Protein Alignment TkR99D and RYa-R

DIOPT Version :10

• Sequence 1: NP_001263092.1
• Gene: TkR99D / 43551
• FlyBaseID: FBgn0004622
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_001287552.1
• Gene: RYa-R / 43253
• FlyBaseID: FBgn0004842
• Length: 518
• Species: Drosophila melanogaster
• Alignment Length: 496
• Identity: 145/496 - (29%)
• Similarity: 239/496 - (48%)
• Gaps: 72/496 - (14%)

  Fly    26 PAGVLFSAMSSVLSASNHTPLPDFGQELALSTSSF-NHSQTLSTDLPAVGDVEDAAEDAAASMET 89
            ||.::::  ::.|.|.:......:|....||...| .::.|:..:. :..|.:..:||..:|.
  Fly    43 PASLIYN--TTALPADDEGSNYGYGSTTTLSGLQFETYNITVMMNF-SCDDYDLLSEDMWSSA-- 102

  Fly    90 GSFAFVVPWWRQVLWSILFGGMVIVATGGNLIVVWIVMTTKRMRTVTNYFIVNLSIADAMVSSLN 154
                     :.:::..:|:..:.|.|..||..|.:||.:|.||||||||||.:|:|.|.::|...
  Fly   103 ---------YFKIIVYMLYIPIFIFALIGNGTVCYIVYSTPRMRTVTNYFIASLAIGDILMSFFC 158

  Fly   155 V--TFNYYYMLDSDWPFGEFYCKLSQFIAMLSICASVFTLMAISIDRYVAIIRPLQPRMSKRCNL 217
            |  :|...::|:. ||||...|....:...:|:..|.:||:|||||||:||:.||:||::||...
  Fly   159 VPSSFISLFILNY-WPFGLALCHFVNYSQAVSVLVSAYTLVAISIDRYIAIMWPLKPRITKRYAT 222

  Fly   218 AIAAVIWLASTLISCPMMIIYRTEEVPV---RGLSNRTVCYPEWPDGPTNHSTMESLYNILIIIL 279
            .|.|.:|..:...:.|:.|:... ::|:   .....:.:|...||.     .|.|..|.:.:..|
  Fly   223 FIIAGVWFIALATALPIPIVSGL-DIPMSPWHTKCEKYICREMWPS-----RTQEYYYTLSLFAL 281

  Fly   280 TYFLPIVSMTVTYSRVGIELWGSKTIGEC-TPRQVENVRSKRRVVKMMIVVVLIFAICWLPFHSY 343
            .:.:|:..:..||:|:.|.:|..:..||. |.|.....||||::||||:.||::|..|||||:..
  Fly   282 QFVVPLGVLIFTYARITIRVWAKRPPGEAETNRDQRMARSKRKMVKMMLTVVIVFTCCWLPFNIL 346

  Fly   344 FIITSCYPAITEAPF-----IQELYLAIYWLAMSNSMYNPIIYCWMNSRFRYGFKMVF------- 396
            .::      :.:..|     :..::.|.:|||||:..|||||||:||:|||.||..:.
  Fly   347 QLL------LNDEEFAHWDPLPYVWFAFHWLAMSHCCYNPIIYCYMNARFRSGFVQLMHRMPGLR 405

  Fly   397 RWCLFVRVGTEPFSRRENLTSRY-----------------------SCSGSPDHNRIKRNDTQKS 438
            |||....||....:....:|::|                       |.|....|:..:|:....|
  Fly   406 RWCCLRSVGDRMNATSGEMTTKYHRHVGDALFRKPKICIRNGSSTSSQSNEHIHHLHQRSSKATS 470

  Fly   439 ILYTCPSSPKSHRISHSGTGRSATLRNSLPAESLSSGGSGG 479
            .::.  |.|...|...: |..:...:|...:....||.|||
  Fly   471 DIFA--SEPIIVRRDVT-TAVAVISKNKTDSPVRRSGSSGG 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TkR99D	NP_001263092.1	7tmA_TACR	102..392	CDD:320512	108/300 (36%)
		TM helix 1	103..129	CDD:320512	8/25 (32%)
		TM helix 2	136..162	CDD:320512	11/27 (41%)
		TM helix 3	174..204	CDD:320512	13/29 (45%)
		TM helix 4	215..236	CDD:320512	4/20 (20%)
		TM helix 5	269..298	CDD:320512	7/28 (25%)
		TM helix 6	317..347	CDD:320512	16/29 (55%)
		TM helix 7	360..385	CDD:320512	13/24 (54%)
RYa-R	NP_001287552.1	7tmA_PR4-like	106..394	CDD:320514	108/300 (36%)
		TM helix 1	107..133	CDD:320514	8/25 (32%)
		TM helix 2	140..165	CDD:320514	11/24 (46%)
		TM helix 3	179..209	CDD:320514	13/29 (45%)
		TM helix 4	220..241	CDD:320514	4/20 (20%)
		TM helix 5	271..300	CDD:320514	7/28 (25%)
		TM helix 6	320..350	CDD:320514	16/35 (46%)
		TM helix 7	362..387	CDD:320514	13/24 (54%)