DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7903 and Rbm14

DIOPT Version :9

Sequence 1:	NP_651755.2	Gene:	CG7903 / 43554	FlyBaseID:	FBgn0039730	Length:	384	Species:	Drosophila melanogaster
Sequence 2:	NP_596879.1	Gene:	Rbm14 / 170900	RGDID:	620542	Length:	669	Species:	Rattus norvegicus

Alignment Length:	532	Identity:	120/532 - (22%)
Similarity:	174/532 - (32%)	Gaps:	186/532 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 TAKVFVGSL-PRCKPEELRRLFTNYGSVVECDVMNRCAFVHLENTDMAEAAIAALNGTIFKGQPI 67
            |.|:|||:: ..|..:|||.||...|.|:||||:...||||:|....|:||||.|||...||:.|
  Rat    78 TWKIFVGNVSAACTSQELRSLFERRGRVIECDVVKDYAFVHMEKEADAKAAIAQLNGKEVKGKRI 142

  Fly    68 VVEAGR--PKYGP-----GGGSRGQPGSGDN--PGRRPSQVQGGGADKRPHESNTNFKRNFREEV 123
            .||...  .|.||     .|....:||:||.  ||.       ||     ..:..::::.|....
  Rat   143 NVELSTKGQKKGPALAIQSGDKTKKPGAGDTAFPGT-------GG-----FSATFDYQQAFGNST 195

  Fly   124 GGRFSNEGP--------------RSSNSSAAKFGPVRNE-SNYRQQRS----APYSKGPPNNESS 169
            || |..:..              |.|...|:...|:..: :.||.|.|    |.|...|    |:
  Rat   196 GG-FDGQARQPTPPFFGRDRSPLRRSPPRASYVAPLTAQPATYRAQPSVSLGAAYRAQP----SA 255

  Fly   170 NQGQGFRNK--------------------FAGG--------------GKFGG---SAGNEGRFGS 197
            :.|.|:|.:                    :.|.              |.:||   ||.....:|.
  Rat   256 SLGVGYRTQPMTAQAASYRAQPSVSLGAPYRGQLASPSSQSAAASSLGPYGGVQPSASALSTYGG 320

  Fly   198 --------NRFQQRDNS----GPQPGRRNFKNSPTSGYRGGGNNSDFQGGSSSSGGGGSVNQRAG 250
                    |.:..:.:|    |.||.....:.:.:.|.|...::.:.||.:||.|..|:.....|
  Rat   321 QAAAASSLNSYGAQGSSLASYGNQPSSYGAQAASSYGVRAAASSYNTQGAASSLGSYGAQAASYG 385

  Fly   251 G---------GGPGPSHVRQDRRGF---ALPVEHQQ-----------------------QQMGF- 279
            .         |....|:..|....:   :.|...||                       |...:
  Rat   386 AQSAASSLAYGAQAASYNAQPSASYSAQSAPYAAQQAASYSSQPAAYVAQPAAAAAYASQPAAYA 450

  Fly   280 --------GRFGNGP-----MNS-------GNRGTNGGNPPGGRGFFNGGGGGFNDRRDSS---- 320
                    |.:|..|     :||       |..|:.|...........|....:..:..::
  Rat   451 AQATTPMAGSYGAQPVVQTQLNSYGAQASMGLSGSYGAQSAAAATGSYGAAAAYGAQPSATLAAP 515

  Fly   321 HETSS-------------PQGGPSKRGGSGGRNHN-----------QNGINAYHSEFPPLGSGGG 361
            :.|.|             ||...|.||..|.....           ..|..|..:..||
  Rat   516 YRTQSSASLAASYAAQQHPQAAASYRGQPGSAYDGTGQPSAAYLSMSQGAVANANSTPP------ 574

  Fly   362 GPGQRNRFNGPR 373
             |.:|.|.:.||
  Rat   575 -PYERTRLSPPR 585

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7903	NP_651755.2	RRM	<4..168	CDD:223796	62/192 (32%)
CG7903	NP_651755.2	RRM_SF	6..70	CDD:302621	32/64 (50%)
Rbm14	NP_596879.1	RRM1_CoAA	1..71	CDD:410020
		PABP-1234	<3..280	CDD:130689	66/218 (30%)
		RRM2_CoAA	79..146	CDD:410021	33/66 (50%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1563362at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920