Protein Alignment CG7896 and LRRC66

DIOPT Version :10

• Sequence 1: NP_651754.1
• Gene: CG7896 / 43552
• FlyBaseID: FBgn0039728
• Length: 1392
• Species: Drosophila melanogaster
• Sequence 2: XP_047271600.1
• Gene: LRRC66 / 339977
• HGNCID: 34299
• Length: 932
• Species: Homo sapiens
• Alignment Length: 288
• Identity: 76/288 - (26%)
• Similarity: 115/288 - (39%)
• Gaps: 44/288 - (15%)

  Fly   428 ITTLSLSRNVIRELPPGSFQMFSSLHTLDLSGNSLAVINAD--------------TFAGLESTLM 478
            |..|.||.|:|.::....|....:|..|:||.|::..::.|              :|......|.
Human   139 IKHLDLSNNLISKITLSPFAYLHALEVLNLSNNAIHSLSLDLLSPKSSWVKRHRSSFRNRFPLLK 203

  Fly   479 ALKLSQNRLTGLGGAPWVLPELRSLDLSGNTLTELPSTIFEELENVQSLNLSGNHLTPLTGALFK 543
            .|.|.:|:|:......|.|..|:|||||.|.:.::..:.|.....:::|.|..|.:..:....||
Human   204 VLILQRNKLSDTPKGLWKLKSLQSLDLSFNGILQIGWSDFHNCLQLENLCLKSNKIFKIPPQAFK 268

  Fly   544 PLDRLQVIDLSGCNIRQISGDLLAGLQDLKHIY--LNDNQ---------LQELQDGSFVNLWNIS 597
            .|.:|||||||...:..|...::..| :..|:.  |.||.         .|.....|:...||:
Human   269 DLKKLQVIDLSNNALITILPMMIIAL-EFPHLVVDLADNNWQCDDSVAVFQNFISESWRKKWNV- 331

  Fly   598 SIDLSNNRIGSIRSGA------FVNVMKLQKLDLHG-NQLSAFKGEYFNTG--TGIEELDISDNQ 653
               :.|..|||..:..      .....:|..:.||. ..|...|.|....|  |||..|......
Human   332 ---ICNRSIGSEEANGGTPQSRISRETRLPPIHLHRMKSLIRSKAERPQGGRHTGISTLGKKAKA 393

  Fly   654 LSYLFPSSFRIHPR----LREIRAANNK 677
            .|.|.....|: ||    .|:::||..|
Human   394 GSGLRKKQRRL-PRSVRSTRDVQAAGKK 420

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7896	NP_651754.1	PRK15370	20..>410	CDD:185268
		leucine-rich repeat	109..132	CDD:275380
		leucine-rich repeat	133..161	CDD:275380
		leucine-rich repeat	162..185	CDD:275380
		leucine-rich repeat	186..209	CDD:275380
		leucine-rich repeat	210..233	CDD:275380
		leucine-rich repeat	234..257	CDD:275380
		PLN00113	237..>750	CDD:215061	76/288 (26%)
		leucine-rich repeat	258..281	CDD:275380
		leucine-rich repeat	282..329	CDD:275380
		leucine-rich repeat	330..353	CDD:275380
		leucine-rich repeat	354..377	CDD:275380
		leucine-rich repeat	378..401	CDD:275380
		leucine-rich repeat	402..425	CDD:275380
		leucine-rich repeat	428..451	CDD:275380	7/22 (32%)
		leucine-rich repeat	452..473	CDD:275380	7/34 (21%)
		leucine-rich repeat	477..497	CDD:275378	6/19 (32%)
		leucine-rich repeat	500..523	CDD:275380	8/22 (36%)
		leucine-rich repeat	524..547	CDD:275380	6/22 (27%)
		leucine-rich repeat	548..571	CDD:275380	9/22 (41%)
		leucine-rich repeat	572..595	CDD:275380	6/33 (18%)
		leucine-rich repeat	596..619	CDD:275380	4/28 (14%)
		leucine-rich repeat	620..643	CDD:275380	7/25 (28%)
		leucine-rich repeat	644..667	CDD:275380	5/22 (23%)
		leucine-rich repeat	668..691	CDD:275380	4/10 (40%)
		LRR	<684..1020	CDD:443914
		leucine-rich repeat	692..715	CDD:275380
		leucine-rich repeat	716..739	CDD:275380
		leucine-rich repeat	740..761	CDD:275380
		leucine-rich repeat	764..789	CDD:275380
		leucine-rich repeat	790..810	CDD:275380
		leucine-rich repeat	818..850	CDD:275380
		leucine-rich repeat	863..883	CDD:275378
		leucine-rich repeat	884..907	CDD:275380
		leucine-rich repeat	908..933	CDD:275380
		leucine-rich repeat	934..955	CDD:275380
		leucine-rich repeat	958..982	CDD:275380
		leucine-rich repeat	983..1055	CDD:275380
		leucine-rich repeat	1009..1033	CDD:275380
		leucine-rich repeat	1058..1085	CDD:275380
		LRRCT	1121..1168	CDD:214507
LRRC66	XP_047271600.1	leucine-rich repeat	116..138	CDD:275380
		LRR	<138..>307	CDD:443914	47/168 (28%)
		leucine-rich repeat	140..162	CDD:275380	6/21 (29%)
		leucine-rich repeat	163..201	CDD:275380	7/37 (19%)
		leucine-rich repeat	202..224	CDD:275380	7/21 (33%)
		leucine-rich repeat	225..248	CDD:275380	8/22 (36%)
		leucine-rich repeat	249..272	CDD:275380	6/22 (27%)
		leucine-rich repeat	273..294	CDD:275380	8/20 (40%)