Protein Alignment TkR99D and Npffr1

DIOPT Version :10

• Sequence 1: NP_001263092.1
• Gene: TkR99D / 43551
• FlyBaseID: FBgn0004622
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: XP_006256547.1
• Gene: Npffr1 / 64107
• RGDID: 621570
• Length: 468
• Species: Rattus norvegicus
• Alignment Length: 397
• Identity: 119/397 - (29%)
• Similarity: 177/397 - (44%)
• Gaps: 66/397 - (16%)

  Fly   118 GNLIVVWIVMTTKRMRTVTNYFIVNLSIADAMVSSLNVTFNYYYMLDSDWPFGEFYCKLSQFIAM 182
            ||.:|.:||:..:.||||||.||:||:::|.:|....:.......|.:.|||....||:|..:..
  Rat    96 GNTLVCFIVLKNRHMRTVTNMFILNLAVSDLLVGIFCMPTTLVDNLITGWPFDNATCKMSGLVQG 160

  Fly   183 LSICASVFTLMAISIDRYVAIIRPLQPRMSKRCNLAIAAVIWLASTLISCPMMI---IYRTEEVP 244
            :|:.||||||:||:::|:..|:.|.:.:::.|..|...||||..:.||.||..:   :.|.|...
  Rat   161 MSVSASVFTLVAIAVERFRCIVHPFREKLTLRKALFTIAVIWALALLIMCPSAVTLTVTREEHHF 225

  Fly   245 VRGLSNRTV----CYPEWPDGPTNHSTMESLYNILIIILTYFLPIVSMTVTYSRVGIELWGSKTI 305
            :....||:.    |:..||:     ..|..:|..::....|.:|:..:.|.|.|:..:|..:...
  Rat   226 MLDARNRSYPLYSCWEAWPE-----KGMRKVYTAVLFAHIYLVPLALIVVMYVRIARKLCQAPGP 285

  Fly   306 GECTPRQV-ENVRSKR---RVVKMMIVVVLIFAICWLPFHSYFIITSCYPAITEAPFIQELYLAI 366
            ...|...| |..|:.|   |||.|:::|.|.|.:.|||.....::.. |..::|   :|...|::
  Rat   286 ARDTEEAVAEGGRTSRRRARVVHMLVMVALFFTLSWLPLWVLLLLID-YGELSE---LQLHLLSV 346

  Fly   367 Y------WLAMSNSMYNPIIYCWMNSRFRYGFKMVFR-------WCLFVRVGTEPFSRRENLTSR 418
            |      |||..:|..|||||.:.|..||.||:..||       |.    ...:.:|.|.|...|
  Rat   347 YAFPLAHWLAFFHSSANPIIYGYFNENFRRGFQAAFRAQLCWPPWA----AHKQAYSERPNRLLR 407

  Fly   419 Y--------SCSGSPDHNRIKRNDTQKSILYTCPSSPKSHRISHSGTGRSATLRNSLPAESLSSG 475
            .        |.||.|..                 |.|.|   ...|.|| ..|||...|.....|
  Rat   408 RRVVVDVQPSDSGLPSE-----------------SGPSS---GVPGPGR-LPLRNGRVAHQDGPG 451

  Fly   476 GSGGGGH 482
            ...|..|
  Rat   452 EGPGCNH 458

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TkR99D	NP_001263092.1	7tmA_TACR	102..392	CDD:320512	93/290 (32%)
		TM helix 1	103..129	CDD:320512	5/10 (50%)
		TM helix 2	136..162	CDD:320512	8/25 (32%)
		TM helix 3	174..204	CDD:320512	13/29 (45%)
		TM helix 4	215..236	CDD:320512	9/20 (45%)
		TM helix 5	269..298	CDD:320512	6/28 (21%)
		TM helix 6	317..347	CDD:320512	12/32 (38%)
		TM helix 7	360..385	CDD:320512	12/30 (40%)
Npffr1	XP_006256547.1	7tmA_NPFFR1	80..378	CDD:320647	93/290 (32%)
		TM helix 1	81..107	CDD:320647	5/10 (50%)
		TM helix 2	114..140	CDD:320647	8/25 (32%)
		TM helix 3	152..182	CDD:320647	13/29 (45%)
		TM helix 4	193..214	CDD:320647	9/20 (45%)
		TM helix 5	249..278	CDD:320647	6/28 (21%)
		TM helix 6	301..331	CDD:320647	11/29 (38%)
		TM helix 7	346..371	CDD:320647	10/24 (42%)