DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG7896 and lrrc4.2

DIOPT Version :9

Sequence 1:NP_651754.1 Gene:CG7896 / 43552 FlyBaseID:FBgn0039728 Length:1392 Species:Drosophila melanogaster
Sequence 2:NP_001093494.1 Gene:lrrc4.2 / 566572 ZFINID:ZDB-GENE-030131-7997 Length:644 Species:Danio rerio


Alignment Length:699 Identity:162/699 - (23%)
Similarity:264/699 - (37%) Gaps:189/699 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly   193 RNSLTSVPTNSLNGPSALRHLSLRQNQIGSLLADSFNAQRQLEIIDLRHNVIRSIDSLAFKGLQK 257
            |.||..||...   |:..|||:|.:|.|.::.|.:|...|.||::.|..|.||.|:..||.||..
Zfish    57 RRSLVRVPPGI---PATTRHLNLMENSIETIEAGTFQHLRHLEVLQLGRNSIRQIEVGAFSGLNS 118

  Fly   258 IREIKLAGNRISHLNSDVFEKLQSLQKLDLSENFFGQFPTVALAAVPGLKHLNLSSNMLQQLDY- 321
            :..::|..||::.:.|..||.|..|::|.|..|.....|:.|...||.|..|:|..  |::|:| 
Zfish   119 LNTLELFDNRLTVIPSGAFEYLSKLRELWLRSNPIESIPSYAFNRVPSLMRLDLGE--LRKLEYI 181

  Fly   322 ---------------------THMQVVR---SLESLDISRNTITTITPGTFREMGALKYLDLSLN 362
                                 ..|.|:.   .||.|::|.|....:.||:||.:.:||.|.:..:
Zfish   182 SEGAFEGLHNLKYLNLGMCNLREMPVLTPLVGLEELEMSENYFPELKPGSFRGLKSLKKLWIMNS 246

  Fly   363 SLRTIEDDALEGLDSLQTLIIKDNNILLVPGSALGRLPQLTSLQLDYN--RVAALSAEILGSLQA 425
            .:.|||.:|.:.:.:|..|.:..||:..:|......|..|..|.|.:|  |...           
Zfish   247 RITTIERNAFDDVTALVELNLAHNNLSSLPHDLFAPLSYLVELHLHHNPWRCDC----------- 300

  Fly   426 GDITTLSLSRNVIRELPPGSFQMFSSLHT-LDLSGNSLAVINADTFAGLESTLMALKLSQNRLTG 489
             |:..|:.   .:||..|.:.......|| ..|.|..|..::..||.                  
Zfish   301 -DVVWLAW---WLREYIPTNSTCCGRCHTPAYLRGRYLVEVDQSTFQ------------------ 343

  Fly   490 LGGAPWVLPELRSLDLSGNTLTELPSTIFEELENVQSLNLSGNHLTPLTGALFKPLDRLQVIDLS 554
             ..||::|...|.|::|...:.||.... ..:.:|:.|..:|..||                  .
Zfish   344 -CSAPFILDAPRDLNISAERVAELKCRT-APMSSVRWLLPNGTVLT------------------H 388

  Fly   555 GCNIRQISGDLLAGLQDLKHIYLNDNQLQELQDGSFVNLWNISSID------LSNNRIGSIRSGA 613
            |.|..:||             .|||..|         |..|:...|      :..|..|:..:.|
Zfish   389 GSNHPRIS-------------VLNDGTL---------NFSNVLPADTGVYTCMVTNMAGNSNASA 431

  Fly   614 FVNVMKLQKLDLHGNQLSAFKGEYFNTGTGIEELDISDNQLSYLFPSSFRIHPRLREIRAANNKF 678
            ::||   ...:|:.:.||     ||.|.| :||::.:..::  :.|.:....|            
Zfish   432 YLNV---TAAELNTSNLS-----YFTTVT-VEEVEPTSQEV--IKPKTVTASP------------ 473

  Fly   679 SFFPAELISTLQYLEHIDLSHNQLKTIEELDFARLPRLRVLLVANNQLDMVSEMAFHNSTQLQI- 742
            |.|....|||...|         |:|..::.   :|.:|........||.|.:     :|::.| 
Zfish   474 SVFQPVFISTPTVL---------LQTPRQVS---VPTVRGTTRPPASLDEVMK-----TTKIIIG 521

  Fly   743 LDLAHNNLDRIGERTFEGLVRLEQLNLEGNRLSELSDGVFERTKLQMLENINLAHNRFEYAPLNA 807
            ..:|...|..:....|..|.:..|     .|.:..:.|..|  .:||.||::..|..        
Zfish   522 CFVAVTLLAAVMLIAFYKLRKRHQ-----QRSTVAASGTME--AIQMDENVSTTHAG-------- 571

  Fly   808 LQRQFFFVSSVDLSHNKIKELPGDDSIMV-NIKRIDLSFNPLSSKAVHN 855
                              ..:||:..:|: :::..:.::.|.|.:..|:
Zfish   572 ------------------TSIPGECGMMLPSLRDHNSTYKPSSYRPAHS 602

