DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7903 and HNRNPC

DIOPT Version :9

Sequence 1:	NP_651755.2	Gene:	CG7903 / 43554	FlyBaseID:	FBgn0039730	Length:	384	Species:	Drosophila melanogaster
Sequence 2:	NP_001070910.1	Gene:	HNRNPC / 3183	HGNCID:	5035	Length:	306	Species:	Homo sapiens

Alignment Length:	180	Identity:	44/180 - (24%)
Similarity:	71/180 - (39%)	Gaps:	49/180 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MNTTAKVFVGSLPR--CKPEELRRLFTNYGSVVECDVMNRCAFVHLENTDMAEAAIAALNGTIFK 63
            ||  ::||:|:|..  .|..::..:|:.||.:|.|.|....|||...|...|.||:|..:|.:..
Human    14 MN--SRVFIGNLNTLVVKKSDVEAIFSKYGKIVGCSVHKGFAFVQYVNERNARAAVAGEDGRMIA 76

  Fly    64 GQPIVVE-AGRPKYGPGGGSRGQPGSGDNPGRRPSQVQGGGADKRPHES---------NTNFKRN 118
            ||.:.:. |..||.     :||:.|.     :|.:....|...:.|..|         :.:|:|:
Human    77 GQVLDINLAAEPKV-----NRGKAGV-----KRSAAEMYGSVTEHPSPSPLLSSSFDLDYDFQRD 131

  Fly   119 F-------------------------REEVGGRFSNEGPRSSNSSAAKFG 143
            :                         |:.|.|..|..|....||.:.:.|
Human   132 YYDRMYSYPARVPPPPPIARAVVPSKRQRVSGNTSRRGKSGFNSKSGQRG 181

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7903	NP_651755.2	RRM	<4..168	CDD:223796	42/177 (24%)
CG7903	NP_651755.2	RRM_SF	6..70	CDD:302621	22/65 (34%)
HNRNPC	NP_001070910.1	RRM_hnRNPC	10..93	CDD:410015	27/85 (32%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	139..190		8/43 (19%)
		Nuclear localization signal. /evidence=ECO:0000255	155..161		1/5 (20%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	221..306
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910