Protein Alignment TkR99D and qrfpr

DIOPT Version :10

• Sequence 1: NP_001263092.1
• Gene: TkR99D / 43551
• FlyBaseID: FBgn0004622
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: XP_012820557.1
• Gene: qrfpr / 779748
• XenbaseID: XB-GENE-994316
• Length: 456
• Species: Xenopus tropicalis
• Alignment Length: 381
• Identity: 102/381 - (26%)
• Similarity: 176/381 - (46%)
• Gaps: 70/381 - (18%)

  Fly   113 IVATGGNLIVVWIVMTTKRMRTVTNYFIVNLSIADAMVSSLNVTFNYYYMLDSDWPFGEFYCKLS 177
            ::|..||.:|:::|..:|.||||||.||.:|:::|.:::...:.|.....:.|:|..|.|.||:.
 Frog    91 VLALFGNSLVLYVVTRSKAMRTVTNIFICSLALSDLLIAFFCIPFTMLQNISSNWLGGAFACKMV 155

  Fly   178 QFIAMLSICASVFTLMAISIDRYVAIIRPLQPR--MSKRCNLAIAAVIWLASTLISCPMMIIYRT 240
            .|:...:|...:.|:..|:::|:..|:.||:.:  .:.|....:..::||.:.::..||....|.
 Frog   156 PFVQSTAIVTEILTMTCIAVERHQGIVHPLKMKWQYTNRRAFTMLGIVWLIAAVVGIPMWHAQRL 220

  Fly   241 EEVPVRGLSNR--TVCYPEWPDGPTNHSTMESLYNILIIILTYFLPIVSMTVTYSRVGIELWGSK 303
             ||....|..:  ..|...|     |....:.:|...|:::.:.||:..|.:.||::|.|||..|
 Frog   221 -EVKYDFLYEKQYVCCLEAW-----NSQVHQKIYTTFILVILFLLPLTVMLLLYSKIGYELWIKK 279

  Fly   304 TIGECTPRQV-------ENVRSKRRVVKMMIVVVLIFAICWLPFH------SYFIITSCYPAITE 355
            .:|:.:..|.       :..|.|:|.:.|||.||::||:||.|||      .|....:.|..:|
 Frog   280 RVGDASVLQTIHGSEMSKIARKKKRAIIMMITVVVLFAVCWAPFHVVHMMIEYSNFENEYDDVT- 343

  Fly   356 APFIQELYLAIYWLAMSNSMYNPIIYCWMNSRFRYGFKMVFRWCLFVRVGTEP------------ 408
               |:.::..:..:...||:.|||:|.:||..|:..|.....:| |:|..:.|
 Frog   344 ---IKIIFAIVQIIGFFNSICNPIVYAFMNENFKKNFLSALCFC-FLRDPSSPSRRPGNSGITLI 404

  Fly   409 -----FSRRENLTSRYSCSGSPDHNRIKRNDTQKSI---------LYTCPSSPKSH 450
                 .|||||     :|           .||::..         .:..|.|.|.|
 Frog   405 QQKSSSSRREN-----TC-----------EDTRREAFSEGNIEVKFFDQPVSKKRH 444

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TkR99D	NP_001263092.1	7tmA_TACR	102..392	CDD:320512	85/295 (29%)
		TM helix 1	103..129	CDD:320512	5/15 (33%)
		TM helix 2	136..162	CDD:320512	7/25 (28%)
		TM helix 3	174..204	CDD:320512	7/29 (24%)
		TM helix 4	215..236	CDD:320512	4/20 (20%)
		TM helix 5	269..298	CDD:320512	8/28 (29%)
		TM helix 6	317..347	CDD:320512	16/35 (46%)
		TM helix 7	360..385	CDD:320512	6/24 (25%)
qrfpr	XP_012820557.1	7tmA_QRFPR	80..377	CDD:320333	85/295 (29%)
		TM helix 1	81..107	CDD:320333	5/15 (33%)
		TM helix 2	114..140	CDD:320333	7/25 (28%)
		TM helix 3	152..182	CDD:320333	7/29 (24%)
		TM helix 4	195..216	CDD:320333	4/20 (20%)
		TM helix 5	245..270	CDD:320333	6/24 (25%)
		TM helix 6	300..330	CDD:320333	15/29 (52%)
		TM helix 7	345..370	CDD:320333	6/24 (25%)