DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7896 and haf

DIOPT Version :9

Sequence 1:	NP_651754.1	Gene:	CG7896 / 43552	FlyBaseID:	FBgn0039728	Length:	1392	Species:	Drosophila melanogaster
Sequence 2:	NP_001356954.1	Gene:	haf / 33339	FlyBaseID:	FBgn0261509	Length:	1347	Species:	Drosophila melanogaster

Alignment Length:	377	Identity:	112/377 - (29%)
Similarity:	158/377 - (41%)	Gaps:	74/377 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   211 RHLSLRQNQIG-SLLADSFNAQRQLEIIDLRHNVIRSIDSLAFKGLQKIREIKLAGNRISHLNSD 274
            |.||::.:|:. |.|..:.|...:|:.:||                     :.:..:.||.|...
  Fly    56 RELSVQCDQVDFSQLLAAMNTHARLKPVDL---------------------LYVNNSTISELPDA 99

  Fly   275 VFEKLQSLQKLDLSENFFGQFPTVALAAVPG----LKHLNLSSNMLQQLDYTHMQVVRSLESLDI 335
            ||..| ||..|.||.   .....:|..|..|    |::|||..|:|..:         .:|:|.:
  Fly   100 VFSNL-SLHNLQLSS---CGIQRIATGAFKGQESVLRNLNLQDNLLADV---------PVEALKV 151

  Fly   336 SRNTITTITPGTFREMGALKYLDLSLNSLRTIEDDALEGLDSLQTLIIKDNNILLVPGSALGRLP 400
                           :|.|..||||.|.|..|.|||..||..|.||.:.|||:.|...:..|...
  Fly   152 ---------------LGKLNLLDLSKNQLSHIPDDAFVGLTKLSTLKLNDNNVTLASNAFRGLEQ 201

  Fly   401 QLTSLQLDYNRVAALSAEILGSLQAGDITTLSLSRNVIRELP-PGSFQMF---SSLHTLDLSGNS 461
            .|.:|.|...:...:...|.|   ...:..|.||:|.|:||| .|..::|   .:|..|:|..|.
  Fly   202 SLKNLNLKGTKQRKVPESIRG---LKSLAFLDLSQNGIKELPGAGGIRVFDGLDALTALNLERNL 263

  Fly   462 LAVINADTFAGLESTLMALKLSQNRLTGLG-GAPWVLPELRSLDLSGNTLTELPSTIFEELENVQ 525
            :..|....|||:..||.:|.|..|.|.... ||...|.|||.||:..|.||.||...|.....:.
  Fly   264 IQSIGETAFAGVRKTLSSLSLLNNLLAEFPIGAVHSLKELRVLDIGFNLLTSLPEAAFRGNPGIT 328

  Fly   526 SLNLSGNHLTPLTGALFKPLD-RLQVIDLSG------CNIRQI-----SGDL 565
            .|.|.||.|:.:....|..|: .|:.:.|.|      |.:|.:     :|||
  Fly   329 LLALDGNPLSSVPEGAFAHLNATLRGLSLGGRFLHCDCKLRWVAEWIRNGDL 380

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7896	NP_651754.1	LRR_8	109..172	CDD:290566
		leucine-rich repeat	109..132	CDD:275380
		LRR_RI	<132..338	CDD:238064	32/131 (24%)
		leucine-rich repeat	133..161	CDD:275380
		LRR_8	160..220	CDD:290566	3/8 (38%)
		leucine-rich repeat	162..185	CDD:275380
		leucine-rich repeat	186..209	CDD:275380
		leucine-rich repeat	210..233	CDD:275380	7/22 (32%)
		LRR_8	232..290	CDD:290566	14/57 (25%)
		leucine-rich repeat	234..257	CDD:275380	3/22 (14%)
		leucine-rich repeat	258..281	CDD:275380	6/22 (27%)
		LRR_RI	273..535	CDD:238064	88/270 (33%)
		LRR_8	281..338	CDD:290566	16/60 (27%)
		leucine-rich repeat	282..329	CDD:275380	13/50 (26%)
		LRR_8	328..388	CDD:290566	21/59 (36%)
		leucine-rich repeat	330..353	CDD:275380	2/22 (9%)
		leucine-rich repeat	354..377	CDD:275380	13/22 (59%)
		leucine-rich repeat	378..401	CDD:275380	8/22 (36%)
		leucine-rich repeat	402..425	CDD:275380	5/22 (23%)
		leucine-rich repeat	428..451	CDD:275380	10/26 (38%)
		LRR_8	429..487	CDD:290566	23/61 (38%)
		leucine-rich repeat	452..473	CDD:275380	7/20 (35%)
		leucine-rich repeat	477..497	CDD:275378	7/20 (35%)
		LRR_8	498..558	CDD:290566	22/66 (33%)
		leucine-rich repeat	500..523	CDD:275380	10/22 (45%)
		LRR_RI	502..769	CDD:238064	23/76 (30%)
		leucine-rich repeat	524..547	CDD:275380	7/23 (30%)
		leucine-rich repeat	548..571	CDD:275380	8/29 (28%)
		LRR_8	572..630	CDD:290566
		leucine-rich repeat	572..595	CDD:275380
		leucine-rich repeat	596..619	CDD:275380
		LRR_8	619..678	CDD:290566
		leucine-rich repeat	620..643	CDD:275380
		leucine-rich repeat	644..667	CDD:275380
		LRR_8	666..726	CDD:290566
		leucine-rich repeat	668..691	CDD:275380
		leucine-rich repeat	692..715	CDD:275380
		LRR_8	714..774	CDD:290566
		leucine-rich repeat	716..739	CDD:275380
		leucine-rich repeat	740..761	CDD:275380
		leucine-rich repeat	764..789	CDD:275380
		leucine-rich repeat	790..810	CDD:275380
		leucine-rich repeat	818..850	CDD:275380
		leucine-rich repeat	863..883	CDD:275378
		LRR_RI	<878..1070	CDD:238064
		LRR_8	884..944	CDD:290566
		LRR_4	884..925	CDD:289563
		leucine-rich repeat	884..907	CDD:275380
		leucine-rich repeat	908..933	CDD:275380
		leucine-rich repeat	934..955	CDD:275380
		leucine-rich repeat	958..982	CDD:275380
		leucine-rich repeat	983..1055	CDD:275380
		leucine-rich repeat	1009..1033	CDD:275380
		leucine-rich repeat	1058..1085	CDD:275380
		TPKR_C2	1121..1168	CDD:301599
haf	NP_001356954.1	LRR	<52..>252	CDD:227223	69/247 (28%)
		leucine-rich repeat	86..105	CDD:275380	6/19 (32%)
		leucine-rich repeat	106..129	CDD:275380	7/25 (28%)
		LRR_8	131..189	CDD:338972	27/81 (33%)
		leucine-rich repeat	131..154	CDD:275380	8/46 (17%)
		leucine-rich repeat	155..178	CDD:275380	13/22 (59%)
		leucine-rich repeat	179..202	CDD:275380	8/22 (36%)
		leucine-rich repeat	203..225	CDD:275380	5/24 (21%)
		leucine-rich repeat	226..253	CDD:275380	10/26 (38%)
		LRR_8	254..337	CDD:338972	32/82 (39%)
		leucine-rich repeat	254..302	CDD:275380	17/47 (36%)
		leucine-rich repeat	303..326	CDD:275380	10/22 (45%)
		leucine-rich repeat	327..350	CDD:275380	7/22 (32%)
		PCC	332..>413	CDD:188093	14/49 (29%)
		PRK10927	<1061..>1097	CDD:236797
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24366
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010