| Sequence 1: | NP_733334.1 | Gene: | Tace / 43558 | FlyBaseID: | FBgn0039734 | Length: | 732 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_997080.1 | Gene: | ADAM15 / 8751 | HGNCID: | 193 | Length: | 863 | Species: | Homo sapiens |
| Alignment Length: | 661 | Identity: | 159/661 - (24%) |
|---|---|---|---|
| Similarity: | 246/661 - (37%) | Gaps: | 176/661 - (26%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 62 TIKEVEFTTLGKNFRLILH-----------PHRDVLHSKFRAYAVDADGNETVV--HMDHDSFYS 113
Fly 114 GRVFGELESSVRAHIEDGTMTMSIHLPEETYHIEPSWRHLPEAKKDTMVAYKASDVKVHKNEAGA 178
Fly 179 TPKTCGYI-KEGLELE-DKEH--GDTLDNELHTREKRQSDQYEYTPTKTRCPLLLVAD------Y 233
Fly 234 RFFQEMGGGNTKTTINYLISLIDRVHKIYNDTVWQDRSDQEGFKGMGFVIKKIVVHSEPTRLRGG 298
Fly 299 EAHYNMIREKWDVRNLLEV-------------FSREY-----SHKDFCLAHLFTDLKFEGGILGL 345
Fly 346 AYVGSPRRNSVGGICTPEYFKNGYTLYLNS---GLSSSRNHYGQRVITREADLVTAHEFGHNWGS 407
Fly 408 EHDPDIPEC-SPSASQGGSFLMYTYSVSGYDVNNKKFSPCSLRSIRKVLQAKSGRCFSE------ 465
Fly 466 PEESFCGNLRVEGDEQCDAGLLGTEDN--DSCCDK-NCKLRRNQGAMCSDKNSPCCQNCQFMASG 527
Fly 528 MKCREAQYATCEQEARCTGAHAECPKSPAMADGTTCQERGQ--CRNGKCVPYC-ETQGLQSCMCD 589
Fly 590 IIADACKR----------CCRMSINETCFPVEPPDVLPDGTPCITGFCNKGVCEKTIQDVVERFW 644
Fly 645 DIIE----EIN 651 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Tace | NP_733334.1 | Pep_M12B_propep | 50..162 | CDD:279848 | 24/112 (21%) |
| ZnMc_TACE_like | 223..470 | CDD:239798 | 60/280 (21%) | ||
| Reprolysin_2 | 244..456 | CDD:290307 | 46/233 (20%) | ||
| Disintegrin | 477..552 | CDD:278623 | 32/77 (42%) | ||
| ADAM17_MPD | 576..633 | CDD:271205 | 11/67 (16%) | ||
| ADAM15 | NP_997080.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 22..45 | ||
| Pep_M12B_propep | 62..154 | CDD:279848 | 20/91 (22%) | ||
| Cysteine switch. /evidence=ECO:0000250 | 177..184 | 2/13 (15%) | |||
| Reprolysin | 213..413 | CDD:279729 | 59/271 (22%) | ||
| ZnMc_adamalysin_II_like | 213..411 | CDD:239797 | 59/269 (22%) | ||
| DISIN | 430..504 | CDD:214490 | 34/80 (43%) | ||
| Cell attachment site. /evidence=ECO:0000255|PROSITE-ProRule:PRU00068 | 484..486 | 0/2 (0%) | |||
| ACR | 508..649 | CDD:214743 | 23/110 (21%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 736..863 | ||||
| SH3-binding. /evidence=ECO:0000255 | 815..821 | ||||
| SH3-binding. /evidence=ECO:0000255 | 850..856 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D162519at2759 | |
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R4147 |
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 3 | 2.950 | |||||