Protein Alignment CG7896 and LOC1270408

DIOPT Version :10

• Sequence 1: NP_651754.1
• Gene: CG7896 / 43552
• FlyBaseID: FBgn0039728
• Length: 1392
• Species: Drosophila melanogaster
• Sequence 2: XP_061508553.1
• Gene: LOC1270408 / 1270408
• VectorBaseID: AGAMI1_008706
• Length: 1403
• Species: Anopheles gambiae
• Alignment Length: 1431
• Identity: 664/1431 - (46%)
• Similarity: 905/1431 - (63%)
• Gaps: 88/1431 - (6%)

  Fly    14 LLLLLACIAHLGHPILAWRPCPELSPALRLPCRCNVVPFAATGQLGAVAMDCDRVVFHGDAPQLP 78
            |||||||.  |.....|||||.:|...|::|||||:.......|...|.::|||...  .|| .|
Mosquito     9 LLLLLACA--LASVSCAWRPCTDLDALLKIPCRCNIETAGNNSQYVFVNVNCDRTTL--TAP-FP 68

  Fly    79 YGAPIVAYTQRHSGQQVLPAQTFGQLKLTIEELDLSYNLIRRIPEKA-FDGLKDSLNELRLANNL 142
            .|.||::::||:||.|.||..:.  |...:.:||.|.|.:|.|..|| |..|.:.|.||||||||
Mosquito    69 SGIPIISFSQRNSGHQALPDLSI--LNAPVRKLDFSNNALRSIGTKALFGSLAEYLTELRLANNL 131

  Fly   143 LGDNLNPIFSTAELHVLKNLRLLDLSGNKIKLIEEGLLKGCMDLKEFYIDRNSLTSVPTNSLNGP 207
            |||:|||||||..|..|::|::||||||:|..:||.:..|...|.|.|:|:|.:.:||..::...
Mosquito   132 LGDSLNPIFSTDVLQALQSLKVLDLSGNRIIALEESIFDGNRRLVELYLDQNKIATVPVAAVKEL 196

  Fly   208 SALRHLSLRQNQIGSLLADSFNAQRQLEIIDLRHNVIRSIDSLAFKGLQKIREIKLAGNRISHLN 272
            ::|:.||||.|:|.||..|:||...:||.:|||:|.||::.|.||..|..::|:.||||::||::
Mosquito   197 TSLKLLSLRSNRIESLEPDAFNFANKLERLDLRNNRIRTLKSKAFANLASMKEVLLAGNQLSHID 261

  Fly   273 SDVFEKLQSLQKLDLSENFFGQFPTVALAAVPGLKHLNLSSNMLQQLDYTHMQVVRSLESLDISR 337
            ......:..|||||||:|...:||:.||.:|..||.||:|.|.:.:|:..|:..::||:.|||||
Mosquito   262 ERALAGMDVLQKLDLSDNLLSEFPSEALGSVVSLKVLNISLNNIGKLESNHLAQMKSLQILDISR 326

  Fly   338 NTITTITPGTFREMGALKYLDLSLNSLRTIEDDALEGLDSLQTLIIKDNNILLVPGSALGRLPQL 402
            |||.||.||||||...||||||||||||||||||.||||:|||||::|||||.:|||||||||:|
Mosquito   327 NTIATILPGTFREQLLLKYLDLSLNSLRTIEDDAFEGLDNLQTLILRDNNILFIPGSALGRLPKL 391

  Fly   403 TSLQLDYNRVAALSAEILGSLQAGDITTLSLSRNVIRELPPGSFQMFSSLHTLDLSGNSLAVINA 467
            ::|.||:|||||||:.||.|:|..:|..||||||||||||..||..|..|..||:|||||.||..
Mosquito   392 SNLYLDFNRVAALSSSILKSIQPENIRYLSLSRNVIRELPGDSFAAFRKLIYLDISGNSLGVIGE 456

  Fly   468 DTFAGLESTLMALKLSQNRLTGLGGAPWVLPELRSLDLSGNTLTELPSTIFEELENVQSLNLSGN 532
            |||.|||.||:.:|||.||:..|  ..:|||:||.||||.|::.:|....|..|.|:..||:|||
Mosquito   457 DTFKGLEGTLLEIKLSFNRIASL--RKFVLPKLRRLDLSANSIDDLAIDSFHSLHNLLYLNMSGN 519

  Fly   533 -HLTPLTGALFKPLDRLQVIDLSGCNIRQISGDLLAGLQDLKHIYLNDNQLQELQDGSFVNLWNI 596
             |:..:|..:..||.:|||||||.|.::.:..||.....||:...||.|||:.:::|:|:||.|:
Mosquito   520 EHVGQVTRTMIYPLTKLQVIDLSHCGLKMLQADLFHNNTDLRIALLNHNQLRVIEEGTFLNLNNL 584

