DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7896 and swi2

DIOPT Version :9

Sequence 1:	NP_651754.1	Gene:	CG7896 / 43552	FlyBaseID:	FBgn0039728	Length:	1392	Species:	Drosophila melanogaster
Sequence 2:	NP_611247.3	Gene:	swi2 / 37010	FlyBaseID:	FBgn0034262	Length:	499	Species:	Drosophila melanogaster

Alignment Length:	311	Identity:	69/311 - (22%)
Similarity:	121/311 - (38%)	Gaps:	63/311 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   497 LPELRSLDLSGNTLTELPSTIFEELENVQSLNLSGNHLTPLTGALFKPLDRLQVIDLSGCNIRQI 561
            ||.||||.:..:..||.... |.|:..:.::|:|..:|:.::...||.:..|:|:||....:.|:
  Fly   129 LPRLRSLTIEYSGFTEFKFD-FPEMLELHTINISWTNLSYISSRTFKRVHPLKVLDLRWNQLIQL 192

  Fly   562 SGDLLAGLQDLKHIYLNDNQLQELQDGSFVNLWNISSIDLSNNRIGSIRSGAFVNVMKLQKLDLH 626
            .|.||.. ::.:.:||..|.            ||.:                  ...|...|...
  Fly   193 DGPLLLP-RNFEQLYLAGNP------------WNCT------------------RNFKWLLLQPE 226

  Fly   627 GNQLSAFKGEYFNTGTGIEELDISDNQLSYLFPSSFRIHPRLREIRAANNKFSFFPAELISTLQY 691
            ..:|...:.|...|....:|     .|:..:      :|.:|...|...:.     .:|.:....
  Fly   227 KGRLVVDRDELICTDRKYKE-----RQMLMV------MHYKLELKRQCQSH-----EDLRNCTCL 275

  Fly   692 LEHI-DLSHNQLKTI--EELDFARLP-----RLRVLLVANNQLDMVSEMA----FHNSTQLQILD 744
            :.|| ..:|..|.|:  ..|.|.|||     ....|::.:|.:..::.:.    :.:...:|:.:
  Fly   276 MHHILPKTHIPLYTVNCSHLQFHRLPDFLPDNTTTLVINDNMISDINPLRDNPHYRHVVDMQLEN 340

  Fly   745 LAHNNLDRIGERTFEGLVRLEQLNLEGNRLSELSDGVFERTKLQMLENINL 795
            ...:|:|.: |.|: .|.....|||.||.|.:|.....:.. |...||.||
  Fly   341 NQISNVDNL-EDTY-WLQNFRLLNLRGNNLRKLHVYALDNA-LDDNENANL 388

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7896	NP_651754.1	LRR_8	109..172	CDD:290566
		leucine-rich repeat	109..132	CDD:275380
		LRR_RI	<132..338	CDD:238064
		leucine-rich repeat	133..161	CDD:275380
		LRR_8	160..220	CDD:290566
		leucine-rich repeat	162..185	CDD:275380
		leucine-rich repeat	186..209	CDD:275380
		leucine-rich repeat	210..233	CDD:275380
		LRR_8	232..290	CDD:290566
		leucine-rich repeat	234..257	CDD:275380
		leucine-rich repeat	258..281	CDD:275380
		LRR_RI	273..535	CDD:238064	12/37 (32%)
		LRR_8	281..338	CDD:290566
		leucine-rich repeat	282..329	CDD:275380
		LRR_8	328..388	CDD:290566
		leucine-rich repeat	330..353	CDD:275380
		leucine-rich repeat	354..377	CDD:275380
		leucine-rich repeat	378..401	CDD:275380
		leucine-rich repeat	402..425	CDD:275380
		leucine-rich repeat	428..451	CDD:275380
		LRR_8	429..487	CDD:290566
		leucine-rich repeat	452..473	CDD:275380
		leucine-rich repeat	477..497	CDD:275378	69/311 (22%)
		LRR_8	498..558	CDD:290566	18/59 (31%)
		leucine-rich repeat	500..523	CDD:275380	8/22 (36%)
		LRR_RI	502..769	CDD:238064	54/278 (19%)
		leucine-rich repeat	524..547	CDD:275380	5/22 (23%)
		leucine-rich repeat	548..571	CDD:275380	8/22 (36%)
		LRR_8	572..630	CDD:290566	7/57 (12%)
		leucine-rich repeat	572..595	CDD:275380	3/22 (14%)
		leucine-rich repeat	596..619	CDD:275380	0/22 (0%)
		LRR_8	619..678	CDD:290566	10/58 (17%)
		leucine-rich repeat	620..643	CDD:275380	4/22 (18%)
		leucine-rich repeat	644..667	CDD:275380	3/22 (14%)
		LRR_8	666..726	CDD:290566	15/67 (22%)
		leucine-rich repeat	668..691	CDD:275380	3/22 (14%)
		leucine-rich repeat	692..715	CDD:275380	10/30 (33%)
		LRR_8	714..774	CDD:290566	14/68 (21%)
		leucine-rich repeat	716..739	CDD:275380	2/26 (8%)
		leucine-rich repeat	740..761	CDD:275380	5/20 (25%)
		leucine-rich repeat	764..789	CDD:275380	8/24 (33%)
		leucine-rich repeat	790..810	CDD:275380	4/6 (67%)
		leucine-rich repeat	818..850	CDD:275380
		leucine-rich repeat	863..883	CDD:275378
		LRR_RI	<878..1070	CDD:238064
		LRR_8	884..944	CDD:290566
		LRR_4	884..925	CDD:289563
		leucine-rich repeat	884..907	CDD:275380
		leucine-rich repeat	908..933	CDD:275380
		leucine-rich repeat	934..955	CDD:275380
		leucine-rich repeat	958..982	CDD:275380
		leucine-rich repeat	983..1055	CDD:275380
		leucine-rich repeat	1009..1033	CDD:275380
		leucine-rich repeat	1058..1085	CDD:275380
		TPKR_C2	1121..1168	CDD:301599
swi2	NP_611247.3	LRR	<117..384	CDD:227223	65/305 (21%)
		leucine-rich repeat	132..154	CDD:275378	8/22 (36%)
		leucine-rich repeat	155..178	CDD:275378	5/22 (23%)
		leucine-rich repeat	179..201	CDD:275378	8/22 (36%)
		leucine-rich repeat	202..214	CDD:275378	4/23 (17%)
		leucine-rich repeat	287..307	CDD:275378	7/19 (37%)
		leucine-rich repeat	308..332	CDD:275378	2/23 (9%)
		leucine-rich repeat	333..357	CDD:275378	6/25 (24%)
		leucine-rich repeat	358..385	CDD:275378	8/27 (30%)
		leucine-rich repeat	386..398	CDD:275378	2/3 (67%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24366
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100