Protein Alignment TkR99D and npffr2a

DIOPT Version :10

• Sequence 1: NP_001263092.1
• Gene: TkR99D / 43551
• FlyBaseID: FBgn0004622
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_001098579.1
• Gene: npffr2a / 560955
• ZFINID: ZDB-GENE-060526-183
• Length: 422
• Species: Danio rerio
• Alignment Length: 410
• Identity: 118/410 - (28%)
• Similarity: 198/410 - (48%)
• Gaps: 60/410 - (14%)

  Fly    81 EDAAASMETGSFAFVVPWWRQVLWSILFGG------------------MVIVATGGNLIVVWIVM 127
            :|...:...||..|.:|     |.:|.:.|                  :.:|...||.:|.:||:
Zfish    13 DDGNWTFINGSSEFFLP-----LNNITYVGYYLHQPSVAAVFIVSYLLIFLVCMIGNGVVCFIVL 72

  Fly   128 TTKRMRTVTNYFIVNLSIADAMVSSLNVTFNYYYMLDSDWPFGEFYCKLSQFIAMLSICASVFTL 192
            .:|.||||||.||:||:|:|.:|....:.......:.:.||||...||:|..:..:|:.||||||
Zfish    73 RSKNMRTVTNLFILNLAISDLLVGIFCMPTTLLDNIITGWPFGSMVCKMSGMVQGISVSASVFTL 137

  Fly   193 MAISIDRYVAIIRPLQPRMSKRCNLAIAAVIWLASTLISCP---MMIIYRTEEVPVRGLSNRTV- 253
            :||::||:..|:.|.:.:::......|..:||:.:..|.||   |:.:.:.:.:.|...:||:.
Zfish   138 VAIAVDRFRCIVYPFKQKLTISTATFIIVIIWVLAVSIMCPSGVMLQVTKEQNIRVFRGNNRSSP 202

  Fly   254 ---CYPEWPDGPTNHSTMESLYNILIIILTYFLPIVSMTVTYSRVGIELW------GSKTIGECT 309
               |...||     :..|..:|..::....|..|:..:.:.|:|:||.|:      |.|. |...
Zfish   203 FYWCRENWP-----NQEMRKIYTTVLFANIYLAPLSLIVIMYARIGITLFKTAMPAGGKH-GHDN 261

  Fly   310 PRQVENVRSKRRVVKMMIVVVLIFAICWLPFHSYFIITSCYPAITEAPF-IQELYL--AIYWLAM 371
            ...|.  :.|:||:||:::|.|:|.:.|||..:..::|. |..:||..: :..:|:  ..:|||.
Zfish   262 RHSVS--KKKQRVIKMLLIVALLFILSWLPLWTLMMLTD-YVKLTEHQYRVINIYIYPFAHWLAF 323

  Fly   372 SNSMYNPIIYCWMNSRFRYGFKMVFRWCLFVRVGTE--PFSRRENLTSRYSCSGSPDHNRIKRND 434
            .||..|||||.:.|..||.||:.:|::.| ..||.:  .:|.|....|....:..|....|..|.
Zfish   324 FNSSVNPIIYGFFNENFRRGFQAIFKFGL-CPVGGQHRTYSHRVQGNSVQPVNLQPSTEPISLNS 387

  Fly   435 TQKSILYTCPSSPKSHRISH 454
            .:.:         .|.|::|
Zfish   388 LENN---------SSRRMNH 398

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TkR99D	NP_001263092.1	7tmA_TACR	102..392	CDD:320512	98/323 (30%)
		TM helix 1	103..129	CDD:320512	9/43 (21%)
		TM helix 2	136..162	CDD:320512	9/25 (36%)
		TM helix 3	174..204	CDD:320512	14/29 (48%)
		TM helix 4	215..236	CDD:320512	7/23 (30%)
		TM helix 5	269..298	CDD:320512	6/28 (21%)
		TM helix 6	317..347	CDD:320512	11/29 (38%)
		TM helix 7	360..385	CDD:320512	11/26 (42%)
npffr2a	NP_001098579.1	7tmA_NPFFR2	47..344	CDD:320646	95/305 (31%)
		TM helix 1	48..74	CDD:320646	6/25 (24%)
		TM helix 2	81..107	CDD:320646	9/25 (36%)
		TM helix 3	119..149	CDD:320646	14/29 (48%)
		TM helix 4	160..181	CDD:320646	6/20 (30%)
		TM helix 5	216..245	CDD:320646	6/28 (21%)
		TM helix 6	267..297	CDD:320646	11/29 (38%)
		TM helix 7	312..337	CDD:320646	11/24 (46%)