back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7896 and TRIL

DIOPT Version :10

Sequence 1:	NP_651754.1	Gene:	CG7896 / 43552	FlyBaseID:	FBgn0039728	Length:	1392	Species:	Drosophila melanogaster
Sequence 2:	NP_055632.2	Gene:	TRIL / 9865	HGNCID:	22200	Length:	811	Species:	Homo sapiens

Alignment Length:	433	Identity:	122/433 - (28%)
Similarity:	182/433 - (42%)	Gaps:	107/433 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   185 DLKEFYIDRNSLTSVPTNSLNGPSALRHLSLRQNQIGSLLADSFNAQRQLEIIDLRHNVIRSIDS 249
            |:..:.:..|.:|::.....:....||.|.|:.|||.||...:|....:||.:.|.:|:::::..
Human    60 DVLTYSLGGNFITNITAFDFHRLGQLRRLDLQYNQIRSLHPKTFEKLSRLEELYLGNNLLQALAP 124

  Fly   250 LAFKGLQKIREIKLAGNRISHLNSDVFEKLQSLQKLDLSENFFGQFPTVALAAVPGLKHLNLSSN 314
            .....|:|:|.:...||.||.|:...||.|:||.||.|..|..|..|....|.:..|.:|:|.||
Human   125 GTLAPLRKLRILYANGNEISRLSRGSFEGLESLVKLRLDGNALGALPDAVFAPLGNLLYLHLESN 189

  Fly   315 MLQQLDYTHMQVVRSLESLDISRNTITTITPGTFREMGALKYLDLSLNSLRTIEDDALEGLDSLQ 379
            .::.|                .:|        .|.::|.|::|:||.|.|:
Human   190 RIRFL----------------GKN--------AFAQLGKLRFLNLSANELQ-------------- 216

  Fly   380 TLIIKDNNILLVPGSALGRLPQLTSLQLDYNRVAALSAEILGSLQAGDITTLSLSRNVIRELPPG 444
                                |.|        |.||..|.:      ..:::|.||.|.::.|.|.
Human   217 --------------------PSL--------RHAATFAPL------RSLSSLILSANNLQHLGPR 247

  Fly   445 SFQMFSSLHTLDLSGNSLAVINADTFAGLESTLMALKLSQNRLTGLGGAPWVLPE----LRSLDL 505
            .||....|..|.|.||.|..:..:.|.|||: |..|:|..|||:.|   |..|.|    |.:|||
Human   248 IFQHLPRLGLLSLRGNQLTHLAPEAFWGLEA-LRELRLEGNRLSQL---PTALLEPLHSLEALDL 308

  Fly   506 SGNTLTELPSTIFEELENVQSLNLSGNHLTPLTGALFKPLDRLQVIDLSG------CNIRQI--- 561
            |||.|:.|....|..|..::.|:|..|.|:.|:|.:|.....|..:||.|      |.:|.:
Human   309 SGNELSALHPATFGHLGRLRELSLRNNALSALSGDIFAASPALYRLDLDGNGWTCDCRLRGLKRW 373

  Fly   562 ------SGDLLAGLQDLKH---------IYLNDNQLQELQDGS 589
                  .|.||......:|         .||:|   |:||:||
Human   374 MGDWHSQGRLLTVFVQCRHPPALRGKYLDYLDD---QQLQNGS 413

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.