly   122 ---NPAYAVLICFLSGCIITLMGLLNLGVLMRFISVPVTTGFTMAAALTIATGQVNSLFGIS--- 180
               ..|.|..:..|||.|....|:|.:|.::.::|..:.:|||.|||:.:...|:..:|.::
Human   172 ERVRVAAAASVTVLSGIIQLAFGILRIGFVVIYLSESLISGFTTAAAVHVLVSQLKFIFQLTVPS 236

  Fly   181 -SSASGFLNSWIYFFGHITQTRRNDAILGCCTLVLLLLMRQLKNLTFGFKSVWKYISLARNAVAV 244
             :............|..|.:|...|.:   ..|::||::..:|.:...||.... :.:....:..
Human   237 HTDPVSIFKVLYSVFSQIEKTNIADLV---TALIVLLVVSIVKEINQRFKDKLP-VPIPIEFIMT 297

  Fly   245 LIGILLCYLLKNDGKLPFLVSGSITPGLPPFKLPPFHTEDPETGETISFGGMVSN-VGTALVSIP 308
            :|...:.|......:....|.|.:.||..|          |.|.:..:|...|.: .|.|:|
Human   298 VIAAGVSYGCDFKNRFKVAVVGDMNPGFQP----------PITPDVETFQNTVGDCFGIAMV--- 349

  Fly   309 LLSILESIAVAKAFSKGKI--------VDASQEMIALGVSNILSSFFSSMPITGSFTRTAINNAS 365
                    |.|.|||...:        :|.:||:||||:.||:...|.....:.:.:|:|:..::
Human   350 --------AFAVAFSVASVYSLKYDYPLDGNQELIALGLGNIVCGVFRGFAGSTALSRSAVQEST 406

  Fly   366 GVKTPLGGAVTGALVLMTLAFLTTTFAYIPKATLAAIIIAAM-FFMVEYETIGEIWRAKKRDMLP 429
            |.||.:.|.:...:||:.:..:....|.:.|:.|||:.:..: ..::::..||.:||..|.|.|.
Human   407 GGKTQIAGLIGAIIVLIVVLAIGFLLAPLQKSVLAALALGNLKGMLMQFAEIGRLWRKDKYDCLI 471

  Fly   430 FLVTVLTCVFWTLEYGMVVGIVFNALFLLYKSMKPQFFLTTEKFNGIEVTMADL------KGSVD 488
            :::|.:..:...|..|:...:.|..|.:::::..|:.           .|:|::      |...|
Human   472 WIMTFIFTIVLGLGLGLAASVAFQLLTIVFRTQFPKC-----------STLANIGRTNIYKNKKD 525

  Fly   489 Y--------------------AAAEYLKMSLVSHVTQRNSEGSAPTTLVVIKGHEIASIDTTVAL 533
            |                    |...:.:..|:..|      |.:|..::..:.
Human   526 YYDMYEPEGVKIFRCPSPIYFANIGFFRRKLIDAV------GFSPLRILRKRN------------ 572

  Fly   534 NLKSLREDLALLKCDMICWNWSIPAAGVICRMD 566
              |:||:...|.|..::    .:...|.||.:|
Human   573 --KALRKIRKLQKQGLL----QVTPKGFICTVD 599

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7912	NP_651761.2	SUL1	45..543	CDD:440424	126/569 (22%)
SLC26A3	NP_000102.1	Sulfate_transp	73..475	CDD:459995	105/426 (25%)
		STAS_SulP_like_sulfate_transporter	526..712	CDD:132913	15/98 (15%)
		PDZ-binding. /evidence=ECO:0000269|PubMed:22627094	761..764