Protein Alignment Nph and NPM2

DIOPT Version :9

• Sequence 1: NP_001097975.1
• Gene: Nph / 43559
• FlyBaseID: FBgn0039735
• Length: 156
• Species: Drosophila melanogaster
• Sequence 2: XP_011542662.1
• Gene: NPM2 / 10361
• HGNCID: 7930
• Length: 289
• Species: Homo sapiens
• Alignment Length: 174
• Identity: 48/174 - (27%)
• Similarity: 76/174 - (43%)
• Gaps: 37/174 - (21%)

  Fly     7 YGVTLSEKEAIAQFEVPDVPEEYIVHSHKLIIKQISLGPEAKTGEFNVVQAETNINDDGEKKTLK 71
            :|..||::.....|.    |:.....|.:|::..|.||.:||. |.:.|:.....|.: :||...
Human    94 HGCELSQERRTWTFR----PQLEGKQSCRLLLHTICLGEKAKE-EMHRVEILPPANQE-DKKMQP 152

  Fly    72 IPIAVLKVGETRSLRPNVEFP----NGSVTFKLVQGSGPVHVCG------------KVEMNFGEF 120
            :.||.|:.    |:.|.|...    :..|||:|..|||||.:.|            :.|...||.
Human   153 VTIASLQA----SVLPMVSMVGVQLSPPVTFQLRAGSGPVFLSGQERYEASDLTWEEEEEEEGEE 213

  Fly   121 DDGQIYEEYSDEEEDSELEFDEEA--------APQTNGKSNKKK 156
            ::   .||..||:||:::..:|::        .||......|||
Human   214 EE---EEEEDDEDEDADISLEEQSPVKQVKRLVPQKQASVAKKK 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nph	NP_001097975.1	Nucleoplasmin	6..112	CDD:397268	33/120 (28%)
NPM2	XP_011542662.1	Nucleoplasmin	95..>194	CDD:281111	33/108 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165158349
Domainoid	1	1.000	47	1.000	Domainoid score	I12005
eggNOG	1	0.900	-	-		E1_2C49J
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	58	1.000	Inparanoid score	I5411
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1485080at2759
OrthoFinder	1	1.000	-	-		FOG0000973
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22747
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	9	8.900