Protein Alignment Tace and Tace

DIOPT Version :10

• Sequence 1: NP_733334.1
• Gene: Tace / 43558
• FlyBaseID: FBgn0039734
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: XP_312572.6
• Gene: Tace / 1273579
• VectorBaseID: AGAMI1_013847
• Length: 759
• Species: Anopheles gambiae
• Alignment Length: 749
• Identity: 598/749 - (79%)
• Similarity: 645/749 - (86%)
• Gaps: 33/749 - (4%)

  Fly    13 IISVFFACLFVENCAALQKTLRHYEIFHKDDVVHRVVKRGAKHSTNPFNTIKEVEFTTLGKNFRL 77
            ::.|.||.|.......|.|.|::||..|..|:.||:.|||.|||.:||||||||||..||:.|||
Mosquito    11 VLVVSFAVLIAPLQGQLHKNLKYYETLHAKDLSHRIEKRGTKHSNHPFNTIKEVEFKVLGRKFRL 75

  Fly    78 ILHPHRDVLHSKFRAYAVDADGNETVVHMDHDSFYSGRVFGELESSVRAHIEDGTMTMSIHLPEE 142
            |||||..||||.||||.||.:|:|::||:|..:|:.||||||:||.|.|||:||.||.|:.||:|
Mosquito    76 ILHPHASVLHSNFRAYTVDGNGSESIVHLDRSNFFKGRVFGEMESHVNAHIDDGVMTASVVLPDE 140

  Fly   143 TYHIEPSWRHLPEAKKDTMVAYKASDVKVHKNEAGA------TPKTCGYIKEGLELEDKE----- 196
            ||||||||||||......|:||:.||:|...::..|      .|:||||||||||||.:|
Mosquito   141 TYHIEPSWRHLPHLSDKHMIAYRTSDIKFSWDQVDAISGDLGVPRTCGYIKEGLELEGQEAEEDE 205

  Fly   197 --HGDTLDNEL-------------------HTREKRQSDQYEYTPTKTRCPLLLVADYRFFQEMG 240
              .|||...|.                   .:|.|||:|||||||||||||||||||||||||||
Mosquito   206 EIEGDTERYETDSDPTPETVWHAEDRPESKRSRRKRQADQYEYTPTKTRCPLLLVADYRFFQEMG 270

  Fly   241 GGNTKTTINYLISLIDRVHKIYNDTVWQDRSDQEGFKGMGFVIKKIVVHSEPTRLRGGEAHYNMI 305
            |.|||||||||||||||||||||||:||||||||||||||||||||||||||||:|||||||||:
Mosquito   271 GSNTKTTINYLISLIDRVHKIYNDTIWQDRSDQEGFKGMGFVIKKIVVHSEPTRVRGGEAHYNMV 335

  Fly   306 REKWDVRNLLEVFSREYSHKDFCLAHLFTDLKFEGGILGLAYVGSPRRNSVGGICTPEYFKNGYT 370
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mosquito   336 REKWDVRNLLEVFSREYSHKDFCLAHLFTDLKFEGGILGLAYVGSPRRNSVGGICTPEYFKNGYT 400

  Fly   371 LYLNSGLSSSRNHYGQRVITREADLVTAHEFGHNWGSEHDPDIPECSPSASQGGSFLMYTYSVSG 435
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mosquito   401 LYLNSGLSSSRNHYGQRVITREADLVTAHEFGHNWGSEHDPDIPECSPSASQGGSFLMYTYSVSG 465

  Fly   436 YDVNNKKFSPCSLRSIRKVLQAKSGRCFSEPEESFCGNLRVEGDEQCDAGLLGTEDNDSCCDKNC 500
            ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||:||||||
Mosquito   466 YDVNNKKFSPCSLRSIRKVLQAKSGRCFSEPEESFCGNLRVEGDEQCDAGLLGTEDNDACCDKNC 530

  Fly   501 KLRRNQGAMCSDKNSPCCQNCQFMASGMKCREAQYATCEQEARCTGAHAECPKSPAMADGTTCQE 565
            ||||||||:|||||||||||||:|.:|:||||||||||||||||||.||||||||.|:|||.|||
Mosquito   531 KLRRNQGAVCSDKNSPCCQNCQYMMAGVKCREAQYATCEQEARCTGNHAECPKSPPMSDGTMCQE 595

  Fly   566 RGQCRNGKCVPYCETQGLQSCMCDIIADACKRCCRMSINETCFPVEPPDVLPDGTPCITGFCNKG 630
            |||||||||||||||||||||||||||||||||||.||||||||||||||||||||||.||||||
Mosquito   596 RGQCRNGKCVPYCETQGLQSCMCDIIADACKRCCRQSINETCFPVEPPDVLPDGTPCIQGFCNKG 660

  Fly   631 VCEKTIQDVVERFWDIIEEINVAKTLRFLKDNIVMAVVLVTAVFWIPISCVISYFDRKKLRHEMK 695
            :||||||||||||||||||||:.|.||||:||||||||::||:||||:|||||||||||.:.:.|
Mosquito   661 MCEKTIQDVVERFWDIIEEININKVLRFLRDNIVMAVVMLTALFWIPVSCVISYFDRKKRKEDWK 725

  Fly   696 LIEWSQKLDLIHPSDERRRVIHIRVPRQKISVAR 729
            ..||||||||||||| ||||||||||||||:|||
Mosquito   726 EYEWSQKLDLIHPSD-RRRVIHIRVPRQKITVAR 758

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tace	NP_733334.1	Pep_M12B_propep	44..164	CDD:460254	77/119 (65%)
		ZnMc_TACE_like	223..470	CDD:239798	242/246 (98%)
		Disintegrin	477..552	CDD:459709	67/74 (91%)
		ADAM17_MPD	576..633	CDD:271205	53/56 (95%)
Tace	XP_312572.6	None