DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7896 and Lapsyn

DIOPT Version :9

Sequence 1:	NP_651754.1	Gene:	CG7896 / 43552	FlyBaseID:	FBgn0039728	Length:	1392	Species:	Drosophila melanogaster
Sequence 2:	NP_611561.1	Gene:	Lapsyn / 37418	FlyBaseID:	FBgn0034602	Length:	343	Species:	Drosophila melanogaster

Alignment Length:	283	Identity:	72/283 - (25%)
Similarity:	109/283 - (38%)	Gaps:	88/283 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   428 ITTLSLSRNVIRELPPGSFQMFSSLHTLDLSGNSLAVINADTFAGLESTLMALKLSQNRLTGLGG 492
            :..|.||.|.||:|...|||.::.:..|.|..|.:..:...||..|.|
  Fly    60 VEVLDLSHNRIRKLKTSSFQRYTDIKFLMLYDNMILSVEVGTFEPLTS----------------- 107

  Fly   493 APWVLPELRSLDLSGNTLTELPSTIFEELENVQSLNLSGNHLTPLT-GALFKPLDR-LQVIDLSG 555
                   |:.:|||.|.||.:|..:| :|..:::|.:..|.||.|. .||.||:.. |:.::::|
  Fly   108 -------LQEIDLSNNGLTTIPLELF-QLPRLRNLYIDSNELTSLNLQALEKPIRAPLEYLNVAG 164

  Fly   556 CNIRQISGDLLAGLQDLKHIYLNDNQLQELQD-GSFVNLWNISSIDLSNNRIGSIRSGAFVNVMK 619
            |                        :||||.| |....||.:::   |.|.:.:.|..:..|:..
  Fly   165 C------------------------ELQELPDLGILPKLWQLNA---SMNPLQNFRIDSLANMCH 202

  Fly   620 LQKLDLHGNQLS-----AFKGEYFNTGTG-------IEELDISDNQLSYLFPSSFRIHPRLREIR 672
            ||.:||..:|||     .........|..       :|.|||.:..|.|
  Fly   203 LQVIDLTKSQLSQCGCQQVTNHLMMLGASPKFVPVCLEALDIRECPLPY---------------- 251

  Fly   673 AANNKFSFFP--AELISTLQYLE 693
               |:....|  |...:|||:.|
  Fly   252 ---NRTIHSPTFASCQTTLQFAE 271

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7896	NP_651754.1	LRR_8	109..172	CDD:290566
		leucine-rich repeat	109..132	CDD:275380
		LRR_RI	<132..338	CDD:238064
		leucine-rich repeat	133..161	CDD:275380
		LRR_8	160..220	CDD:290566
		leucine-rich repeat	162..185	CDD:275380
		leucine-rich repeat	186..209	CDD:275380
		leucine-rich repeat	210..233	CDD:275380
		LRR_8	232..290	CDD:290566
		leucine-rich repeat	234..257	CDD:275380
		leucine-rich repeat	258..281	CDD:275380
		LRR_RI	273..535	CDD:238064	29/106 (27%)
		LRR_8	281..338	CDD:290566
		leucine-rich repeat	282..329	CDD:275380
		LRR_8	328..388	CDD:290566
		leucine-rich repeat	330..353	CDD:275380
		leucine-rich repeat	354..377	CDD:275380
		leucine-rich repeat	378..401	CDD:275380
		leucine-rich repeat	402..425	CDD:275380
		leucine-rich repeat	428..451	CDD:275380	10/22 (45%)
		LRR_8	429..487	CDD:290566	17/57 (30%)
		leucine-rich repeat	452..473	CDD:275380	5/20 (25%)
		leucine-rich repeat	477..497	CDD:275378	0/19 (0%)
		LRR_8	498..558	CDD:290566	22/61 (36%)
		leucine-rich repeat	500..523	CDD:275380	10/22 (45%)
		LRR_RI	502..769	CDD:238064	54/209 (26%)
		leucine-rich repeat	524..547	CDD:275380	9/23 (39%)
		leucine-rich repeat	548..571	CDD:275380	3/22 (14%)
		LRR_8	572..630	CDD:290566	16/58 (28%)
		leucine-rich repeat	572..595	CDD:275380	7/23 (30%)
		leucine-rich repeat	596..619	CDD:275380	4/22 (18%)
		LRR_8	619..678	CDD:290566	15/70 (21%)
		leucine-rich repeat	620..643	CDD:275380	8/27 (30%)
		leucine-rich repeat	644..667	CDD:275380	6/22 (27%)
		LRR_8	666..726	CDD:290566	7/30 (23%)
		leucine-rich repeat	668..691	CDD:275380	5/24 (21%)
		leucine-rich repeat	692..715	CDD:275380	1/2 (50%)
		LRR_8	714..774	CDD:290566
		leucine-rich repeat	716..739	CDD:275380
		leucine-rich repeat	740..761	CDD:275380
		leucine-rich repeat	764..789	CDD:275380
		leucine-rich repeat	790..810	CDD:275380
		leucine-rich repeat	818..850	CDD:275380
		leucine-rich repeat	863..883	CDD:275378
		LRR_RI	<878..1070	CDD:238064
		LRR_8	884..944	CDD:290566
		LRR_4	884..925	CDD:289563
		leucine-rich repeat	884..907	CDD:275380
		leucine-rich repeat	908..933	CDD:275380
		leucine-rich repeat	934..955	CDD:275380
		leucine-rich repeat	958..982	CDD:275380
		leucine-rich repeat	983..1055	CDD:275380
		leucine-rich repeat	1009..1033	CDD:275380
		leucine-rich repeat	1058..1085	CDD:275380
		TPKR_C2	1121..1168	CDD:301599
Lapsyn	NP_611561.1	leucine-rich repeat	39..59	CDD:275380
		LRR_8	58..118	CDD:290566	22/81 (27%)
		leucine-rich repeat	60..83	CDD:275380	10/22 (45%)
		leucine-rich repeat	84..107	CDD:275380	6/22 (27%)
		LRR_RI	<94..>249	CDD:238064	50/206 (24%)
		LRR_8	106..167	CDD:290566	23/109 (21%)
		LRR_4	106..145	CDD:289563	15/63 (24%)
		leucine-rich repeat	108..130	CDD:275380	10/22 (45%)
		leucine-rich repeat	131..154	CDD:275380	9/22 (41%)
		leucine-rich repeat	157..178	CDD:275380	9/44 (20%)
		leucine-rich repeat	179..202	CDD:275380	6/25 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24366
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100