Protein Alignment TkR99D and TkR86C

DIOPT Version :10

• Sequence 1: NP_001263092.1
• Gene: TkR99D / 43551
• FlyBaseID: FBgn0004622
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_001097741.1
• Gene: TkR86C / 41286
• FlyBaseID: FBgn0004841
• Length: 555
• Species: Drosophila melanogaster
• Alignment Length: 494
• Identity: 180/494 - (36%)
• Similarity: 264/494 - (53%)
• Gaps: 85/494 - (17%)

  Fly    59 SFNHSQTLS---------TDLPAVGDVEDAAEDAAASMETGSFAFVVPWWRQVLWSILFGGMVIV 114
            |.|.::.:|         .:|.::.:.:|...:......|..:.  :||.::.:|:|:||.|:.|
  Fly    34 SLNRTEVVSLLSSIIDNRDNLESINEAKDFLTECLFPSPTRPYE--LPWEQKTIWAIIFGLMMFV 96

  Fly   115 ATGGNLIVVWIVMTTKRMRTVTNYFIVNLSIADAMVSSLNVTFNYYYMLDSDWPFGEFYCKLSQF 179
            |..||.||:|||...:.||||||||::||||||.::||||..||:.:||:||||||..||.::.|
  Fly    97 AIAGNGIVLWIVTGHRSMRTVTNYFLLNLSIADLLMSSLNCVFNFIFMLNSDWPFGSIYCTINNF 161

  Fly   180 IAMLSICASVFTLMAISIDRYVAIIRPLQPRMSKRCNLAIAAVIWLASTLISCPMMIIYRTEEVP 244
            :|.:::..|||||:|||.|||:||:.||:.|.|:|....|..:||..|.::|.|.::........
  Fly   162 VANVTVSTSVFTLVAISFDRYIAIVHPLKRRTSRRKVRIILVLIWALSCVLSAPCLLYSSIMTKH 226

  Fly   245 VRGLSNRTVCYPEWPDGPTNHSTMESLYNILIIILTYFLPIVSMTVTYSRVGIELWGSKTIGECT 309
            .....:||||:..||||....|..:..||::|::|||.:|::.|.:.||.:|..||||::|||.|
  Fly   227 YYNGKSRTVCFMMWPDGRYPTSMADYAYNLIILVLTYGIPMIVMLICYSLMGRVLWGSRSIGENT 291

  Fly   310 PRQVENVRSKRRVVKMMIVVVLIFAICWLPFHSYFIITSCYPAITEAPFIQELYLAIYWLAMSNS 374
            .||:|:::|||:||:|.|.:|.||||||||:|.:||.......:....::|.:||..|||||||:
  Fly   292 DRQMESMKSKRKVVRMFIAIVSIFAICWLPYHLFFIYAYHNNQVASTKYVQHMYLGFYWLAMSNA 356

  Fly   375 MYNPIIYCWMNSRFRYGFKMVFRWCLFVRVGTEPFSRRENLTSRYSCSGSPDHNRIKRNDTQKSI 439
            |.||:||.|||.|||..|:.:...|                     |.|...|    |.|:.||.
  Fly   357 MVNPLIYYWMNKRFRMYFQRIICCC---------------------CVGLTRH----RFDSPKSR 396

  Fly   440 LYTCPSSPKSHRISHSGTGRSATLRNSLPAESLSSGGSGGGGHRKRLSYQQEMQQRWSGPNSATA 504
            | |..:|...|      |....|:.:|||
  Fly   397 L-TNKNSSNRH------TRGGYTVAHSLP------------------------------------ 418

  Fly   505 VTNSSSTANTTQLLSXQPAIQVVPPEMQTQIVCS--SPY 541
                :|:..|||.|. ..|..:..|:.|||::.|  ||:
  Fly   419 ----NSSPPTTQTLLAVLAQTLTQPKPQTQLLLSHHSPH 453

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TkR99D	NP_001263092.1	7tmA_TACR	102..392	CDD:320512	141/289 (49%)
		TM helix 1	103..129	CDD:320512	14/25 (56%)
		TM helix 2	136..162	CDD:320512	16/25 (64%)
		TM helix 3	174..204	CDD:320512	15/29 (52%)
		TM helix 4	215..236	CDD:320512	6/20 (30%)
		TM helix 5	269..298	CDD:320512	11/28 (39%)
		TM helix 6	317..347	CDD:320512	19/29 (66%)
		TM helix 7	360..385	CDD:320512	16/24 (67%)
TkR86C	NP_001097741.1	7tmA_TACR	84..374	CDD:320512	141/289 (49%)
		TM helix 1	85..111	CDD:320512	14/25 (56%)
		TM helix 2	118..144	CDD:320512	16/25 (64%)
		TM helix 3	156..186	CDD:320512	15/29 (52%)
		TM helix 4	197..218	CDD:320512	6/20 (30%)
		TM helix 5	251..280	CDD:320512	11/28 (39%)
		TM helix 6	299..329	CDD:320512	19/29 (66%)
		TM helix 7	342..367	CDD:320512	16/24 (67%)