Protein Alignment CG7896 and mxra5a

DIOPT Version :10

• Sequence 1: NP_651754.1
• Gene: CG7896 / 43552
• FlyBaseID: FBgn0039728
• Length: 1392
• Species: Drosophila melanogaster
• Sequence 2: XP_001919144.4
• Gene: mxra5a / 100151112
• ZFINID: ZDB-GENE-090312-22
• Length: 2516
• Species: Danio rerio
• Alignment Length: 1575
• Identity: 278/1575 - (17%)
• Similarity: 501/1575 - (31%)
• Gaps: 578/1575 - (36%)

  Fly    11 GRF-----LLLLLACIAHLGHPILAWRPCPELSPALRLPCRCNVVPFAATGQLGAVAMDCDRVVF 70
            |||     ::|:|..:     |: |.:.||.       ||.|:          ..|.:.|   .|
Zfish     2 GRFYAQIWIMLMLIAV-----PV-AVQCCPR-------PCACH----------QPVEVHC---TF 40

  Fly    71 HGDAPQLPYGAPIVAYTQRHSGQQVLPAQTFGQLKLTIEELDLSYNLIRRIPEKAFDGLKDSLNE 135
            . ....:|.|.|          :||             |.::|.:|.|.:|...:|.||:..  |
Zfish    41 R-SLLTVPAGVP----------KQV-------------ERMNLGFNTIHKITYSSFAGLRKM--E 79

  Fly   136 LRLANNLLGDNLNPIFSTAELHVLKNLRLLDLSGNKIKLIEEGLLKGCMDLKEFYIDRNSLTSVP 200
            |.|.:   |:|::.| .......|.:|::|.||.||:||:....|.|...|...::|
Zfish    80 LLLMH---GNNVHQI-PDGTFRDLISLQMLKLSYNKLKLLSRQTLMGLWSLTRLHLD-------- 132

  Fly   201 TNSLNGPSALRHLSLRQNQIGSLLADSFNAQRQLEIIDLRHNVIRSIDSLAFKGLQKIREIKLAG 265
                                                    ||.:..|...||:||..:|.:.|.|
Zfish   133 ----------------------------------------HNRLEFIHPDAFQGLTNLRLLHLEG 157

  Fly   266 NRISHLNSDVFEKLQSLQKLDLSENFFGQFPTVALAAVPGLKHLNLSSNMLQQLDYTHMQVVRSL 330
            |::..|:...|.....|:          .||      |..||||.||.|:|..|....:..:..|
Zfish   158 NQLQQLHPATFSTFSVLR----------HFP------VSTLKHLYLSDNILTTLSQKMLASMPYL 206

  Fly   331 ESLDISRNTITTITPGT-------FRE-----MGALKY-------------LDLSLNSLR----- 365
            |||.:..|      |.|       |.|     .|.||.             |..|...|:
Zfish   207 ESLSLHGN------PWTCDCRMRWFNEWNKNSQGVLKCKKDKAYPSGQLCPLCFSPKQLKKKQLQ 265

  Fly   366 ------------TIEDDALEGLDSLQTLIIKD------NNILLVPGSALGRLPQLTSLQLDYNRV 412
                        :|.:.|:...|:...|:..|      .||.|......|....|..|.::...:
Zfish   266 ELEKPTCNSPIISISNRAISSEDTESDLLTMDEFRQPLGNISLGLSDEHGHQVDLECLVIEPREL 330

  Fly   413 AALSAEILGSLQAGDITTLSLS------------------------RNVIRELPPGSFQMFSSLH 453
            .::..:.:...|.....||:|.                        .::.||:........|..:
Zfish   331 TSIGWDYVNQYQISVNLTLTLDLICGIDRSSYERLWRLIAYYSDVPAHLRREIMLSKDPYLSYRY 395

  Fly   454 TLDLSGNSLAVINADTFAGLESTLMALKLSQNRLTGLGGAPWVLPELRSLDLSGNTLTELPSTIF 518
            ..|:..::|      .|.|:::.:.|            ..||::..  |:||.   |..|.||
Zfish   396 RQDIERDAL------YFTGVKANIAA------------NPPWLMQS--SMDLQ---LNRLQST-- 435

  Fly   519 EELENVQSLNLSGNHLTPLTGALFKPLDRLQ----VIDLSGCNIRQISGDLL---AGLQDLKHIY 576
              .:||: |.||    |.:|..:.:...|.|    |:..|..:.|.:...::   |.:....|..
Zfish   436 --SKNVR-LILS----TYMTDVMERETIRKQSQGWVLIESKNDTRTMQAAVVGSPAKINCTVHSS 493

