DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG7896 and Lrrn4

DIOPT Version :9

Sequence 1:NP_651754.1 Gene:CG7896 / 43552 FlyBaseID:FBgn0039728 Length:1392 Species:Drosophila melanogaster
Sequence 2:NP_796277.2 Gene:Lrrn4 / 320974 MGIID:2445154 Length:733 Species:Mus musculus


Alignment Length:621 Identity:143/621 - (23%)
Similarity:216/621 - (34%) Gaps:214/621 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly   671 IRAANNKFSFFPAELISTLQYLEHIDLSHNQLKTIEELDFARLPRLRVLLVANNQLDMVSEMAFH 735
            :..||......|:.|..||:.|   |.|||.|:.:.|....|||.||||.:.:|::.::      
Mouse    66 LNLANRSLESLPSCLPRTLRSL---DGSHNLLRALSEPVLGRLPELRVLTLHHNRISVL------ 121

  Fly   736 NSTQLQILDLAHNNLDRIGERTFEGLVRLEQLNLEGNRLSELSDGVFERTKLQMLENINLAHNRF 800
                       |...|.:.|                  |.||                       
Mouse   122 -----------HWGRDTLAE------------------LREL----------------------- 134

  Fly   801 EYAPLNALQRQFFFVSSVDLSHNKIKELPGDDSIMVNIKRIDLSFNPLSSKAVHNVLNEPKTVRE 865
                              |||||.:.|||                 |.:..:       ..::|.
Mouse   135 ------------------DLSHNLLTELP-----------------PCAGPS-------GSSLRS 157

  Fly   866 LSLAGTGIENLELLET----PFLQFLNLSHNKLKNVKPEVFQRV-----TLLETLDLSSNQLESL 921
            |:|||..:..| |..|    |.|:.||||.::|.::..|.|..|     ..||.||||...||.:
Mouse   158 LALAGNPLRAL-LPRTFACFPALRLLNLSCSELGHIAQEAFAGVDGGPLAALELLDLSGTSLERV 221

  Fly   922 EDLSMAWPQLQVLQSLDVSNNSFEIVSQSNFGKLEMLRSLRLSHLPQCTRIEKNAFKQLPNLVSL 986
            |.   .|          :.|             |..|:||.|..:|:...:|.:.||..|||..|
Mouse   222 ES---GW----------IRN-------------LPKLKSLFLRKMPRLKTLEGDIFKMTPNLRQL 260

  Fly   987 EAYDLPLLGYLDLQGILELLPGLEVLDIE-VKDSSIGSEQIQPLKHPRLKSLGIRGDRLKSISSG 1050
            :..|.|.|..:..: |.:..|.|:||..: ...||.|     |....::.|:.:.|:.|  |.|.
Mouse   261 DCGDSPALTSVHTE-IFQDTPNLQVLQFQNCNLSSFG-----PWNSSQVLSVSLFGNPL--ICSC 317

  Fly  1051 TLAGLKSNDLSVQLRNTSLNALPPAL----LFPVPRS-SHLSLNVEGSKITVLVPQFLNALEDRR 1110
            .||.|..:.....|...:.....|||    .|..|.| ||||......:.|.|:|......:...
Mouse   318 ELAWLLVDVNKTVLHRAADTMCEPALGSTGPFSGPLSLSHLSNVCRSDQSTTLLPSNPGRFDHSV 382

  Fly  1111 ASLQLQG--------LASNPIVCDCNARALRRWLPSSGMPDVTCASP--------------AYLL 1153
            .:.::||        |::.|.....|.         :.:|.:|..||              |...
Mouse   383 FAPRIQGPSIEQSTALSAQPGGSQQNI---------TKVPSLTMTSPTQGSWMYKDASEETAQST 438

  Fly  1154 NRKLIEVGDDELTCDARRMTSSTSRPTASVPHLLKTSSQLVTRSSSTTEEPLIIWSLEP----TQ 1214
            |.:|:             .:.|.:.|.|:.....:|::.::..:.|:...||:...|||    ..
Mouse   439 NSELV-------------YSPSRALPGAASSGAEQTATHILEPNISSASTPLVSKYLEPLPTSPN 490

  Fly  1215 PPSLKKMK-----------TKAPLMKAQSPIISNDD 1239
            |.||.:.|           |..|  :.:.|::..||
Mouse   491 PRSLPQTKQRTQATPRALHTDPP--QDEIPVLLLDD 524

