Protein Alignment TkR99D and prlhr2a

DIOPT Version :10

• Sequence 1: NP_001263092.1
• Gene: TkR99D / 43551
• FlyBaseID: FBgn0004622
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_001034615.1
• Gene: prlhr2a / 654782
• ZFINID: ZDB-GENE-060209-1
• Length: 370
• Species: Danio rerio
• Alignment Length: 288
• Identity: 83/288 - (28%)
• Similarity: 142/288 - (49%)
• Gaps: 9/288 - (3%)

  Fly   111 MVIVATGGNLIVVWIVMTTKRMRTVTNYFIVNLSIADAMVSSLNVTFNYYYMLD-SDWPFGEFYC 174
            :|:|...||.::::::..||:|..|||:||.||:.:|.::.:..|.|...|..: ..|.||.|.|
Zfish    68 VVLVGVFGNYLLLYVICQTKKMHNVTNFFIGNLAFSDMLMCATCVPFTLAYAFNPRGWVFGRFMC 132

  Fly   175 KLSQFIAMLSICASVFTLMAISIDRYVAIIRPLQPRMSKRCNLAIAAVIWLASTLISCPMMIIYR 239
            .|...|..:::..|||||.||.:|||.|.:.||:.|:|......:.:.||:.|..:..|.:....
Zfish   133 YLVFLIQPVTVYVSVFTLTAIGVDRYYATVHPLKKRISVLACTYLLSGIWILSCGLVAPAVAHTY 197

  Fly   240 TEEVPVRGLSNRTVCYPEWPDGPTNHSTMESLYNILIIILTYFLPIVSMTVTYSRVGIELWGSKT 304
            ..|....|.   |:|...|    .........|....:.:||.||:.::.::|..:.::|.....
Zfish   198 HVEFKDEGF---TICEEFW----MGQEKERLAYAYSTLFITYVLPLSALCISYLCISVKLRNCVV 255

  Fly   305 IGECTPRQVENVRS-KRRVVKMMIVVVLIFAICWLPFHSYFIITSCYPAITEAPFIQELYLAIYW 368
            .|..|..|.|..|: ||:..:::.:||..|.|||||...:.::......:.:..:...:.|..:.
Zfish   256 PGHRTQSQAEAQRARKRKTFRLVSLVVAAFGICWLPISVFNVLRDIDIDLIDKRYFLLIQLLCHL 320

  Fly   369 LAMSNSMYNPIIYCWMNSRFRYGFKMVF 396
            ..||:|..||.:|.|::.|||...:.:|
Zfish   321 CGMSSSCCNPFLYAWLHDRFRAELRKMF 348

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TkR99D	NP_001263092.1	7tmA_TACR	102..392	CDD:320512	82/282 (29%)
		TM helix 1	103..129	CDD:320512	4/17 (24%)
		TM helix 2	136..162	CDD:320512	9/25 (36%)
		TM helix 3	174..204	CDD:320512	14/29 (48%)
		TM helix 4	215..236	CDD:320512	4/20 (20%)
		TM helix 5	269..298	CDD:320512	6/28 (21%)
		TM helix 6	317..347	CDD:320512	11/30 (37%)
		TM helix 7	360..385	CDD:320512	8/24 (33%)
prlhr2a	NP_001034615.1	7tmA_PrRP_R	59..344	CDD:320516	82/282 (29%)
		TM helix 1	60..86	CDD:320516	4/17 (24%)
		TM helix 2	93..118	CDD:320516	9/24 (38%)
		TM helix 3	132..162	CDD:320516	14/29 (48%)
		TM helix 4	173..194	CDD:320516	4/20 (20%)
		TM helix 5	220..249	CDD:320516	6/28 (21%)
		TM helix 6	269..299	CDD:320516	10/29 (34%)
		TM helix 7	312..337	CDD:320516	8/24 (33%)