Protein Alignment TkR99D and CG4313

DIOPT Version :10

• Sequence 1: NP_001263092.1
• Gene: TkR99D / 43551
• FlyBaseID: FBgn0004622
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_569971.3
• Gene: CG4313 / 31169
• FlyBaseID: FBgn0025632
• Length: 541
• Species: Drosophila melanogaster
• Alignment Length: 492
• Identity: 98/492 - (19%)
• Similarity: 159/492 - (32%)
• Gaps: 192/492 - (39%)

  Fly   100 RQVLWS--------------ILFGGMVIVATGGNLIVVWIVMTTKRMRTVTNYFIVNLSIADAMV 150
            ||||:.              |:|   :||...|||:.:..:...::.|..|..||:|||.:|.:.
  Fly    65 RQVLFEGYSDELLTIAWVACIVF---IIVGVPGNLLTIVALSRGRQTRNSTAIFIINLSCSDLLF 126

  Fly   151 SSLNVTFNYYYMLDSDWPFGEFYCKLSQFIAMLSICASVFTLMAISIDRYVAIIRPLQ-PRMSKR 214
            ...|:........:..|...:..|:|...:....:..|:.::..|:|:||:.|..|.| ||:.:|
  Fly   127 GCFNLPLAASTFKERAWTHSDLLCRLFPMLRYGLLAVSLLSVSLITINRYIIIAHPRQYPRIYQR 191

  Fly   215 CNLAI-AAVIWLASTLI-------------------SCPMM------------------------ 235
            ..||: .|..|:.:..|                   ||.:|
  Fly   192 RYLALMVAGTWITTFSIMIPTWRGVWGIFGLDVSIGSCSIMHDRYGRSPKEFLFIAAFMVPCICI 256

  Fly   236 ------IIYRTEEVPVR-GLSNRT-----------------VCYPEWPDGPTNHS---------- 266
                  |.....:..:| |.:.:|                 :..|:.|:..|..|
  Fly   257 VICYARIFLLVRKAAIRAGTAGKTNVSDVTPSSAPQHQIQAMATPKKPEKVTTSSGEANEPIAGR 321

  Fly   267 ---TMESLYNILIIILTYFLPIV-------------------------------SMTVTYSRVGI 297
               ..|:|..|.....|..|||.                               ...|:..|...
  Fly   322 PFVVEENLAYIDDNASTDSLPISYSIRRRDQDQQPPPVDANVVLKEREKERDRDQEKVSLGRSQT 386

  Fly   298 ELWGSKTIGE--------------CTPRQ--------VENVRS---------KRRVVKMMIVVVL 331
            :|...||.|:              .:||:        ..|..|         .||::||::|:.:
  Fly   387 QLEMGKTHGKNPITTSLRTTSFTRFSPRKSHYASMGNTSNASSIYPGRMSAKDRRLLKMILVIFV 451

  Fly   332 IFAICWLPFHSYFIITSCYPAITEAPFIQELYLAIYWLAMSNSMYNPIIYCWMNSRFRYGFKMVF 396
            .|.||:||    ..:...:.:.||..:..   :|.|.|....:..||:||..|:|.:|..:
  Fly   452 WFVICYLP----ITVAKIWKSATEVHWFN---IAGYLLIYLTTCINPLIYVLMSSEYRRAY---- 505

  Fly   397 RWCLFVRVGTEPFSRRENLTSRYSCSGSPDHNRIKRN 433
             |.|.                  .|.||||..: :||
  Fly   506 -WNLL------------------RCHGSPDTQK-QRN 522

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TkR99D	NP_001263092.1	7tmA_TACR	102..392	CDD:320512	87/447 (19%)
		TM helix 1	103..129	CDD:320512	8/39 (21%)
		TM helix 2	136..162	CDD:320512	8/25 (32%)
		TM helix 3	174..204	CDD:320512	7/29 (24%)
		TM helix 4	215..236	CDD:320512	8/70 (11%)
		TM helix 5	269..298	CDD:320512	9/59 (15%)
		TM helix 6	317..347	CDD:320512	11/38 (29%)
		TM helix 7	360..385	CDD:320512	7/24 (29%)
CG4313	NP_569971.3	7tmA_GPR84-like	78..505	CDD:320338	85/436 (19%)
		TM helix 1	79..105	CDD:320338	7/28 (25%)
		TM helix 2	112..135	CDD:320338	8/22 (36%)
		TM helix 3	150..180	CDD:320338	7/29 (24%)
		TM helix 4	194..212	CDD:320338	5/17 (29%)
		TM helix 5	237..262	CDD:320338	0/24 (0%)
		TM helix 6	437..467	CDD:320338	10/33 (30%)
		TM helix 7	473..498	CDD:320338	7/27 (26%)