Protein Alignment CG7896 and lron-6

DIOPT Version :10

• Sequence 1: NP_651754.1
• Gene: CG7896 / 43552
• FlyBaseID: FBgn0039728
• Length: 1392
• Species: Drosophila melanogaster
• Sequence 2: NP_491851.3
• Gene: lron-6 / 185427
• WormBaseID: WBGene00018157
• Length: 594
• Species: Caenorhabditis elegans
• Alignment Length: 488
• Identity: 124/488 - (25%)
• Similarity: 195/488 - (39%)
• Gaps: 108/488 - (22%)

  Fly   355 KYLDLSLNSLRTI-EDDALEGLDSLQTLIIKDNNILLVPGSALGRLPQ-LTSL----------QL 407
            |:||...|||..| ....|...|:..|::|:::|..|.....||...: :|||          .:
 Worm    78 KWLDHKPNSLPMICRQPNLPNPDAPYTIVIENSNESLTHSFLLGSCSKTVTSLTFQHYHKLYDSI 142

  Fly   408 DYN----RVAALSAEIL--------GSLQ------------------------AGDITTLSLSRN 436
            |:.    |:|:....:|        |||:                        ...||.:.:..:
 Worm   143 DFGECFPRLASFQVVLLQRTKANFHGSLRNLKNLKVLSLVNVDFDFWLQPSPFINTITYIHIENS 207

  Fly   437 VIRELPPGSFQMFSSLHTLDLSGNSLAVINADTFAGLESTLMALKLSQNRLTGLGGAPWVLPELR 501
            .|.|||.. .....||.|:.|.|.|::.:   |.......:.:||||.|.:..|....:|.|.|.
 Worm   208 SITELPKW-LSTSKSLSTVYLKGTSISSL---TPVAQLPAVKSLKLSHNLIENLHRLLFVSPFLI 268

  Fly   502 SLDLSGNTLTELPSTIFEELENVQSLNLSGNHLTPLTGALFKPLD---RLQVIDLSGCNIRQISG 563
            .:|||.|.:|...|..|.:..:::.|:|:||   |:....:||..   :|:.:.||..||..::.
 Worm   269 HVDLSYNQITSFASHTFSKCIDLRVLDLTGN---PIKMLPYKPFAKNIKLKWLKLSRTNITTLTP 330

  Fly   564 DLLAGLQDLKHIYLNDNQLQELQDGSFVNLWNISSIDLSNNRIGSIRSGAFVNVMKLQKLDLHGN 628
            |...||..||.:.|:...:|.:...|||.|.::..:|:.:..:..|......| ..|.:|::..|
 Worm   331 DHFYGLNALKTLSLSRMPIQSISPYSFVPLKSLRYLDMDSCNLTKIPQAVTAN-CHLARLNVANN 394

  Fly   629 QL---SAFKGEYFNTGTGIEELDISDNQLSYLFPSSFRIHPR-------------------LRE- 670
            .|   |:...|.....:|:.:|.|..|.|:. ||:||.:..|                   |||
 Worm   395 MLHRSSSMPPEVMAMLSGLSQLRIEGNPLTE-FPASFLLISRENFRLLRQLLHSTMTLPVWLREP 458

  Fly   671 ----------IRAANNKFSFF-----PAELISTLQYL-EHIDLSHNQLKTIEELD----FARLPR 715
                      ....||..||.     ...|.|.|.|. |..|....|::...||:    ...|.|
 Worm   459 CTPYYWSMHLANRTNNLKSFVNQYSEMRMLKSGLGYCKEQYDWMLEQMEVYRELEKNSGCYSLRR 523

  Fly   716 LRVLLVANNQLDMVSEMAFHNSTQLQILDLAHN 748
            ||..| ::..:..:|:    |||...||.:.|:
 Worm   524 LRSSL-SSKPVPKISK----NSTNSLILSIPHD 551

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7896	NP_651754.1	PRK15370	20..>410	CDD:185268	19/66 (29%)
		leucine-rich repeat	109..132	CDD:275380
		leucine-rich repeat	133..161	CDD:275380
		leucine-rich repeat	162..185	CDD:275380
		leucine-rich repeat	186..209	CDD:275380
		leucine-rich repeat	210..233	CDD:275380
		leucine-rich repeat	234..257	CDD:275380
		PLN00113	237..>750	CDD:215061	124/488 (25%)
		leucine-rich repeat	258..281	CDD:275380
		leucine-rich repeat	282..329	CDD:275380
		leucine-rich repeat	330..353	CDD:275380
		leucine-rich repeat	354..377	CDD:275380	8/22 (36%)
		leucine-rich repeat	378..401	CDD:275380	6/22 (27%)
		leucine-rich repeat	402..425	CDD:275380	10/68 (15%)
		leucine-rich repeat	428..451	CDD:275380	6/22 (27%)
		leucine-rich repeat	452..473	CDD:275380	6/20 (30%)
		leucine-rich repeat	477..497	CDD:275378	6/19 (32%)
		leucine-rich repeat	500..523	CDD:275380	8/22 (36%)
		leucine-rich repeat	524..547	CDD:275380	7/25 (28%)
		leucine-rich repeat	548..571	CDD:275380	8/22 (36%)
		leucine-rich repeat	572..595	CDD:275380	8/22 (36%)
		leucine-rich repeat	596..619	CDD:275380	3/22 (14%)
		leucine-rich repeat	620..643	CDD:275380	6/25 (24%)
		leucine-rich repeat	644..667	CDD:275380	8/22 (36%)
		leucine-rich repeat	668..691	CDD:275380	10/38 (26%)
		LRR	<684..1020	CDD:443914	21/70 (30%)
		leucine-rich repeat	692..715	CDD:275380	6/27 (22%)
		leucine-rich repeat	716..739	CDD:275380	6/22 (27%)
		leucine-rich repeat	740..761	CDD:275380	3/9 (33%)
		leucine-rich repeat	764..789	CDD:275380
		leucine-rich repeat	790..810	CDD:275380
		leucine-rich repeat	818..850	CDD:275380
		leucine-rich repeat	863..883	CDD:275378
		leucine-rich repeat	884..907	CDD:275380
		leucine-rich repeat	908..933	CDD:275380
		leucine-rich repeat	934..955	CDD:275380
		leucine-rich repeat	958..982	CDD:275380
		leucine-rich repeat	983..1055	CDD:275380
		leucine-rich repeat	1009..1033	CDD:275380
		leucine-rich repeat	1058..1085	CDD:275380
		LRRCT	1121..1168	CDD:214507
lron-6	NP_491851.3	LRR	158..478	CDD:443914	80/328 (24%)
		leucine-rich repeat	200..221	CDD:275380	5/21 (24%)
		leucine-rich repeat	222..243	CDD:275380	6/23 (26%)
		leucine-rich repeat	244..265	CDD:275380	7/20 (35%)
		leucine-rich repeat	267..290	CDD:275380	8/22 (36%)
		leucine-rich repeat	291..314	CDD:275380	7/25 (28%)
		leucine-rich repeat	315..338	CDD:275380	8/22 (36%)
		leucine-rich repeat	339..362	CDD:275380	8/22 (36%)
		leucine-rich repeat	363..385	CDD:275380	3/22 (14%)
		leucine-rich repeat	386..412	CDD:275380	6/25 (24%)