Protein Alignment TkR99D and AstA-R2

DIOPT Version :10

• Sequence 1: NP_001263092.1
• Gene: TkR99D / 43551
• FlyBaseID: FBgn0004622
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_524544.1
• Gene: AstA-R2 / 43393
• FlyBaseID: FBgn0039595
• Length: 357
• Species: Drosophila melanogaster
• Alignment Length: 346
• Identity: 98/346 - (28%)
• Similarity: 173/346 - (50%)
• Gaps: 51/346 - (14%)

  Fly    96 VPWWRQVLWSILFGGMVIVATGGNLIVVWIVMTTKRMRTVTNYFIVNLSIADAMVSSLNVTFN-- 158
            :||    :....||.:.|....|||:|:.:|:....||:.||..||||:.||.|...|.:.|.
  Fly    37 LPW----IVGFFFGVIAITGFFGNLLVILVVVFNNNMRSTTNLMIVNLAAADLMFVILCIPFTAT 97

  Fly   159 ---YYYMLDSDWPFGEFYCKLSQFIAMLSICASVFTLMAISIDRYVAIIRPLQPRMSKRCNLAIA 220
               .||     ||:|.|:|:..|::.:::..||::||:.:||||::|::.|::.||.:..|:.:.
  Fly    98 DYMVYY-----WPYGRFWCRSVQYLIVVTAFASIYTLVLMSIDRFLAVVHPIRSRMMRTENITLI 157

  Fly   221 AVI--WLASTLISCPMMIIYRTEEVPVRGLSNRTVCYPEWPDGPTNHSTMESL----YNILIIIL 279
            |::  |:...::|.|:..   |.:|.|...:.:.:.|     |....:|.:.|    |.:...|.
  Fly   158 AIVTLWIVVLVVSVPVAF---THDVVVDYDAKKNITY-----GMCTFTTNDFLGPRTYQVTFFIS 214

  Fly   280 TYFLPIVSMTVTYSRVGIELWGSKTIGECTPRQVENVRSKRRVVKMMIVVVLIFAICWLPFHSYF 344
            :|.||::.::..|.|:.:.||..   |.......|:.|.::||.::::|||:.||..|||.....
  Fly   215 SYLLPLMIISGLYMRMIMRLWRQ---GTGVRMSKESQRGRKRVTRLVVVVVIAFASLWLPVQLIL 276

  Fly   345 IITSCYPAITEAPFIQELYLAI--YWLAMSNSMYNPIIYCWMNSRFRYGFKMVFRWCLFVRVGTE 407
            ::.|.  .:.|...:.:|.:.:  ..||.|:|..||::|.:::..||..|..... |
  Fly   277 LLKSL--DVIETNTLTKLVIQVTAQTLAYSSSCINPLLYAFLSENFRKAFYKAVN-C-------- 330

  Fly   408 PFSRRENLTS------RYSCS 422
             .||.:|.||      :.||:
  Fly   331 -SSRYQNYTSDLPPPRKTSCA 350

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TkR99D	NP_001263092.1	7tmA_TACR	102..392	CDD:320512	87/302 (29%)
		TM helix 1	103..129	CDD:320512	8/25 (32%)
		TM helix 2	136..162	CDD:320512	12/30 (40%)
		TM helix 3	174..204	CDD:320512	11/29 (38%)
		TM helix 4	215..236	CDD:320512	5/22 (23%)
		TM helix 5	269..298	CDD:320512	8/32 (25%)
		TM helix 6	317..347	CDD:320512	11/29 (38%)
		TM helix 7	360..385	CDD:320512	8/26 (31%)
AstA-R2	NP_524544.1	7tmA_AstA_R_insect	39..324	CDD:320224	88/306 (29%)
		TM helix 1	40..66	CDD:320224	8/25 (32%)
		TM helix 2	73..99	CDD:320224	11/25 (44%)
		TM helix 3	111..141	CDD:320224	11/29 (38%)
		TM helix 4	153..173	CDD:320224	4/19 (21%)
		TM helix 5	204..233	CDD:320224	7/28 (25%)
		TM helix 6	249..279	CDD:320224	11/29 (38%)
		TM helix 7	292..317	CDD:320224	8/24 (33%)