Protein Alignment CG7896 and lron-1

DIOPT Version :10

• Sequence 1: NP_651754.1
• Gene: CG7896 / 43552
• FlyBaseID: FBgn0039728
• Length: 1392
• Species: Drosophila melanogaster
• Sequence 2: NP_510424.4
• Gene: lron-1 / 181553
• WormBaseID: WBGene00008093
• Length: 607
• Species: Caenorhabditis elegans
• Alignment Length: 448
• Identity: 116/448 - (25%)
• Similarity: 191/448 - (42%)
• Gaps: 77/448 - (17%)

  Fly   200 PTNSLNGP---SALRHLSLRQN-----QIGSLLADSFNAQRQLEIIDLRHNVIRSIDSLAFKGLQ 256
            ||..|..|   ::.|:.::..|     .:.::|....|:.:.::.:.:.:..|..:...||:|.|
 Worm    19 PTLQLQEPCTCTSTRYEAVSINCDGGSSLDAVLESLSNSPQAIDSLTISNTPIEKMPGYAFQGFQ 83

  Fly   257 KIREIKLAGN--RISHLNSDVFEKLQSLQKLDLSENFFGQFPTVALAAVPGLKHLNLSSNMLQQL 319
             |:::.|..|  |..|.|:.......||::|::..|:....|...::.:..||.|:|..|:   :
 Worm    84 -IKKLFLRNNGLRSFHPNTFTGNLENSLEELEIRGNYIDGIPQSGVSILKQLKILSLPDNL---I 144

  Fly   320 DYTHMQVVRSLESLDISRNTITTITPGTFREMGALKYLDLSLNSLRTIEDDALEGLDSLQTLIIK 384
            :|.......|..|.|                  :|..||||.|:|..|....|.||::|..|.:.
 Worm   145 EYVQDNAFLSYHSRD------------------SLLKLDLSANNLTAIHPTGLLGLENLSQLSLD 191

  Fly   385 DNNILLVPGSALGRLPQLTSLQLDYNRVAALSAEILGSLQAGDITTLSLSRNVIRELPPGSFQMF 449
            .|.:..:|..||..:|.|..|.|..||:..:|.   .||...::.:|||..|.||.:|..||...
 Worm   192 KNLLSEIPSQALENIPSLEDLSLGVNRIHTISR---NSLPLPNLKSLSLEVNQIRLIPSDSFSET 253

  Fly   450 SSLHTLDLSGNSLAVINADTFAGLESTLMALKLSQNRLTGLGGAPWVLPELRSLDLSGNTLTELP 514
            ..|..|.|..|.|..|:|..|..: ..|..|.:|.|:            ::.|:..:|..
 Worm   254 PLLSYLYLGNNLLTSIDASMFLHI-GGLKVLSMSNNK------------DITSIQANGKL----- 300

  Fly   515 STIFEELENVQSLN-----LSGNHLTPLTGALFKPLDRLQVIDLSGCNIRQISGDLLAGLQDLKH 574
                    :||...     |:..|...|.        ||::.|   |:|.:|....|..:|.::.
 Worm   301 --------SVQQFKLCICILAFQHAPSLI--------RLELFD---CSISRIEPKSLQKVQHIQV 346

  Fly   575 IYLNDNQLQELQDGSFVNLWNISSIDLSNNRIGSIRSGAFVNVMKLQKLDLHGNQLSA 632
            |.|:.||:..:...:|.||..:|.:|||.|.|.::...||..:..|..|||..|:|.:
 Worm   347 ILLSRNQITRISHDTFSNLPELSELDLSGNSINAVDDFAFSQLPMLTSLDLSSNRLES 404

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7896	NP_651754.1	PRK15370	20..>410	CDD:185268	54/219 (25%)
		leucine-rich repeat	109..132	CDD:275380
		leucine-rich repeat	133..161	CDD:275380
		leucine-rich repeat	162..185	CDD:275380
		leucine-rich repeat	186..209	CDD:275380	4/11 (36%)
		leucine-rich repeat	210..233	CDD:275380	4/27 (15%)
		leucine-rich repeat	234..257	CDD:275380	4/22 (18%)
		PLN00113	237..>750	CDD:215061	108/403 (27%)
		leucine-rich repeat	258..281	CDD:275380	6/24 (25%)
		leucine-rich repeat	282..329	CDD:275380	10/46 (22%)
		leucine-rich repeat	330..353	CDD:275380	2/22 (9%)
		leucine-rich repeat	354..377	CDD:275380	11/22 (50%)
		leucine-rich repeat	378..401	CDD:275380	6/22 (27%)
		leucine-rich repeat	402..425	CDD:275380	8/22 (36%)
		leucine-rich repeat	428..451	CDD:275380	9/22 (41%)
		leucine-rich repeat	452..473	CDD:275380	8/20 (40%)
		leucine-rich repeat	477..497	CDD:275378	4/19 (21%)
		leucine-rich repeat	500..523	CDD:275380	2/22 (9%)
		leucine-rich repeat	524..547	CDD:275380	5/27 (19%)
		leucine-rich repeat	548..571	CDD:275380	6/22 (27%)
		leucine-rich repeat	572..595	CDD:275380	7/22 (32%)
		leucine-rich repeat	596..619	CDD:275380	8/22 (36%)
		leucine-rich repeat	620..643	CDD:275380	6/13 (46%)
		leucine-rich repeat	644..667	CDD:275380
		leucine-rich repeat	668..691	CDD:275380
		LRR	<684..1020	CDD:443914
		leucine-rich repeat	692..715	CDD:275380
		leucine-rich repeat	716..739	CDD:275380
		leucine-rich repeat	740..761	CDD:275380
		leucine-rich repeat	764..789	CDD:275380
		leucine-rich repeat	790..810	CDD:275380
		leucine-rich repeat	818..850	CDD:275380
		leucine-rich repeat	863..883	CDD:275378
		leucine-rich repeat	884..907	CDD:275380
		leucine-rich repeat	908..933	CDD:275380
		leucine-rich repeat	934..955	CDD:275380
		leucine-rich repeat	958..982	CDD:275380
		leucine-rich repeat	983..1055	CDD:275380
		leucine-rich repeat	1009..1033	CDD:275380
		leucine-rich repeat	1058..1085	CDD:275380
		LRRCT	1121..1168	CDD:214507
lron-1	NP_510424.4	LRR	83..>400	CDD:443914	102/378 (27%)
		leucine-rich repeat	85..109	CDD:275380	5/23 (22%)
		leucine-rich repeat	110..133	CDD:275380	4/22 (18%)
		leucine-rich repeat	134..157	CDD:275380	7/25 (28%)
		leucine-rich repeat	161..184	CDD:275380	11/22 (50%)
		leucine-rich repeat	185..208	CDD:275380	6/22 (27%)
		leucine-rich repeat	209..231	CDD:275380	8/24 (33%)
		leucine-rich repeat	232..255	CDD:275380	9/22 (41%)
		leucine-rich repeat	256..279	CDD:275380	8/23 (35%)
		leucine-rich repeat	280..319	CDD:275380	10/63 (16%)
		leucine-rich repeat	320..343	CDD:275380	8/33 (24%)
		leucine-rich repeat	344..367	CDD:275380	7/22 (32%)
		leucine-rich repeat	368..391	CDD:275380	8/22 (36%)
		leucine-rich repeat	392..410	CDD:275380	6/13 (46%)
		leucine-rich repeat	414..435	CDD:275378
		LRRCT	431..>472	CDD:214507