Protein Alignment TkR99D and npr-7

DIOPT Version :10

• Sequence 1: NP_001263092.1
• Gene: TkR99D / 43551
• FlyBaseID: FBgn0004622
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_509570.3
• Gene: npr-7 / 185321
• WormBaseID: WBGene00018067
• Length: 380
• Species: Caenorhabditis elegans
• Alignment Length: 387
• Identity: 95/387 - (24%)
• Similarity: 170/387 - (43%)
• Gaps: 65/387 - (16%)

  Fly   107 LFGGMVIVATGGNLIVVWIVMTTKRMRTVTNYFIVNLSIADAMVSSLNV---TFNYYYMLDSDWP 168
            |.|.:.:|   |||.|:.||:..:.|:||||.||.::|.||.:::|.::   ...||..:   |.
 Worm    33 LVGALSLV---GNLAVLLIVICRREMQTVTNIFISSVSAADLVITSFSLWATPLAYYQRV---WH 91

  Fly   169 FGEFYCKLSQFIAMLSICASVFTLMAISIDRYVAIIRPLQPRMSKRCNLAIAAVIWLASTLISCP 233
            ||::.|.:...|..||:.....||.|:::|||..:..|.:..|||:..|.|.|.||:....:..|
 Worm    92 FGKYMCYMVSIIQGLSLMWVPLTLAAVALDRYSLVASPFRQPMSKKTCLLIIAGIWMGGFAVLSP 156

  Fly   234 M--MIIYRTEEVPVRGLSNRTVCYPEWPDGPTNHSTMESLYNILIIILTYFLPIVSMTVTYSRVG 296
            |  |:.:.....|..      .|...| |....|..:  .|.:.::::...:|:|.:::.:.|:.
 Worm   157 MIRMVDFVDSYGPCH------FCLESW-DHDKQHYRL--FYGLSVLVIRSAIPLVLISLCHWRIA 212

  Fly   297 I----------ELWGSKTIGECTPRQVENVRSKRRVVKMMIVVVLIFAICWLPFHSYFIITSCYP 351
            :          .|..:.|:.:.|     ::|.|:|:..:::.:|:|||:..||.....::.....
 Worm   213 VILNTQTKKFQTLRSASTVTQST-----DIRRKQRLQTLLLAMVVIFAVSSLPLDLSNVLQDLIV 272

  Fly   352 AITEAPFIQE----LYLAIYWLAMSNSMYNPIIYCWMNSRFRYGFKMVFRWCLFVRVGTEPFSRR 412
            .....|....    ::...:|.||:.::.||::|.:.|..||    ...:.|.....|...|.|
 Worm   273 VYQVRPVPDNVRHFIFFFCHWTAMAGTLLNPLVYAYYNENFR----RQIQTCFGEMRGQGEFKR- 332

  Fly   413 ENLTSRYS-CSGSPDHNRIKRNDTQKSILYTCPSSPKSHR------ISHSGTGRSATLRNSL 467
                ..|| .||...:....|.|.:::          .||      ::::.||....||..|
 Worm   333 ----GLYSIVSGRYSYRETFRADDEEN----------HHRQNTRIELANNQTGDIEVLRTDL 380

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TkR99D	NP_001263092.1	7tmA_TACR	102..392	CDD:320512	78/303 (26%)
		TM helix 1	103..129	CDD:320512	9/21 (43%)
		TM helix 2	136..162	CDD:320512	10/28 (36%)
		TM helix 3	174..204	CDD:320512	10/29 (34%)
		TM helix 4	215..236	CDD:320512	7/22 (32%)
		TM helix 5	269..298	CDD:320512	4/38 (11%)
		TM helix 6	317..347	CDD:320512	9/29 (31%)
		TM helix 7	360..385	CDD:320512	6/28 (21%)
npr-7	NP_509570.3	7tmA_NPYR-like	25..317	CDD:320331	78/307 (25%)
		TM helix 1	26..52	CDD:320331	9/21 (43%)
		TM helix 2	59..84	CDD:320331	8/24 (33%)
		TM helix 3	97..127	CDD:320331	10/29 (34%)
		TM helix 4	138..159	CDD:320331	7/20 (35%)
		TM helix 5	185..214	CDD:320331	4/30 (13%)
		TM helix 6	238..268	CDD:320331	9/29 (31%)
		TM helix 7	285..310	CDD:320331	6/24 (25%)