Protein Alignment CG7896 and Islr

DIOPT Version :10

• Sequence 1: NP_651754.1
• Gene: CG7896 / 43552
• FlyBaseID: FBgn0039728
• Length: 1392
• Species: Drosophila melanogaster
• Sequence 2: NP_001119772.1
• Gene: Islr / 686539
• RGDID: 1596359
• Length: 428
• Species: Rattus norvegicus
• Alignment Length: 426
• Identity: 101/426 - (23%)
• Similarity: 164/426 - (38%)
• Gaps: 102/426 - (23%)

  Fly   207 PSALRHLSLRQNQIGSLLADSFNAQRQLEIIDLRHNVIRSIDSLAFKGLQKIREIKLAGNRISHL 271
            |:.:..|||..|::..||..||.....|:.:.|.||.|||:...|...|             .||
  Rat    49 PANVTTLSLSANRLPVLLEGSFREVPLLQSLWLAHNEIRSVAVGALAPL-------------GHL 100

  Fly   272 NSDVFEKLQSLQKLDLSENFFGQFPTVALAAVPGLKHLNLSSNMLQQLDYTHMQVVRSLESLDIS 336
            .|           ||||.|...:|....|..:..|:.|.:.||.|..:.....:.:.:|.||.::
  Rat   101 KS-----------LDLSHNLISEFAWSDLHNLSALQLLKMDSNELAFIPRDAFRSLHALRSLQLN 154

  Fly   337 RNTITTITPGTFREMGALKYLDLSLNSLRTIEDDALEGLDSLQT-------LIIKDNNIL----- 389
            .|.:..:..|||..:.:|.:|.::.|..     |...|:...:|       .|.:.:||.
  Rat   155 HNRLHALAEGTFAPLTSLSHLQINHNPF-----DCTCGIVWFKTWALATAVSIPEQDNIACTSPH 214

  Fly   390 LVPGSALGRLPQL----TSLQLDYNRVAALSAEILGSLQAGDITTLSLSRNVIRELPPGSFQMFS 450
            ::.|:.|.|||.|    .|:||.|.     .::....|:.|.:  |:|..:|..:..|   |:..
  Rat   215 VLKGTPLSRLPPLPCSAPSVQLSYQ-----PSQDGAELRPGFV--LALHCDVDGQPVP---QLHW 269

  Fly   451 SLHTLDLSGNSLAVINADTFAGLESTLMALKLS-QNRLTGLGGAPWVLPELRSLD------LSGN 508
            .:||   .|.::.:.:.:..........||..| |.|.........::|:...|:      |:.|
  Rat   270 HIHT---PGGTVEIASPNVGTDGRPLPGALAASGQPRFQAFANGSLLIPDFGKLEEGTYSCLATN 331

  Fly   509 TLTELPSTIFEEL-------ENVQSLNLSG------------NHLTPLTGALFKPLDRLQVIDLS 554
            .|....|::...|       |:.......|            |.:.| :|    |.|.:.:|.||
  Rat   332 ELGSAESSVNVALATPGEGGEDAVGRKFHGKTVEGKGCYTVDNEVQP-SG----PEDNVVIIYLS 391

  Fly   555 ------------GCNIRQISGDLLAGLQDLKHIYLN 578
                        |...:|:||.||.| |.|..::|:
  Rat   392 RAGPPEAAVTAEGRPAQQLSGVLLLG-QSLLVLFLS 426

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7896	NP_651754.1	PRK15370	20..>410	CDD:185268	58/218 (27%)
		leucine-rich repeat	109..132	CDD:275380
		leucine-rich repeat	133..161	CDD:275380
		leucine-rich repeat	162..185	CDD:275380
		leucine-rich repeat	186..209	CDD:275380	1/1 (100%)
		leucine-rich repeat	210..233	CDD:275380	8/22 (36%)
		leucine-rich repeat	234..257	CDD:275380	9/22 (41%)
		PLN00113	237..>750	CDD:215061	91/396 (23%)
		leucine-rich repeat	258..281	CDD:275380	3/22 (14%)
		leucine-rich repeat	282..329	CDD:275380	12/46 (26%)
		leucine-rich repeat	330..353	CDD:275380	7/22 (32%)
		leucine-rich repeat	354..377	CDD:275380	5/22 (23%)
		leucine-rich repeat	378..401	CDD:275380	8/34 (24%)
		leucine-rich repeat	402..425	CDD:275380	6/26 (23%)
		leucine-rich repeat	428..451	CDD:275380	5/22 (23%)
		leucine-rich repeat	452..473	CDD:275380	3/20 (15%)
		leucine-rich repeat	477..497	CDD:275378	5/20 (25%)
		leucine-rich repeat	500..523	CDD:275380	6/35 (17%)
		leucine-rich repeat	524..547	CDD:275380	5/34 (15%)
		leucine-rich repeat	548..571	CDD:275380	10/34 (29%)
		leucine-rich repeat	572..595	CDD:275380	2/7 (29%)
		leucine-rich repeat	596..619	CDD:275380
		leucine-rich repeat	620..643	CDD:275380
		leucine-rich repeat	644..667	CDD:275380
		leucine-rich repeat	668..691	CDD:275380
		LRR	<684..1020	CDD:443914
		leucine-rich repeat	692..715	CDD:275380
		leucine-rich repeat	716..739	CDD:275380
		leucine-rich repeat	740..761	CDD:275380
		leucine-rich repeat	764..789	CDD:275380
		leucine-rich repeat	790..810	CDD:275380
		leucine-rich repeat	818..850	CDD:275380
		leucine-rich repeat	863..883	CDD:275378
		leucine-rich repeat	884..907	CDD:275380
		leucine-rich repeat	908..933	CDD:275380
		leucine-rich repeat	934..955	CDD:275380
		leucine-rich repeat	958..982	CDD:275380
		leucine-rich repeat	983..1055	CDD:275380
		leucine-rich repeat	1009..1033	CDD:275380
		leucine-rich repeat	1058..1085	CDD:275380
		LRRCT	1121..1168	CDD:214507
Islr	NP_001119772.1	leucine-rich repeat	32..51	CDD:275380	1/1 (100%)
		LRR	<51..>182	CDD:443914	42/154 (27%)
		leucine-rich repeat	52..75	CDD:275380	8/22 (36%)
		leucine-rich repeat	76..99	CDD:275380	9/35 (26%)
		leucine-rich repeat	100..123	CDD:275380	9/33 (27%)
		leucine-rich repeat	124..147	CDD:275380	5/22 (23%)
		leucine-rich repeat	148..171	CDD:275380	7/22 (32%)
		PCC	153..>227	CDD:188093	18/78 (23%)
		Ig	239..343	CDD:472250	21/116 (18%)
		Ig strand B	253..257	CDD:409353	2/3 (67%)
		Ig strand C	266..270	CDD:409353	1/3 (33%)
		Ig strand E	310..314	CDD:409353	0/3 (0%)
		Ig strand F	324..329	CDD:409353	0/4 (0%)
		Ig strand G	337..340	CDD:409353	1/2 (50%)