Protein Alignment TkR99D and Sstr1

DIOPT Version :10

• Sequence 1: NP_001263092.1
• Gene: TkR99D / 43551
• FlyBaseID: FBgn0004622
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_036851.1
• Gene: Sstr1 / 25033
• RGDID: 3762
• Length: 391
• Species: Rattus norvegicus
• Alignment Length: 345
• Identity: 92/345 - (26%)
• Similarity: 167/345 - (48%)
• Gaps: 49/345 - (14%)

  Fly    71 PAVGDVEDAAEDAAASMETGSFAFVVPWWRQVLWSILFGGMVIVATGGNLIVVWIVMTTKRMRTV 135
            |..|..:...|....|.:.|:.:  ......:|.|.::..:.:|...||.:|:::::...:|:|.
  Rat    30 PGSGAADGMEEPGRNSSQNGTLS--EGQGSAILISFIYSVVCLVGLCGNSMVIYVILRYAKMKTA 92

  Fly   136 TNYFIVNLSIADAMVSSLNVTFNYYYMLDSDWPFGEFYCKLSQFIAMLSICASVFTLMAISIDRY 200
            ||.:|:||:|||.:: .|:|.|.....|...||||...|:|...:..:::..|::.|..:|:|||
  Rat    93 TNIYILNLAIADELL-MLSVPFLVTSTLLRHWPFGALLCRLVLSVDAVNMFTSIYCLTVLSVDRY 156

  Fly   201 VAIIRPL------QPRMSKRCNLAIAAVIWLASTLISCPMMIIYRTEEVPVRGLSNRTV-CYPEW 258
            ||::.|:      :|.::|..||.    :|:.|.|:..|:::..||     ...|:.|| |....
  Rat   157 VAVVHPIKAARYRRPTVAKVVNLG----VWVLSLLVILPIVVFSRT-----AANSDGTVACNMLM 212

  Fly   259 PDGPTNHSTMESLYNILI--------IILTYFLPIVSMTVTYSRVGIELWGSKTIGECTPRQVEN 315
            |:..........||..|:        |.|.|.|.|..|.:...:.|   |..:.
  Rat   213 PEPAQRWLVGFVLYTFLMGFLLPVGAICLCYVLIIAKMRMVALKAG---WQQRK----------- 263

  Fly   316 VRSKRRVVKMMIVVVLIFAICWLPFHSYFIITSCYPAITEAPFIQELYLAIYWLAMSNSMYNPII 380
             ||:|::..|:::||::|.|||:||:...:: :.:....:|...|   |::. |..:||..|||:
  Rat   264 -RSERKITLMVMMVVMVFVICWMPFYVVQLV-NVFAEQDDATVSQ---LSVI-LGYANSCANPIL 322

  Fly   381 YCWMNSRFRYGFKMVFRWCL 400
            |.:::..|:..|:.:.  ||
  Rat   323 YGFLSDNFKRSFQRIL--CL 340

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TkR99D	NP_001263092.1	7tmA_TACR	102..392	CDD:320512	84/304 (28%)
		TM helix 1	103..129	CDD:320512	6/25 (24%)
		TM helix 2	136..162	CDD:320512	11/25 (44%)
		TM helix 3	174..204	CDD:320512	10/29 (34%)
		TM helix 4	215..236	CDD:320512	6/20 (30%)
		TM helix 5	269..298	CDD:320512	10/36 (28%)
		TM helix 6	317..347	CDD:320512	12/29 (41%)
		TM helix 7	360..385	CDD:320512	9/24 (38%)
Sstr1	NP_036851.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..50		4/19 (21%)
		7tmA_SSTR1	59..334	CDD:320636	84/304 (28%)
		TM helix 1	60..86	CDD:320636	6/25 (24%)
		TM helix 2	93..119	CDD:320636	11/26 (42%)
		TM helix 3	130..160	CDD:320636	10/29 (34%)
		TM helix 4	172..194	CDD:320636	7/25 (28%)
		TM helix 5	220..249	CDD:320636	8/28 (29%)
		TM helix 6	264..294	CDD:320636	12/30 (40%)
		TM helix 7	302..327	CDD:320636	10/28 (36%)