  Fly   577 LNDNQLQELQDGSFVNLWNISSIDLSNNRIGSIRSGAFVNVMKLQKLDLHGNQ------------ 629
            .|::....|.|||.:.    :....|.||:.:..||    :::::.|| |.:.
Zfish   494 GNESVKWMLPDGSTIE----TPYRNSENRLSASSSG----LLEIKSLD-HSDSGVYYCIAQVSDD 549

  Fly   630 --------------------------LSAFKGEYFN---TGTGIEELDISDNQLSYLFPSSFRIH 665
                                      ::.|.||.|:   ..||..:.||     .::.|:...::
Zfish   550 LTVFPFRLTVEESSSPPPGGEGITEPVTGFAGEPFSLPCAATGSPDADI-----HWILPNGSIVN 609

  Fly   666 P--RLREIRAANNKFSFFPAELISTLQYLEHIDLSHNQLKTI-EELDFARLPRLRVLLVANNQLD 727
            .  .:..|..|:|.........:|...|.:.:..:.:.:.|: .:|..:|.|.:..|    .:..
Zfish   610 KWLNISRISVASNGSLVIQNSQLSDNGYYKCVAGNQHGMDTLATKLIISRPPGIPAL----RKYS 670

  Fly   728 MVSEMAFHNSTQLQILDLAHNNLDRIGERTFEGLV--------------RLEQLNLEGNRLSELS 778
            ...:.|...||::.|  |..|:::..|:...|..:              |:..:.:.|...|..|
Zfish   671 SSPQPAEGVSTKINI--LMTNDMESSGDNEPEDFLAKALAKKVEIPNRRRIPNMGIRGGHPSRNS 733

  Fly   779 ----DGVFERTKLQMLENINLAHNRFEYAPLNALQRQFFFVSSVDLSHNKIKELPGDDSIMVNIK 839
                .....|...|:::..|...:|                                       :
Zfish   734 WRQASTPRRRVGTQVIDRANTVDSR---------------------------------------R 759

  Fly   840 RIDLSFNPLSSKAVHNVLNEPKTVRELSLAGTGIENLELLETPFLQFLNLSHNKLKNVKPEVFQR 904
            ||.:..|.:..|...::|::.::                           ..|..|...|...|
Zfish   760 RISMLKNQIDPKHWASILSKVRS---------------------------GGNDTKATTPNYAQ- 796

  Fly   905 VTLLETLDLSSNQLESLEDLSMAWPQLQVLQSLDVSNNSFEIVSQSNFGKLEMLRSLRLSHLPQC 969
                    .|:|:::..|..:   .|.:::..::.|::.|                       ..
Zfish   797 --------TSTNKIQESEQNT---KQSEIVNKIEGSSSEF-----------------------TT 827

  Fly   970 TR--IEKNAFKQLPNLVSLEAYDLPLLGYLDLQGILELLPGLEVLDIEVKDSSIGSEQIQPLKHP 1032
            ||  ::.....|:|:..:....|:..|.|.:.:.::..:...|.    |.:|.:.::..||...|
Zfish   828 TRPPVKDATVSQMPDGATEFNLDIRALDYENTRHVIYQIASPET----VPNSDLFTDITQPTVGP 888

  Fly  1033 RLKSLGIRGDR--LKSISSGTLAGLKSNDLSVQLRNTSLNALPPALLFPVPRSSHLSLNVEGSKI 1095
            ::....: ||.  .|.::..|:....|....:|                 ...||   .::..::
Zfish   889 QMTRFTV-GDSGISKRVAMSTVWSTTSYGTHLQ-----------------ENQSH---TMDSGRV 932

  Fly  1096 TVLVPQFLNALEDRRASLQLQGLASNPIVCDCNARALRRWLPSSGMPDVTCAS---PAYLLNRKL 1157
            |..:.||     |.:..::.:.:.:...|.....|.....|.|:.:..:|..|   ..|.|...|
Zfish   933 TEAIQQF-----DGKYDVENRVVQNQEHVGQVYQRGTDHSLASTTVKSITEPSKETAVYSLTETL 992

  Fly  1158 IEVGDDELTCDARRMT--------------SSTSRPTA------------SVPHLLKTSS----- 1191
            .::.....|.. :.:|              :.|::||:            |..|...|||
Zfish   993 TKIKQGPQTLQ-KHITQEKHVSEIPLILSVTPTTKPTSGRKATFTNSLNVSSSHARNTSSLRRRN 1056

