Protein Alignment TkR99D and sNPF-R

DIOPT Version :10

• Sequence 1: NP_001263092.1
• Gene: TkR99D / 43551
• FlyBaseID: FBgn0004622
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_524176.1
• Gene: sNPF-R / 40195
• FlyBaseID: FBgn0036934
• Length: 600
• Species: Drosophila melanogaster
• Alignment Length: 510
• Identity: 126/510 - (24%)
• Similarity: 195/510 - (38%)
• Gaps: 126/510 - (24%)

  Fly    32 SAMSSVLSASNHTPLPDFGQELALSTSSFNHSQTLSTDLPAVGDVEDAAEDAAASMETGSFAFVV 96
            |.:|::.:.|:           ::|||......|.:..|.:.|.......|.|||.|..|...:.
  Fly     5 SWLSTITTTSS-----------SISTSQLPLVSTTNWSLTSPGTTSAILADVAASDEDRSGGIIH 58

  Fly    97 PWWRQVLWSILFGGMVIVATGGNLIVVWIVMTTKRMRTVTNYFIVNLSIADAMVSSLNVTFNYYY 161
            ..:.|:.:.:|:..:.::...||::|.::|:..:.|:||||.||.||:::|.::..|.|.|...|
  Fly    59 NQFVQIFFYVLYATVFVLGVFGNVLVCYVVLRNRAMQTVTNIFITNLALSDILLCVLAVPFTPLY 123

  Fly   162 MLDSDWPFGEFYCKLSQFIAMLSICASVFTLMAISIDRYVAIIRPLQPRMSKRCNLAIAAVIWLA 226
            .....|.||...|.|..|....||..|..||.:|:||||..||.|..|||.....:.|...||:.
  Fly   124 TFMGRWAFGRSLCHLVSFAQGCSIYISTLTLTSIAIDRYFVIIYPFHPRMKLSTCIGIIVSIWVI 188

  Fly   227 STLISCPM-MIIYRTEEVPVRGLSN---------------------------------------- 250
            :.|.:.|. |.:..|.|: |.|...
  Fly   189 ALLATVPYGMYMKMTNEL-VNGTQTGNETLVEATLMLNGSFVAQGSGFIEAPDSTSATQAYMQVM 252

  Fly   251 ------------RTVCYPEWPDGPTNHSTMESLYNILIIILTYFLPIVSMTVTYSRVGIEL---- 299
                        |..|...||.     .....::..:...|.:.||...:::.|..:.::|
  Fly   253 TAGSTGPEMPYVRVYCEENWPS-----EQYRKVFGAITTTLQFVLPFFIISICYVWISVKLNQRA 312

  Fly   300 ---WGSKTIGECTPRQVENVRSKRRVVKMMIVVVLIFAICWLPFHSYFIITSCYPAITEAPFIQE 361
               .|||:    :.|:..:...|:|..:|:|.:|.:|.:.|||.:...|.........|..|...
  Fly   313 RAKPGSKS----SRREEADRDRKKRTNRMLIAMVAVFGLSWLPINVVNIFDDFDDKSNEWRFYIL 373

  Fly   362 LYLAIYWLAMSNSMYNPIIYCWMNSRFRYGFKMVFRWCLFVRVGTEPFSRR-ENLTSRYSCSGSP 425
            .:...:.:|||::.|||.:|.|:|..||..||.|.. |.      .|.:.. .|:|..|
  Fly   374 FFFVAHSIAMSSTCYNPFLYAWLNENFRKEFKHVLP-CF------NPSNNNIINITRGY------ 425

  Fly   426 DHNRIKRNDTQKSILYTCPSSPKSHRISHSGTGRSATLRNSLPAESLSSGGSGGG 480
              ||..||        ||  .|:.|.    |.|               .||.|||
  Fly   426 --NRSDRN--------TC--GPRLHH----GKG---------------DGGMGGG 449

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TkR99D	NP_001263092.1	7tmA_TACR	102..392	CDD:320512	87/349 (25%)
		TM helix 1	103..129	CDD:320512	5/25 (20%)
		TM helix 2	136..162	CDD:320512	10/25 (40%)
		TM helix 3	174..204	CDD:320512	13/29 (45%)
		TM helix 4	215..236	CDD:320512	5/21 (24%)
		TM helix 5	269..298	CDD:320512	4/28 (14%)
		TM helix 6	317..347	CDD:320512	10/29 (34%)
		TM helix 7	360..385	CDD:320512	8/24 (33%)
sNPF-R	NP_524176.1	7tmA_NPYR-like	64..404	CDD:320331	87/349 (25%)
		TM helix 1	65..91	CDD:320331	5/25 (20%)
		TM helix 2	98..123	CDD:320331	10/24 (42%)
		TM helix 3	136..166	CDD:320331	13/29 (45%)
		TM helix 4	177..198	CDD:320331	5/20 (25%)
		TM helix 5	278..307	CDD:320331	4/28 (14%)
		TM helix 6	329..359	CDD:320331	10/29 (34%)
		TM helix 7	372..397	CDD:320331	8/24 (33%)