DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG7896 and lrrn3a

DIOPT Version :9

Sequence 1:NP_651754.1 Gene:CG7896 / 43552 FlyBaseID:FBgn0039728 Length:1392 Species:Drosophila melanogaster
Sequence 2:XP_005163128.1 Gene:lrrn3a / 101887059 ZFINID:ZDB-GENE-061220-7 Length:691 Species:Danio rerio


Alignment Length:766 Identity:165/766 - (21%)
Similarity:303/766 - (39%) Gaps:179/766 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly   362 NSLRTIEDDALEGLDSLQTLIIKDNNILLVPGSALGR-------LPQLTSLQLDYNRVAALSAEI 419
            |...|::.:.| ||.:|...:..|..:||...:::.:       |..||.:.|..|.:::||...
Zfish    48 NEAPTVDCNDL-GLLTLPERLPSDTQVLLSQANSIAKIDSPLDYLVNLTEVDLSRNNISSLSDIY 111

  Fly   420 LGSLQAGDITTLSLSRNVIRELPPGSFQMFSSLHTLDLSGNSLAVINADTFAGLESTLMALKLSQ 484
            :|.:.  .:.:|.|..|.:..|.......|.:|..|.::.|.|::|:|:.|.||.          
Zfish   112 IGHIP--QLLSLHLEENWLSSLHDNFLAHFPNLQELYVNHNLLSLISAEAFQGLN---------- 164

  Fly   485 NRLTGLGGAPWVLPELRSLDLSGNTLTELPSTIFEELENVQSLNLSGNHLTPLTGALFKPLDRLQ 549
                          :|..|.|:.|.|..:.|..|::|..::.|.:..|.:..:....||||..|:
Zfish   165 --------------KLLRLHLNSNQLRAIRSEWFQDLSQLEILMIGENPIARIQNMNFKPLINLR 215

  Fly   550 VIDLSGCNIRQISGDLLAGLQDLKHIYLNDNQLQELQDGSFVNLWNISSIDLSNNRIGSIRSGAF 614
            .:.|:..|:.:|....|.||..|:.:...||...::...:...:.|:..:||:.|.|..|:.|.|
Zfish   216 SLVLTRMNLTEIPDSALVGLDKLESVSFYDNMFPKVPQAALRQVRNLKFLDLNKNPIERIQRGDF 280

  Fly   615 VNVMKLQKLDLHGNQLSAFKGEYFNTGTGIEELDISDNQLSYLFPSSFRIH--PRLREIRAANN- 676
            |:::.|::|.::                .:.||...|         ||.:|  |.|.:|.|.|| 
Zfish   281 VDMIHLKELGIN----------------SMPELVSID---------SFALHNLPELTKIEATNNP 320

  Fly   677 KFSFFPAELISTLQYLEHIDLSHNQLKTIEELDFARLPRLRVLLVANNQL--DMVSEMAFHNSTQ 739
            :.|:......|.|..||.:.|:.|.|:.:..:....||.|:.:.:.:|.:  |.|......|:|:
Zfish   321 RLSYIHPNAFSQLPRLESLMLNSNALRALHHITVESLPNLQEVSIHSNPIYCDCVIRWINMNNTR 385

  Fly   740 LQILDLAHNNLDRIGERTFEG-LVRLEQLNLEGNRLSELSDGVFERTKLQMLENINLAHNRFEYA 803
            ::.::|  :.|...|...||| ||:    .:....::::...:.....|....|:...|      
Zfish   386 VRFMEL--DALLCAGPSEFEGRLVK----QVHSREMADICLPLISPESLPDQVNVGTGH------ 438

  Fly   804 PLNALQRQFFF-----VSSVDLSHNKIKELPGDDSIMVNIKRIDLSFNPLSSKAVHNVL-NEPKT 862
             |.:|..:.|.     :..|..|..||  ||..||     |:..|  :|..:..::.:. ||   
Zfish   439 -LVSLHCRAFADPEPEIYWVTPSGEKI--LPQMDS-----KKYHL--HPEGTFDIYGITENE--- 490

  Fly   863 VRELSLAGTGIENLELLETPFLQFLNLSHN----KLKNVKPEVFQRVTLL--ETLDLSSNQLESL 921
                  ||              |:..::||    .:::|...|.....||  |:|.:   |:|:.
Zfish   491 ------AG--------------QYTCVAHNLIGVDMRSVLVIVNGYYPLLVNESLHI---QVENT 532

  Fly   922 E--DLSMAW--PQLQVLQSLDVSNN----SFEIVSQ--SNFGKLEMLRSLRLSHLPQCTRIEKNA 976
            |  .:|::|  |:..::.::..|.|    |.:..|.  ||..|..:.....|:....|..|....
Zfish   533 EPNSVSISWVPPKGSLVSNIKWSTNSQHHSLQFTSHVVSNVKKFYLTNLHSLTQYEVCVEITDMQ 597

  Fly   977 FKQLPNLVSLEAYDLPLLGYLDL--QGILELLPGLEVLDIEVKDSSIGSEQIQPLKHPRLKSLGI 1039
            .:.|.|.:::...::......|:  .|::..|..:.::                           
Zfish   598 SRHLKNCINVTTTEVSKRKNDDVINDGLIISLTAVLLI--------------------------- 635

  Fly  1040 RGDRLKSISSGTLAGLKSND-LSVQLRNTSLNALPPALLFPVPRSSHLSLN 1089
                :.:::...:..|:.|| |..:|||.....||          ||:..|
Zfish   636 ----MSAVACSFICMLRRNDPLYRKLRNQQSEILP----------SHIKPN 672

