Protein Alignment Nlp and NPM2

DIOPT Version :9

• Sequence 1: NP_001263094.1
• Gene: Nlp / 43560
• FlyBaseID: FBgn0016685
• Length: 152
• Species: Drosophila melanogaster
• Sequence 2: XP_011542662.1
• Gene: NPM2 / 10361
• HGNCID: 7930
• Length: 289
• Species: Homo sapiens
• Alignment Length: 168
• Identity: 51/168 - (30%)
• Similarity: 78/168 - (46%)
• Gaps: 29/168 - (17%)

  Fly     7 YGVTLTAESDSVTWDVDEDYARGQKLVIKQILLGAEAKENEFNVVEVNTP-----KDSVQIPIAV 66
            :|..|:.|..:.|:....:..:..:|::..|.||.:||| |.:.||:..|     |....:.||.
Human    94 HGCELSQERRTWTFRPQLEGKQSCRLLLHTICLGEKAKE-EMHRVEILPPANQEDKKMQPVTIAS 157

  Fly    67 LKAGETRAVNPDVEF----YESKVTFKLIKGSGPVYIHGHN---------IKDDVEVVDMEEDDE 118
            |:|    :|.|.|..    ....|||:|..|||||::.|..         .:::.|..:.||::|
Human   158 LQA----SVLPMVSMVGVQLSPPVTFQLRAGSGPVFLSGQERYEASDLTWEEEEEEEGEEEEEEE 218

  Fly   119 EDDVAEDE----EDEHPKKRAKIENAADGKNAKNNKKK 152
            |||..||.    |::.|.|:.|  .....|.|...|||
Human   219 EDDEDEDADISLEEQSPVKQVK--RLVPQKQASVAKKK 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlp	NP_001263094.1	Nucleoplasmin	6..104	CDD:397268	33/114 (29%)
NPM2	XP_011542662.1	Nucleoplasmin	95..>194	CDD:281111	33/103 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165158348
Domainoid	1	1.000	47	1.000	Domainoid score	I12005
eggNOG	1	0.900	-	-		E1_2C49J
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	58	1.000	Inparanoid score	I5411
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1485080at2759
OrthoFinder	1	1.000	-	-		FOG0000973
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22747
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	9	8.900