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG7896NP_651754.1 LRR_8 109..172 CDD:290566
leucine-rich repeat 109..132 CDD:275380
LRR_RI <132..338 CDD:238064
leucine-rich repeat 133..161 CDD:275380
LRR_8 160..220 CDD:290566
leucine-rich repeat 162..185 CDD:275380
leucine-rich repeat 186..209 CDD:275380
leucine-rich repeat 210..233 CDD:275380
LRR_8 232..290 CDD:290566
leucine-rich repeat 234..257 CDD:275380
leucine-rich repeat 258..281 CDD:275380
LRR_RI 273..535 CDD:238064
LRR_8 281..338 CDD:290566
leucine-rich repeat 282..329 CDD:275380
LRR_8 328..388 CDD:290566
leucine-rich repeat 330..353 CDD:275380
leucine-rich repeat 354..377 CDD:275380
leucine-rich repeat 378..401 CDD:275380
leucine-rich repeat 402..425 CDD:275380
leucine-rich repeat 428..451 CDD:275380
LRR_8 429..487 CDD:290566
leucine-rich repeat 452..473 CDD:275380
leucine-rich repeat 477..497 CDD:275378
LRR_8 498..558 CDD:290566
leucine-rich repeat 500..523 CDD:275380
LRR_RI 502..769 CDD:238064 24/97 (25%)
leucine-rich repeat 524..547 CDD:275380
leucine-rich repeat 548..571 CDD:275380
LRR_8 572..630 CDD:290566
leucine-rich repeat 572..595 CDD:275380
leucine-rich repeat 596..619 CDD:275380
LRR_8 619..678 CDD:290566 2/6 (33%)
leucine-rich repeat 620..643 CDD:275380
leucine-rich repeat 644..667 CDD:275380
LRR_8 666..726 CDD:290566 21/54 (39%)
leucine-rich repeat 668..691 CDD:275380 6/19 (32%)
leucine-rich repeat 692..715 CDD:275380 9/22 (41%)
LRR_8 714..774 CDD:290566 9/59 (15%)
leucine-rich repeat 716..739 CDD:275380 5/22 (23%)
leucine-rich repeat 740..761 CDD:275380 3/20 (15%)
leucine-rich repeat 764..789 CDD:275380 3/24 (13%)
leucine-rich repeat 790..810 CDD:275380 0/19 (0%)
leucine-rich repeat 818..850 CDD:275380 9/31 (29%)
leucine-rich repeat 863..883 CDD:275378 8/23 (35%)
LRR_RI <878..1070 CDD:238064 57/201 (28%)
LRR_8 884..944 CDD:290566 20/64 (31%)
LRR_4 884..925 CDD:289563 18/45 (40%)
leucine-rich repeat 884..907 CDD:275380 9/27 (33%)
leucine-rich repeat 908..933 CDD:275380 10/24 (42%)
leucine-rich repeat 934..955 CDD:275380 1/20 (5%)
leucine-rich repeat 958..982 CDD:275380 8/23 (35%)
leucine-rich repeat 983..1055 CDD:275380 21/72 (29%)
leucine-rich repeat 1009..1033 CDD:275380 7/24 (29%)
leucine-rich repeat 1058..1085 CDD:275380 7/31 (23%)
TPKR_C2 1121..1168 CDD:301599 9/60 (15%)
Lrrn4NP_796277.2 LRR 1 62..82 4/15 (27%)
LRR <63..292 CDD:227223 86/356 (24%)
leucine-rich repeat 63..83 CDD:275380 4/16 (25%)
LRR 2 83..106 10/25 (40%)
leucine-rich repeat 84..107 CDD:275380 10/25 (40%)
LRR 3 107..128 7/37 (19%)
leucine-rich repeat 108..130 CDD:275380 7/38 (18%)
LRR 4 130..151 13/96 (14%)
leucine-rich repeat 131..154 CDD:275380 12/87 (14%)
LRR 5 154..175 8/21 (38%)
leucine-rich repeat 155..178 CDD:275380 8/23 (35%)
LRR 6 178..199 8/20 (40%)
leucine-rich repeat 179..207 CDD:275380 9/27 (33%)
LRR 7 207..230 11/48 (23%)
leucine-rich repeat 208..231 CDD:275380 12/48 (25%)
LRR 8 231..253 7/21 (33%)
leucine-rich repeat 232..256 CDD:275380 8/23 (35%)
LRR 9 256..278 7/22 (32%)
leucine-rich repeat 257..281 CDD:275380 6/24 (25%)
LRR 10 281..302 7/25 (28%)
leucine-rich repeat 303..315 CDD:275378 3/13 (23%)
Herpes_TAF50 <347..541 CDD:308764 41/202 (20%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 395..423 7/36 (19%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 480..518 9/39 (23%)
fn3 578..657 CDD:365830
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 47 1.000 Domainoid score I12022
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.910

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