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG7896NP_651754.1 LRR_8 109..172 CDD:290566
leucine-rich repeat 109..132 CDD:275380
LRR_RI <132..338 CDD:238064
leucine-rich repeat 133..161 CDD:275380
LRR_8 160..220 CDD:290566
leucine-rich repeat 162..185 CDD:275380
leucine-rich repeat 186..209 CDD:275380
leucine-rich repeat 210..233 CDD:275380
LRR_8 232..290 CDD:290566
leucine-rich repeat 234..257 CDD:275380
leucine-rich repeat 258..281 CDD:275380
LRR_RI 273..535 CDD:238064 41/179 (23%)
LRR_8 281..338 CDD:290566
leucine-rich repeat 282..329 CDD:275380
LRR_8 328..388 CDD:290566 7/25 (28%)
leucine-rich repeat 330..353 CDD:275380
leucine-rich repeat 354..377 CDD:275380 5/14 (36%)
leucine-rich repeat 378..401 CDD:275380 5/29 (17%)
leucine-rich repeat 402..425 CDD:275380 7/22 (32%)
leucine-rich repeat 428..451 CDD:275380 5/22 (23%)
LRR_8 429..487 CDD:290566 14/57 (25%)
leucine-rich repeat 452..473 CDD:275380 7/20 (35%)
leucine-rich repeat 477..497 CDD:275378 0/19 (0%)
LRR_8 498..558 CDD:290566 16/59 (27%)
leucine-rich repeat 500..523 CDD:275380 8/22 (36%)
LRR_RI 502..769 CDD:238064 70/272 (26%)
leucine-rich repeat 524..547 CDD:275380 6/22 (27%)
leucine-rich repeat 548..571 CDD:275380 7/22 (32%)
LRR_8 572..630 CDD:290566 14/57 (25%)
leucine-rich repeat 572..595 CDD:275380 3/22 (14%)
leucine-rich repeat 596..619 CDD:275380 8/22 (36%)
LRR_8 619..678 CDD:290566 14/61 (23%)
leucine-rich repeat 620..643 CDD:275380 2/22 (9%)
leucine-rich repeat 644..667 CDD:275380 6/24 (25%)
LRR_8 666..726 CDD:290566 18/60 (30%)
leucine-rich repeat 668..691 CDD:275380 8/23 (35%)
leucine-rich repeat 692..715 CDD:275380 6/22 (27%)
LRR_8 714..774 CDD:290566 15/62 (24%)
leucine-rich repeat 716..739 CDD:275380 5/24 (21%)
leucine-rich repeat 740..761 CDD:275380 6/21 (29%)
leucine-rich repeat 764..789 CDD:275380 1/24 (4%)
leucine-rich repeat 790..810 CDD:275380 4/19 (21%)
leucine-rich repeat 818..850 CDD:275380 11/31 (35%)
leucine-rich repeat 863..883 CDD:275378 2/19 (11%)
LRR_RI <878..1070 CDD:238064 37/210 (18%)
LRR_8 884..944 CDD:290566 17/73 (23%)
LRR_4 884..925 CDD:289563 12/48 (25%)
leucine-rich repeat 884..907 CDD:275380 5/26 (19%)
leucine-rich repeat 908..933 CDD:275380 9/30 (30%)
leucine-rich repeat 934..955 CDD:275380 6/26 (23%)
leucine-rich repeat 958..982 CDD:275380 4/23 (17%)
leucine-rich repeat 983..1055 CDD:275380 3/73 (4%)
leucine-rich repeat 1009..1033 CDD:275380 0/23 (0%)
leucine-rich repeat 1058..1085 CDD:275380 8/27 (30%)
TPKR_C2 1121..1168 CDD:301599
lrrn3aXP_005163128.1 LRR_RI 29..>272 CDD:238064 59/250 (24%)
leucine-rich repeat 52..70 CDD:275380 5/18 (28%)
leucine-rich repeat 71..93 CDD:275380 3/21 (14%)
leucine-rich repeat 94..117 CDD:275380 7/24 (29%)
leucine-rich repeat 118..141 CDD:275380 5/22 (23%)
LRR_8 140..200 CDD:290566 19/83 (23%)
leucine-rich repeat 142..165 CDD:275380 9/46 (20%)
leucine-rich repeat 166..189 CDD:275380 8/22 (36%)
leucine-rich repeat 190..213 CDD:275380 6/22 (27%)
LRR_8 213..272 CDD:290566 14/58 (24%)
leucine-rich repeat 214..237 CDD:275380 7/22 (32%)
leucine-rich repeat 238..261 CDD:275380 3/22 (14%)
leucine-rich repeat 262..285 CDD:275380 8/22 (36%)
leucine-rich repeat 286..310 CDD:275380 8/48 (17%)
LRR_8 309..370 CDD:290566 18/60 (30%)
leucine-rich repeat 311..333 CDD:275380 7/21 (33%)
leucine-rich repeat 336..359 CDD:275378 6/22 (27%)
leucine-rich repeat 360..372 CDD:275378 2/11 (18%)
LRRCT 368..412 CDD:214507 13/49 (27%)
IG_like 429..513 CDD:214653 24/122 (20%)
Ig 437..513 CDD:299845 23/114 (20%)
FN3 526..>591 CDD:238020 14/67 (21%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24366
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
33.010

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