DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7903 and rbm4.1

DIOPT Version :9

Sequence 1:	NP_651755.2	Gene:	CG7903 / 43554	FlyBaseID:	FBgn0039730	Length:	384	Species:	Drosophila melanogaster
Sequence 2:	NP_955999.1	Gene:	rbm4.1 / 573001	ZFINID:	ZDB-GENE-030131-3902	Length:	419	Species:	Danio rerio

Alignment Length:	330	Identity:	84/330 - (25%)
Similarity:	117/330 - (35%)	Gaps:	96/330 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 TTAKVFVGSL-PRCKPEELRRLFTNYGSVVECDVMNRCAFVHLENTDMAEAAIAALNGTIFKGQP 66
            |:.|..||:: ..|..:|||..|..||.|||||::...||||:|..:.|..||:.|:.|.|:|:.
Zfish    76 TSTKPHVGNISSSCTNQELRAKFEEYGPVVECDIVKDYAFVHMERVEDAMEAISGLDNTAFQGKL 140

  Fly    67 IVVEAGRPKYGPGGGSRGQPGSGDNPGRRPSQVQGGGADKRPHESNTNFKRNFREEVGGRFSNEG 131
            :.|:....:.      |..||.|:..|......:|..:.:.|.:.|.:::             ||
Zfish   141 MSVKLSTSRL------RTAPGMGERTGCYRCGQEGHWSKECPLDQNGSYR-------------EG 186

  Fly   132 PRSSNSSAAKFGPVRNESNYRQQRSAPYSKGPPNNESSNQGQGFRNKFAGGGKFGGSAGNEGRFG 196
            |.|..     |||||.:|                  ..::|:||...|:|...:.||
Zfish   187 PSSEG-----FGPVRFDS------------------GGDRGRGFHRGFSGEPAYAGS-------- 220

  Fly   197 SNRFQQRDNSGPQPGRRNFKNSPTSGY-RGGGNNSDFQGGSSSSGGGGSVNQRAGGGGPGPSHVR 260
                     ..|..|..........|| ||.|..|....|..:..|.|:.|..|...|   |...
Zfish   221 ---------FAPSHGFTRGAGYAVPGYGRGAGFESAMGYGMPAGYGVGADNSMAPVYG---SEAA 273

  Fly   261 QDRRGFALPVEHQQQQMGFGRFGNGPMNSGNRGTNGGNPP-------GGRGFFNG------GGGG 312
            ....|.|.|          |.....|:.         .||       |...|:..      ||..
Zfish   274 YGTSGMAYP----------GALPAYPIR---------RPPYEERDPYGVVDFYEKYRARPYGGSY 319

  Fly   313 FNDRR 317
            |.|||
Zfish   320 FEDRR 324

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7903	NP_651755.2	RRM	<4..168	CDD:223796	46/164 (28%)
CG7903	NP_651755.2	RRM_SF	6..70	CDD:302621	27/64 (42%)
rbm4.1	NP_955999.1	RRM1_RBM4	2..68	CDD:241050
		RRM2_RBM4	78..144	CDD:241051	27/65 (42%)
		ZnF_C2HC	161..176	CDD:197667	2/14 (14%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	322..341		3/3 (100%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	349..371
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	64	1.000	Domainoid score	I10137
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1563362at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	4	3.880