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG7896NP_651754.1 LRR_8 109..172 CDD:290566
leucine-rich repeat 109..132 CDD:275380
LRR_RI <132..338 CDD:238064 53/169 (31%)
leucine-rich repeat 133..161 CDD:275380
LRR_8 160..220 CDD:290566 11/26 (42%)
leucine-rich repeat 162..185 CDD:275380
leucine-rich repeat 186..209 CDD:275380 6/15 (40%)
leucine-rich repeat 210..233 CDD:275380 8/22 (36%)
LRR_8 232..290 CDD:290566 22/57 (39%)
leucine-rich repeat 234..257 CDD:275380 11/22 (50%)
leucine-rich repeat 258..281 CDD:275380 7/22 (32%)
LRR_RI 273..535 CDD:238064 70/289 (24%)
LRR_8 281..338 CDD:290566 20/81 (25%)
leucine-rich repeat 282..329 CDD:275380 16/71 (23%)
LRR_8 328..388 CDD:290566 19/62 (31%)
leucine-rich repeat 330..353 CDD:275380 9/22 (41%)
leucine-rich repeat 354..377 CDD:275380 7/22 (32%)
leucine-rich repeat 378..401 CDD:275380 6/22 (27%)
leucine-rich repeat 402..425 CDD:275380 5/24 (21%)
leucine-rich repeat 428..451 CDD:275380 4/22 (18%)
LRR_8 429..487 CDD:290566 11/58 (19%)
leucine-rich repeat 452..473 CDD:275380 7/21 (33%)
leucine-rich repeat 477..497 CDD:275378 2/19 (11%)
LRR_8 498..558 CDD:290566 11/59 (19%)
leucine-rich repeat 500..523 CDD:275380 5/22 (23%)
LRR_RI 502..769 CDD:238064 56/273 (21%)
leucine-rich repeat 524..547 CDD:275380 5/22 (23%)
leucine-rich repeat 548..571 CDD:275380 4/22 (18%)
LRR_8 572..630 CDD:290566 13/63 (21%)
leucine-rich repeat 572..595 CDD:275380 5/22 (23%)
leucine-rich repeat 596..619 CDD:275380 6/28 (21%)
LRR_8 619..678 CDD:290566 11/58 (19%)
leucine-rich repeat 620..643 CDD:275380 6/22 (27%)
leucine-rich repeat 644..667 CDD:275380 3/22 (14%)
LRR_8 666..726 CDD:290566 11/59 (19%)
leucine-rich repeat 668..691 CDD:275380 5/22 (23%)
leucine-rich repeat 692..715 CDD:275380 3/22 (14%)
LRR_8 714..774 CDD:290566 12/60 (20%)
leucine-rich repeat 716..739 CDD:275380 4/22 (18%)
leucine-rich repeat 740..761 CDD:275380 4/21 (19%)
leucine-rich repeat 764..789 CDD:275380 4/24 (17%)
leucine-rich repeat 790..810 CDD:275380 3/19 (16%)
leucine-rich repeat 818..850 CDD:275380 4/32 (13%)
leucine-rich repeat 863..883 CDD:275378
LRR_RI <878..1070 CDD:238064
LRR_8 884..944 CDD:290566
LRR_4 884..925 CDD:289563
leucine-rich repeat 884..907 CDD:275380
leucine-rich repeat 908..933 CDD:275380
leucine-rich repeat 934..955 CDD:275380
leucine-rich repeat 958..982 CDD:275380
leucine-rich repeat 983..1055 CDD:275380
leucine-rich repeat 1009..1033 CDD:275380
leucine-rich repeat 1058..1085 CDD:275380
TPKR_C2 1121..1168 CDD:301599
lrrc4.2NP_001093494.1 leucine-rich repeat 71..94 CDD:275380 8/22 (36%)
LRR_8 72..129 CDD:290566 22/56 (39%)
LRR_RI 74..>276 CDD:238064 61/203 (30%)
leucine-rich repeat 95..118 CDD:275380 11/22 (50%)
leucine-rich repeat 119..142 CDD:275380 7/22 (32%)
LRR_8 141..202 CDD:290566 14/62 (23%)
leucine-rich repeat 143..166 CDD:275380 7/22 (32%)
leucine-rich repeat 167..191 CDD:275380 6/25 (24%)
leucine-rich repeat 192..213 CDD:275380 2/20 (10%)
LRR_8 213..272 CDD:290566 19/58 (33%)
leucine-rich repeat 214..237 CDD:275380 9/22 (41%)
leucine-rich repeat 238..261 CDD:275380 7/22 (32%)
leucine-rich repeat 262..283 CDD:275380 5/20 (25%)
LRRCT 294..345 CDD:214507 14/84 (17%)
IG_like 353..435 CDD:214653 24/122 (20%)
Ig 365..435 CDD:299845 21/110 (19%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.910

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