Protein Alignment CG7896 and Islr2

DIOPT Version :10

• Sequence 1: NP_651754.1
• Gene: CG7896 / 43552
• FlyBaseID: FBgn0039728
• Length: 1392
• Species: Drosophila melanogaster
• Sequence 2: NP_001155007.1
• Gene: Islr2 / 320563
• MGIID: 2444277
• Length: 789
• Species: Mus musculus
• Alignment Length: 207
• Identity: 61/207 - (29%)
• Similarity: 97/207 - (46%)
• Gaps: 29/207 - (14%)

  Fly   329 SLESLDISRNTITTITPGTFREMGALKYLDLSLNSLRTIEDDALEGLDSLQTLIIKDNNILLVPG 393
            ::.:|.:|.|.||.:..|.|..:..:..|.|:.:.:||:|..||..|..|:.|.:..|.|...|.
Mouse    96 NVTTLSLSANKITVLRRGAFVNVTQVTSLWLAHSEVRTVESGALAVLSQLKNLDLSHNLISNFPW 160

  Fly   394 SALGRLPQLTSLQLDYNRVAALSAEILGSLQAGDITTLSLSRNVIRELPPGSFQMFSSLHTLDLS 458
            |.|..|..|..|::::||:.:|..:.||:|.  |:.:|.::.|.:|.|.||:|...|:|..|.|.
Mouse   161 SDLRNLSALQLLKMNHNRLGSLPRDALGALP--DLRSLRINNNRLRTLEPGTFDALSALSHLQLY 223

  Fly   459 GN----SLAVINADTFAGLESTLMALK---------------LSQNRLTGLGGAPWVLPELRSLD 504
            .|    |..::....:|.  ||.::|.               :..:||..|..||   |.:|
Mouse   224 HNPFHCSCGLVWLQAWAA--STRVSLPEPDSIACASPPELQGVPVHRLPALPCAP---PSVR--- 280

  Fly   505 LSGNTLTELPST 516
            ||.....|.|.|
Mouse   281 LSAEPPPEAPGT 292

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7896	NP_651754.1	PRK15370	20..>410	CDD:185268	25/80 (31%)
		leucine-rich repeat	109..132	CDD:275380
		leucine-rich repeat	133..161	CDD:275380
		leucine-rich repeat	162..185	CDD:275380
		leucine-rich repeat	186..209	CDD:275380
		leucine-rich repeat	210..233	CDD:275380
		leucine-rich repeat	234..257	CDD:275380
		PLN00113	237..>750	CDD:215061	61/207 (29%)
		leucine-rich repeat	258..281	CDD:275380
		leucine-rich repeat	282..329	CDD:275380	61/207 (29%)
		leucine-rich repeat	330..353	CDD:275380	7/22 (32%)
		leucine-rich repeat	354..377	CDD:275380	8/22 (36%)
		leucine-rich repeat	378..401	CDD:275380	8/22 (36%)
		leucine-rich repeat	402..425	CDD:275380	8/22 (36%)
		leucine-rich repeat	428..451	CDD:275380	7/22 (32%)
		leucine-rich repeat	452..473	CDD:275380	6/24 (25%)
		leucine-rich repeat	477..497	CDD:275378	6/34 (18%)
		leucine-rich repeat	500..523	CDD:275380	6/17 (35%)
		leucine-rich repeat	524..547	CDD:275380
		leucine-rich repeat	548..571	CDD:275380
		leucine-rich repeat	572..595	CDD:275380
		leucine-rich repeat	596..619	CDD:275380
		leucine-rich repeat	620..643	CDD:275380
		leucine-rich repeat	644..667	CDD:275380
		leucine-rich repeat	668..691	CDD:275380
		LRR	<684..1020	CDD:443914
		leucine-rich repeat	692..715	CDD:275380
		leucine-rich repeat	716..739	CDD:275380
		leucine-rich repeat	740..761	CDD:275380
		leucine-rich repeat	764..789	CDD:275380
		leucine-rich repeat	790..810	CDD:275380
		leucine-rich repeat	818..850	CDD:275380
		leucine-rich repeat	863..883	CDD:275378
		leucine-rich repeat	884..907	CDD:275380
		leucine-rich repeat	908..933	CDD:275380
		leucine-rich repeat	934..955	CDD:275380
		leucine-rich repeat	958..982	CDD:275380
		leucine-rich repeat	983..1055	CDD:275380
		leucine-rich repeat	1009..1033	CDD:275380
		leucine-rich repeat	1058..1085	CDD:275380
		LRRCT	1121..1168	CDD:214507
Islr2	NP_001155007.1	leucine-rich repeat	80..96	CDD:275380	61/207 (29%)
		LRR	<95..>227	CDD:443914	44/132 (33%)
		leucine-rich repeat	97..120	CDD:275380	7/22 (32%)
		leucine-rich repeat	121..144	CDD:275380	8/22 (36%)
		leucine-rich repeat	145..168	CDD:275380	8/22 (36%)
		leucine-rich repeat	169..192	CDD:275380	8/24 (33%)
		leucine-rich repeat	193..216	CDD:275380	7/22 (32%)
		PCC	198..>272	CDD:188093	18/75 (24%)
		Ig_3	276..404	CDD:464046	8/23 (35%)
		Ig	<395..417	CDD:472250