  Fly  1192 --------QLVTRSSSTTEEPLIIWSLEPTQP-----------PSLKK----MKTKAPLMKAQSP 1233
                    ::.||::| ::..|.|..:.| ||           |.:.|    .|||....:|.|
Zfish  1057 GGRRRKTNRVKTRTNS-SKSSLYITDITP-QPNFSSLEVTNGLPVVTKTTASSKTKIETPQANS- 1118

  Fly  1234 IISNDDTLIIGIVGGVVAFIAILIIIICIIRLRMSNAEYQQNA-------------TMIGIPAGM 1285
                           |||.|...:.|..|....:.|..:::|.             ::..:...|
Zfish  1119 ---------------VVAKINTTVPITDIQPPSLGNMTHEKNTNSLYSGRNRKTHKSLSQVKVSM 1168

  Fly  1286 QMGAHNAAY--------------------NYK---------NGAGAAL-YAVPPYHATLPHKAAS 1320
            ....|::.|                    |:|         ||....: :.:||..||:..:..:
Zfish  1169 TKDRHSSNYMSTGEIKSTTAVPVFPSTFSNFKKEQEKQTILNGEKLGVSHHIPPLKATIHEEFTT 1233

  Fly  1321 IHQSSQNLSQRQQQQ 1335
            ||..:..:.:..:|:
Zfish  1234 IHAPAPKIFEETEQE 1248

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7896	NP_651754.1	PRK15370	20..>410	CDD:185268	94/437 (22%)
		leucine-rich repeat	109..132	CDD:275380	8/22 (36%)
		leucine-rich repeat	133..161	CDD:275380	7/27 (26%)
		leucine-rich repeat	162..185	CDD:275380	10/22 (45%)
		leucine-rich repeat	186..209	CDD:275380	2/22 (9%)
		leucine-rich repeat	210..233	CDD:275380	0/22 (0%)
		leucine-rich repeat	234..257	CDD:275380	7/22 (32%)
		PLN00113	237..>750	CDD:215061	125/635 (20%)
		leucine-rich repeat	258..281	CDD:275380	6/22 (27%)
		leucine-rich repeat	282..329	CDD:275380	13/46 (28%)
		leucine-rich repeat	330..353	CDD:275380	9/34 (26%)
		leucine-rich repeat	354..377	CDD:275380	7/52 (13%)
		leucine-rich repeat	378..401	CDD:275380	6/28 (21%)
		leucine-rich repeat	402..425	CDD:275380	2/22 (9%)
		leucine-rich repeat	428..451	CDD:275380	5/46 (11%)
		leucine-rich repeat	452..473	CDD:275380	3/20 (15%)
		leucine-rich repeat	477..497	CDD:275378	3/19 (16%)
		leucine-rich repeat	500..523	CDD:275380	7/22 (32%)
		leucine-rich repeat	524..547	CDD:275380	6/22 (27%)
		leucine-rich repeat	548..571	CDD:275380	5/29 (17%)
		leucine-rich repeat	572..595	CDD:275380	6/22 (27%)
		leucine-rich repeat	596..619	CDD:275380	5/22 (23%)
		leucine-rich repeat	620..643	CDD:275380	7/63 (11%)
		leucine-rich repeat	644..667	CDD:275380	3/24 (13%)
		leucine-rich repeat	668..691	CDD:275380	4/22 (18%)
		LRR	<684..1020	CDD:443914	47/356 (13%)
		leucine-rich repeat	692..715	CDD:275380	3/23 (13%)
		leucine-rich repeat	716..739	CDD:275380	3/22 (14%)
		leucine-rich repeat	740..761	CDD:275380	5/20 (25%)
		leucine-rich repeat	764..789	CDD:275380	4/28 (14%)
		leucine-rich repeat	790..810	CDD:275380	2/19 (11%)
		leucine-rich repeat	818..850	CDD:275380	3/31 (10%)
		leucine-rich repeat	863..883	CDD:275378	0/19 (0%)
		leucine-rich repeat	884..907	CDD:275380	4/22 (18%)
		leucine-rich repeat	908..933	CDD:275380	4/24 (17%)
		leucine-rich repeat	934..955	CDD:275380	2/20 (10%)
		leucine-rich repeat	958..982	CDD:275380	3/25 (12%)
		leucine-rich repeat	983..1055	CDD:275380	13/73 (18%)
		leucine-rich repeat	1009..1033	CDD:275380	5/23 (22%)
		leucine-rich repeat	1058..1085	CDD:275380	1/26 (4%)
		LRRCT	1121..1168	CDD:214507	10/49 (20%)
mxra5a	XP_001919144.4	None