  Fly   597 SSIDLSNNRIGSIRSGAFVNVMKLQKLDLHGNQLSAFKGEYFNTGTGIEELDISDNQLSYLFPSS 661
            ..:.|:.|.:..:|..:|||.:.|:.|:|..|.|...:.:.|.|.|.:|.||.|||.|.....::
Mosquito   585 FDLSLAGNGLEQLRPRSFVNTVNLRTLNLRQNALQELRADMFTTETALEVLDASDNALKSFATNT 649

  Fly   662 FRIHPRLREIRAANNKFSFFPAELISTLQYLEHIDLSHNQLKTIEELDFARLPRLRVLLVANNQL 726
            .:||||||::..|||:...||.|||:.|.:||.|||:.|:|.||::|||.||..||.|.:..|.:
Mosquito   650 LKIHPRLRKVLLANNRLEVFPPELIADLDHLEVIDLAGNRLTTIQQLDFGRLANLRELYLRANAI 714

  Fly   727 DMVSEMAFHNSTQLQILDLAHNNLDRIGERTFEGLVRLEQLNLEGNRLSELSDGVFERTKLQMLE 791
            |.|.:||||||:||||||||.|.|:|:.||:|||.:||::|:|..|:|:.|.:.|..::::|.||
Mosquito   715 DSVQDMAFHNSSQLQILDLAANRLERLSERSFEGTLRLDRLDLSDNKLTGLPEQVLAKSRVQRLE 779

  Fly   792 NINLAHNRFEYAPLNALQRQFFFVSSVDLSHNKIKELP-GDDSIMVNIKRIDLSFNPLSSKAVHN 855
            .::||.|:....|:.|...|...:.::|||.|.|:|:| ....:|:|.|.:|.|:||||.:|:..
Mosquito   780 RVSLAGNKLASVPVAAFGDQHDTLQTLDLSRNAIREVPRASHMLMINAKHVDFSYNPLSPEAIAT 844

  Fly   856 VLNEPKTVRELSLAGTGIENLELLETPFLQFLNLSHNKLKNVKPEVFQRVTLLETLDLSSNQLES 920
            ||.:|||||.|:|||||:..|.:||||:|:.||||:|.:..|..:.|::|||||.||||.|.:..
Mosquito   845 VLGQPKTVRTLNLAGTGVRELPMLETPYLRSLNLSYNNISAVSAKAFEKVTLLERLDLSHNAIGD 909

  Fly   921 LEDLSMAWPQLQVLQSLDVSNNSFEIVSQSNFGKLEMLRSLRLSHLPQCTRIEKNAFKQLPNLVS 985
            .:.|...||:|.:|..||:|:|....::.|.|.:|:.|..|.:..||:.||:||||||.|.:|..
Mosquito   910 ADGLRDIWPKLALLGYLDLSSNPIRTITASTFERLDGLTELYIRELPELTRLEKNAFKPLKDLTV 974

  Fly   986 LEAYDLPLLGYLDLQGILELLPGLEVLDIEVKDSSIGSEQIQPLKHPRLKSLGIRGDRLKSISSG 1050
            |:||....|||:|:|||::.||.|..:|||.||:::.|:|:|.|.||:|.:||:.|..|:|:|||
Mosquito   975 LQAYQFAKLGYIDVQGIVQELPALAAVDIEAKDANLESDQLQVLHHPKLHTLGLHGYALQSLSSG 1039

  Fly  1051 TLAGLKSNDLSVQLRNTSLNALPPALLFPVPRSSHLSLNVEGSKITVLVPQFLNALEDRRASLQL 1115
            ..|||::..|:|:|.||||.|||||||.|:|||:|:..::.|||:..|...||::|:||:.|:|:
Mosquito  1040 AFAGLRNKYLTVRLHNTSLTALPPALLLPLPRSAHIDFSIAGSKVGTLTQPFLSSLDDRKNSIQI 1104

  Fly  1116 QGLASNPIVCDCNARALRRWLPSSGMPDVTCASPAYLLNRKLIEVGDDELTCDARRMTSSTSRPT 1180
            .|||:||:.|||.|||.|||:.::.:.||.||||..:..:.|.||||.||.||.|...:|.::|.
Mosquito  1105 DGLATNPVRCDCQARAFRRWILATKVQDVRCASPPTVAGKLLTEVGDSELVCDGRSKATSPTQPA 1169

  Fly  1181 AS-----------VPHLLKTSSQLVTRSSSTTEEPLIIWSLEPTQPPS----LKKMKTKA----- 1225
            ||           :.....||...:|.:::|||.. ||||:.|....|    .|..|:|.
Mosquito  1170 ASSTGGSTRTTPTISFYNYTSEVQMTNAAATTEHD-IIWSMPPVSSSSTTTRTKGSKSKVSSAAM 1233

