Protein Alignment TkR99D and Sstr4

DIOPT Version :10

• Sequence 1: NP_001263092.1
• Gene: TkR99D / 43551
• FlyBaseID: FBgn0004622
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_037168.1
• Gene: Sstr4 / 25555
• RGDID: 3764
• Length: 384
• Species: Rattus norvegicus
• Alignment Length: 347
• Identity: 95/347 - (27%)
• Similarity: 169/347 - (48%)
• Gaps: 59/347 - (17%)

  Fly    78 DAAEDAAASMETGSFAFVVPWWRQVLWSILFGGMVIVATGGNLIVVWIVMTTKRMRTVTNYFIVN 142
            |..|||..|..||:...|.   .|.::::    :.:|...||.:|:::::...:|:|.||.:::|
  Rat    27 DEEEDAVRSDGTGTAGMVT---IQCIYAL----VCLVGLVGNALVIFVILRYAKMKTATNIYLLN 84

  Fly   143 LSIADAMVSSLNVTFNYYYMLDSDWPFGEFYCKLSQFIAMLSICASVFTLMAISIDRYVAIIRPL 207
            |::||.:. .|:|.|.........||||...|:....:..|::..|||.|..:|:|||||::.||
  Rat    85 LAVADELF-MLSVPFVASAAALRHWPFGAVLCRAVLSVDGLNMFTSVFCLTVLSVDRYVAVVHPL 148

  Fly   208 ------QPRMSKRCNLAIAAVIWLASTLISCPMMIIYRTEEVPVRGLSNRTVCYPEWPDGPTNHS 266
                  :|.::|..||.    :||||.|::.|:.:...|.  |.|| .....|...||     |.
  Rat   149 RAATYRRPSVAKLINLG----VWLASLLVTLPIAVFADTR--PARG-GEAVACNLHWP-----HP 201

  Fly   267 TMESLYNILIIILTYFLPIVSMTVTYSRVGIELWGSKTIGECTPRQV-------ENVRSKRRVVK 324
            ...:::.|...:|.:.||::::.:.|..:         :|:.  |.|       :..||::::.:
  Rat   202 AWSAVFVIYTFLLGFLLPVLAIGLCYLLI---------VGKM--RAVALRAGWQQRRRSEKKITR 255

  Fly   325 MMIVVVLIFAICWLPFHSY----FIITSCYPAITEAPFIQELYLAIYWLAMSNSMYNPIIYCWMN 385
            ::::||.:|.:||:||:..    ..:||....:.....|         |:.:||..|||:|.:::
  Rat   256 LVLMVVTVFVLCWMPFYVVQLLNLFVTSLDATVNHVSLI---------LSYANSCANPILYGFLS 311

  Fly   386 SRFRYGFKMV--FRWCLFVRVG 405
            ..||..|:.|  .|.||....|
  Rat   312 DNFRRSFQRVLCLRCCLLETTG 333

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TkR99D	NP_001263092.1	7tmA_TACR	102..392	CDD:320512	80/306 (26%)
		TM helix 1	103..129	CDD:320512	4/25 (16%)
		TM helix 2	136..162	CDD:320512	9/25 (36%)
		TM helix 3	174..204	CDD:320512	12/29 (41%)
		TM helix 4	215..236	CDD:320512	8/20 (40%)
		TM helix 5	269..298	CDD:320512	5/28 (18%)
		TM helix 6	317..347	CDD:320512	9/33 (27%)
		TM helix 7	360..385	CDD:320512	7/24 (29%)
Sstr4	NP_037168.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..34		4/6 (67%)
		7tmA_SSTR4	44..318	CDD:320639	82/313 (26%)
		TM helix 1	45..71	CDD:320639	5/32 (16%)
		TM helix 2	78..104	CDD:320639	9/26 (35%)
		TM helix 3	115..145	CDD:320639	12/29 (41%)
		TM helix 4	157..179	CDD:320639	9/25 (36%)
		TM helix 5	204..233	CDD:320639	5/37 (14%)
		TM helix 6	248..278	CDD:320639	9/29 (31%)
		TM helix 7	286..311	CDD:320639	8/33 (24%)