Protein Alignment TkR99D and AstA-R1

DIOPT Version :10

• Sequence 1: NP_001263092.1
• Gene: TkR99D / 43551
• FlyBaseID: FBgn0004622
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_524700.1
• Gene: AstA-R1 / 44126
• FlyBaseID: FBgn0266429
• Length: 394
• Species: Drosophila melanogaster
• Alignment Length: 404
• Identity: 109/404 - (26%)
• Similarity: 193/404 - (47%)
• Gaps: 64/404 - (15%)

  Fly    18 SNW--SNWSTPAGVLFSAMSSVLSASNHTPLPDFGQELALSTSSFNHSQTLSTDLPAVGDVEDAA 80
            |:|  ::|..      :...|::|.||.:     |...|.::...:||...:.|     .:|..|
  Fly    16 SSWPKASWGA------TGNGSIISVSNSS-----GNNYAFTSEHTDHSDHNAND-----SMEYDA 64

  Fly    81 EDAAASMETGSFAFVVPWWRQVLWSIL-FGGMVIVATGGNLIVVWIVMTTKRMRTVTNYFIVNLS 144
            |..|......:   :||    |.:.|: |.|::     ||.:|:.:|:..::||:.||..|:||:
  Fly    65 ESVALERIVST---IVP----VFFGIIGFAGLL-----GNGLVILVVVANQQMRSTTNLLIINLA 117

  Fly   145 IADAMVSSLNVTFNYYYMLDSDWPFGEFYCKLSQFIAMLSICASVFTLMAISIDRYVAIIRP--- 206
            ::|.:.....|.|.....:..:||||..:||..|::.:::...||:||:.:|.||::|::.|
  Fly   118 VSDILFVIFCVPFTATDYVLPEWPFGNVWCKFVQYMIVVTCHCSVYTLVLMSFDRFLAVVHPVTS 182

  Fly   207 LQPRMSKRCNLAIAAVIWLASTLISCPMMIIYRTEEVPVRGLSNRTVCYPEWPDGPTNHSTMESL 271
            :..|..:...|||... |:.....:.|:.:.:........|.:. |.|.         .||.|.:
  Fly   183 MSLRTERNATLAIMCA-WITIVTTAIPVALSHSVRIYQYHGNAG-TACV---------FSTEEEI 236

  Fly   272 YNILIIILTYFL-----PIVSMTVTYSRVGIELWGSKTIGECTPRQVENVRSKRRVVKMMIVVVL 331
            ::::...:::||     |:..:...|..:...||  |:...|.| ..|:.:.||||.:|::||||
  Fly   237 WSLVGFQVSFFLSSYVAPLTLICFLYMGMLARLW--KSAPGCKP-SAESRKGKRRVTRMVVVVVL 298

  Fly   332 IFAICWLPFHSYFII--TSCYPAITEAPFIQELYLAIYWLAMSNSMYNPIIYCWMNSRFRYGFKM 394
            .|||||||.|...::  .:.|.....:..||   :..:.:|.:||..|||:|.:::..||..|:.
  Fly   299 AFAICWLPIHVILVLKALNLYGGSHLSVIIQ---IISHVVAYTNSCINPILYAFLSDNFRKAFRK 360

  Fly   395 VFRWCLFVRVGTEP 408
            |. ||     |:.|
  Fly   361 VV-WC-----GSPP 368

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TkR99D	NP_001263092.1	7tmA_TACR	102..392	CDD:320512	85/300 (28%)
		TM helix 1	103..129	CDD:320512	7/26 (27%)
		TM helix 2	136..162	CDD:320512	8/25 (32%)
		TM helix 3	174..204	CDD:320512	11/29 (38%)
		TM helix 4	215..236	CDD:320512	5/20 (25%)
		TM helix 5	269..298	CDD:320512	5/33 (15%)
		TM helix 6	317..347	CDD:320512	17/31 (55%)
		TM helix 7	360..385	CDD:320512	8/24 (33%)
AstA-R1	NP_524700.1	7tmA_AstA_R_insect	75..358	CDD:320224	87/311 (28%)
		TM helix 1	76..102	CDD:320224	10/34 (29%)
		TM helix 2	109..135	CDD:320224	8/25 (32%)
		TM helix 3	147..177	CDD:320224	11/29 (38%)
		TM helix 4	189..209	CDD:320224	4/20 (20%)
		TM helix 5	239..268	CDD:320224	4/28 (14%)
		TM helix 6	284..314	CDD:320224	17/29 (59%)
		TM helix 7	326..351	CDD:320224	9/27 (33%)