DRSC/TRiP Functional Genomics Resources

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Protein Alignment TkR99D and kiss1ra

DIOPT Version :10

Sequence 1:NP_001263092.1 Gene:TkR99D / 43551 FlyBaseID:FBgn0004622 Length:564 Species:Drosophila melanogaster
Sequence 2:NP_001099149.2 Gene:kiss1ra / 561898 ZFINID:ZDB-GENE-070912-521 Length:366 Species:Danio rerio


Alignment Length:364 Identity:98/364 - (26%)
Similarity:172/364 - (47%) Gaps:58/364 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly    56 STSSFNHSQTLSTDLPAVGDVEDAA-EDAAASMETGSFAFVVPWWRQVLWSILFGGMVIVATGGN 119
            |...:|.|:.|:      |...::: ||:    |.|...|:...|   |..:.|..:::|...||
Zfish     3 SGEDWNSSELLN------GSFRNSSMEDS----EDGEHPFLTDAW---LVPLFFSLIMLVGLIGN 54

  Fly   120 LIVVWIVMTTKRMRTVTNYFIVNLSIADAMVSSLNVTFNYYYMLDSDWPFGEFYCKLSQFIAMLS 184
            .:|::::...::|||.||::|.||:..|.:.....|.|.........|.||:|.||...|:..::
Zfish    55 SLVIYVISKHRQMRTATNFYIANLAATDIIFLLCCVPFTATLYPLPGWIFGDFMCKFVAFLQQVT 119

  Fly   185 ICASVFTLMAISIDRYVAIIRPLQ------PRMSKRCNLAIAAVIWLASTLISCPMMIIYRTEEV 243
            :.|:..||.|:|.||....:.||:      ||::    :.::..||:.|.::|.|:.:..|.|:.
Zfish   120 VQATCITLTAMSGDRCYVTVYPLKSLHHRTPRVA----MIVSICIWIGSFILSIPIFLYQRLEDG 180

  Fly   244 PVRGLSNRTVCYPEWPDGPTNHSTMESLYNILIIILTYFLPIVSMTVTYSRVGIELWGSKTIGEC 308
            ...|  .|..|...:|.     .|.|..:.:...|..|.||:::::..||      :..|.:|:.
Zfish   181 YWYG--PRKYCMERFPS-----KTHEKAFILYQFIAVYLLPVITISFCYS------FMLKRVGQA 232

  Fly   309 TPRQVEN-------------VRSKRRVVKMMIVVVLIFAICWLPFHSYFIITSCYPAITEAPFIQ 360
            :...|:|             :|||  :.||::|:|::|.|||.|...:.:..|.||.. :|.:  
Zfish   233 SVEPVDNNHQVHLLSERTISIRSK--ISKMVVVIVVLFTICWGPIQIFVLFQSFYPNF-KANY-- 292

  Fly   361 ELYLAIYW---LAMSNSMYNPIIYCWMNSRFRYGFKMVF 396
            ..|....|   ::.:||..|||:|.:|.:.||..|:..|
Zfish   293 ATYKIKTWANCMSYANSSINPIVYGFMGASFRKSFRKTF 331

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
TkR99DNP_001263092.1 7tmA_TACR 102..392 CDD:320512 85/311 (27%)
TM helix 1 103..129 CDD:320512 6/25 (24%)
TM helix 2 136..162 CDD:320512 8/25 (32%)
TM helix 3 174..204 CDD:320512 10/29 (34%)
TM helix 4 215..236 CDD:320512 5/20 (25%)
TM helix 5 269..298 CDD:320512 7/28 (25%)
TM helix 6 317..347 CDD:320512 12/29 (41%)
TM helix 7 360..385 CDD:320512 8/27 (30%)
kiss1raNP_001099149.2 7tmA_KiSS1R 37..327 CDD:320223 86/314 (27%)
TM helix 1 38..64 CDD:320223 6/25 (24%)
TM helix 2 71..97 CDD:320223 8/25 (32%)
TM helix 3 109..139 CDD:320223 10/29 (34%)
TM helix 4 151..171 CDD:320223 5/23 (22%)
TM helix 5 199..228 CDD:320223 7/34 (21%)
TM helix 6 252..282 CDD:320223 12/31 (39%)
TM helix 7 295..320 CDD:320223 8/24 (33%)

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