Protein Alignment TkR99D and Sstr2

DIOPT Version :10

• Sequence 1: NP_001263092.1
• Gene: TkR99D / 43551
• FlyBaseID: FBgn0004622
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_001036071.1
• Gene: Sstr2 / 20606
• MGIID: 98328
• Length: 369
• Species: Mus musculus
• Alignment Length: 359
• Identity: 101/359 - (28%)
• Similarity: 178/359 - (49%)
• Gaps: 62/359 - (17%)

  Fly   102 VLWSILFGGMVIVATG--GNLIVVWIVMTTKRMRTVTNYFIVNLSIADAMVSSLNVTFNYYYMLD 164
            ||..|.|   |:...|  ||.:|:::::...:|:|:||.:|:||:|||.:. .|.:.|....:..
Mouse    45 VLTFIYF---VVCVVGLCGNTLVIYVILRYAKMKTITNIYILNLAIADELF-MLGLPFLAMQVAL 105

  Fly   165 SDWPFGEFYCKLSQFIAMLSICASVFTLMAISIDRYVAIIRPL------QPRMSKRCNLAIAAVI 223
            ..||||:..|::...:..::...|:|.|..:|||||:|::.|:      :||.:|..|:|    :
Mouse   106 VHWPFGKAICRVVMTVDGINQFTSIFCLTVMSIDRYLAVVHPIKSAKWRRPRTAKMINVA----V 166

  Fly   224 WLASTLISCPMMIIYRTEEVPVRGL-SN---RTVCYPEWPDGPTNHSTMESLYNILIIILTYFLP 284
            |..|.|:..|:||        ..|| ||   |:.|...||.   ......:.:.|...||.:.:|
Mouse   167 WCVSLLVILPIMI--------YAGLRSNQWGRSSCTINWPG---ESGAWYTGFIIYAFILGFLVP 220

  Fly   285 IVSMTVTYSRV-------GIELWGSKTIGECTPRQVENVRSKRRVVKMMIVVVLIFAICWLPFHS 342
            :..:.:.|..:       ||.:..||           ..:|:::|.:|:.:||.:|..|||||:
Mouse   221 LTIICLCYLFIIIKVKSSGIRVGSSK-----------RKKSEKKVTRMVSIVVAVFIFCWLPFY- 273

  Fly   343 YFIITSCYPAITEAPFIQELYLAIYWLAMSNSMYNPIIYCWMNSRFRYGFKMVFRWCLFVRVGTE 407
            .|.::|...||:..|.::.::..:..|..:||..|||:|.:::..|:..|:.|.  ||....|||
Mouse   274 IFNVSSVSVAISPTPALKGMFDFVVILTYANSCANPILYAFLSDNFKKSFQNVL--CLVKVSGTE 336

  Fly   408 PFSRRENLTSRYSCSGSPDHNRI-KRNDTQKSIL 440
            ...|.::         ..|.:|: :..:||:::|
Mouse   337 DGERSDS---------KQDKSRLNETTETQRTLL 361

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TkR99D	NP_001263092.1	7tmA_TACR	102..392	CDD:320512	88/308 (29%)
		TM helix 1	103..129	CDD:320512	8/27 (30%)
		TM helix 2	136..162	CDD:320512	10/25 (40%)
		TM helix 3	174..204	CDD:320512	10/29 (34%)
		TM helix 4	215..236	CDD:320512	6/20 (30%)
		TM helix 5	269..298	CDD:320512	6/35 (17%)
		TM helix 6	317..347	CDD:320512	12/29 (41%)
		TM helix 7	360..385	CDD:320512	7/24 (29%)
Sstr2	NP_001036071.1	7tmA_SSTR2	44..323	CDD:320637	88/308 (29%)
		TM helix 1	45..71	CDD:320637	9/28 (32%)
		TM helix 2	78..104	CDD:320637	10/26 (38%)
		TM helix 3	115..145	CDD:320637	10/29 (34%)
		TM helix 4	157..179	CDD:320637	8/25 (32%)
		TM helix 5	205..234	CDD:320637	5/28 (18%)
		TM helix 6	249..279	CDD:320637	12/30 (40%)
		TM helix 7	291..316	CDD:320637	7/24 (29%)