  Fly  1226 -PLMKAQSPIISNDDTLIIGIVGGVVAFIAILIIIICIIRLRMSNAEYQQNATMIGIPAGMQM-G 1288
             ||.|..|   :||||||||||||||.||.:|||.|||.||:|:|..|..:....|.|..|.| |
Mosquito  1234 PPLKKMPS---ANDDTLIIGIVGGVVVFIFLLIICICICRLKMNNDSYHHHHARAGHPMPMGMPG 1295

  Fly  1289 AHNAAYNYKNGAGAALY--AVPPY---HATLPHKA-----------ASIHQ-----------SSQ 1326
            .....|..|.|..||:|  ..|||   :||||:|.           ::|.:           |||
Mosquito  1296 TLQVNYTGKKGQPAAMYPTLAPPYAQSYATLPYKPNGSPTQARPSYSTIGRIPYQYQNHTLMSSQ 1360

  Fly  1327 NLSQRQQQQQQQQQVAAAAAAYSTMSRMSYFSGAGGGNGDGAESLTHQHPHQHQPYIIYSDDKAY 1391
            .....||||||..|..|...:..|                    |||.   .|.|||:|.|||.|
Mosquito  1361 AALHHQQQQQQHAQQHAQQQSSGT--------------------LTHS---AHNPYIVYQDDKVY 1402

  Fly  1392 R 1392
            |
Mosquito  1403 R 1403

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7896	NP_651754.1	PRK15370	20..>410	CDD:185268	197/390 (51%)
		leucine-rich repeat	109..132	CDD:275380	10/23 (43%)
		leucine-rich repeat	133..161	CDD:275380	21/27 (78%)
		leucine-rich repeat	162..185	CDD:275380	11/22 (50%)
		leucine-rich repeat	186..209	CDD:275380	7/22 (32%)
		leucine-rich repeat	210..233	CDD:275380	12/22 (55%)
		leucine-rich repeat	234..257	CDD:275380	12/22 (55%)
		PLN00113	237..>750	CDD:215061	268/513 (52%)
		leucine-rich repeat	258..281	CDD:275380	7/22 (32%)
		leucine-rich repeat	282..329	CDD:275380	21/46 (46%)
		leucine-rich repeat	330..353	CDD:275380	17/22 (77%)
		leucine-rich repeat	354..377	CDD:275380	21/22 (95%)
		leucine-rich repeat	378..401	CDD:275380	18/22 (82%)
		leucine-rich repeat	402..425	CDD:275380	14/22 (64%)
		leucine-rich repeat	428..451	CDD:275380	16/22 (73%)
		leucine-rich repeat	452..473	CDD:275380	13/20 (65%)
		leucine-rich repeat	477..497	CDD:275378	7/19 (37%)
		leucine-rich repeat	500..523	CDD:275380	10/22 (45%)
		leucine-rich repeat	524..547	CDD:275380	9/23 (39%)
		leucine-rich repeat	548..571	CDD:275380	10/22 (45%)
		leucine-rich repeat	572..595	CDD:275380	10/22 (45%)
		leucine-rich repeat	596..619	CDD:275380	6/22 (27%)
		leucine-rich repeat	620..643	CDD:275380	7/22 (32%)
		leucine-rich repeat	644..667	CDD:275380	9/22 (41%)
		leucine-rich repeat	668..691	CDD:275380	11/22 (50%)
		LRR	<684..1020	CDD:443914	160/336 (48%)
		leucine-rich repeat	692..715	CDD:275380	14/22 (64%)
		leucine-rich repeat	716..739	CDD:275380	12/22 (55%)
		leucine-rich repeat	740..761	CDD:275380	14/20 (70%)
		leucine-rich repeat	764..789	CDD:275380	7/24 (29%)
		leucine-rich repeat	790..810	CDD:275380	7/19 (37%)
		leucine-rich repeat	818..850	CDD:275380	15/32 (47%)
		leucine-rich repeat	863..883	CDD:275378	12/19 (63%)
		leucine-rich repeat	884..907	CDD:275380	9/22 (41%)
		leucine-rich repeat	908..933	CDD:275380	11/24 (46%)
		leucine-rich repeat	934..955	CDD:275380	7/20 (35%)
		leucine-rich repeat	958..982	CDD:275380	13/23 (57%)
		leucine-rich repeat	983..1055	CDD:275380	35/71 (49%)
		leucine-rich repeat	1009..1033	CDD:275380	11/23 (48%)
		leucine-rich repeat	1058..1085	CDD:275380	18/26 (69%)
		LRRCT	1121..1168	CDD:214507	24/46 (52%)
LOC1270408	XP_061508553.1	None