DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15525 and Ccdc12

DIOPT Version :9

Sequence 1:	NP_651757.1	Gene:	CG15525 / 43556	FlyBaseID:	FBgn0039732	Length:	161	Species:	Drosophila melanogaster
Sequence 2:	NP_082588.2	Gene:	Ccdc12 / 72654	MGIID:	1919904	Length:	166	Species:	Mus musculus

Alignment Length:	163	Identity:	70/163 - (42%)
Similarity:	98/163 - (60%)	Gaps:	14/163 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 GVGKLTQESLKRKERLQKLREQVQNKG-----------GDAAESIEKLPKPVFRSYKPQNETTDG 61
            |||:|.:|:|:|||||:.|||:...|.           .:..|.:.|......|:|.|::|....
Mouse     7 GVGRLEEEALRRKERLKALREKTGRKDREDGEPQTKQLREEGEEVGKHRGLRLRNYVPEDEDLKR 71

  Fly    62 EILAQEPTGNIESAVEDQLSLLQQPMVIDEIDITNLAPRKPDWDLKRDASKKLERLERRTQKAIA 126
            ..:.|.....:|..|::||...:...||:|:|:.||||||||||||||.:||||:||:|||:|||
Mouse    72 RRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLEKRTQRAIA 136

  Fly   127 ELIRERLKLNQMEDISQAVNVATAHAGESVQED 159
            |||||||| .|.:.::.||:..|..  |:...|
Mouse   137 ELIRERLK-GQEDSLASAVDATTGQ--EACDSD 166

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15525	NP_651757.1	cwf18	11..132	CDD:285510	57/131 (44%)
Ccdc12	NP_082588.2	cwf18	11..143	CDD:369809	58/131 (44%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	21..55		8/33 (24%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	146..166		5/21 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167831434
Domainoid	1	1.000	108	1.000	Domainoid score	I6480
eggNOG	1	0.900	-	-		E1_KOG3407
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H41751
Inparanoid	1	1.050	120	1.000	Inparanoid score	I4768
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52393
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005517
OrthoInspector	1	1.000	-	-		oto95329
orthoMCL	1	0.900	-	-		OOG6_103244
Panther	1	1.100	-	-	LDO	PTHR31551
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R274
SonicParanoid	1	1.000	-	-		X3935
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.790