Protein Alignment TkR99D and npr-33

DIOPT Version :10

• Sequence 1: NP_001263092.1
• Gene: TkR99D / 43551
• FlyBaseID: FBgn0004622
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_510612.1
• Gene: npr-33 / 185141
• WormBaseID: WBGene00009278
• Length: 399
• Species: Caenorhabditis elegans
• Alignment Length: 367
• Identity: 91/367 - (24%)
• Similarity: 171/367 - (46%)
• Gaps: 58/367 - (15%)

  Fly   103 LWSILFG--GMVIVATG--GNLIVVWIV-MTTKRMRTVTNYFIVNLSIADAMVSSLNVTF----N 158
            |:.|:||  .|:|:..|  ||:.:|::: |..|.|.:..|.|::||:|||..    |:.|    .
 Worm    57 LYFIVFGLVFMIIICAGVIGNIFIVFVILMDRKLMSSSVNQFLLNLAIADLG----NLIFCSPDA 117

  Fly   159 YYYMLDSDWPFGEFYCKLSQFIAMLSICASVFTLMAISIDRYVAIIRPLQ-PRMSKRCNLAIAAV 222
            ...::|..|....|.|.|.:|:....:.|||...|||.::|::||..|:: .|.|.:..:::.|.
 Worm   118 ILVLIDRGWLLPNFACHLLRFLQEYFLYASVLLQMAIGVERFLAICSPMRMQRFSTKTTISVLAG 182

  Fly   223 IWLASTLISCPM-----MIIYRTEEVPVRGLSNRTVCYPEWPDGPTNHSTMESLYNILIIILTYF 282
            :|..:...:.|.     ::.::......:|:|::|..|                :....:|:.|.
 Worm   183 VWCVAACFASPYFLYQGIVFHKLYFCFWKGISHKTRTY----------------FKYCELIVLYA 231

  Fly   283 LPIVSMTVTYSRVGIELWGSKTIGECT--PRQVENVRSKRRVVKMMIVVVLIFAICWLPFHSYFI 345
            :|:|.:|..||.:...|||::......  .:|...::.:|.||||:|:.:|::.:|:.|....|:
 Worm   232 IPLVFLTTLYSIMCRVLWGNEDNHNIANHSQQEAILKLRRSVVKMLIISMLLYFLCYTPIQVLFM 296

  Fly   346 ITSCYPAITEAPFIQELYLAIYWLAMSNSMYNPIIY--CWMNSRFRY-----GFKMVFRWCLFVR 403
            :........:.|  |.|.|.:..|::.:|..|||:|  |..:.|.|.     |......|.|
 Worm   297 LEKILDHSVQLP--QWLRLLLNVLSVMSSSTNPIVYIICCRHFRLRLRDVAAGISSFCCWLL--- 356

  Fly   404 VGTEPFSRR------ENLTSRYSCSGSPDHNRIKRNDTQKSI 439
               ..||:.      |::|::.|.|........:|.:::.::
 Worm   357 ---PSFSKSEYECVDESMTAKLSRSPYVSFRSSRRQNSRANL 395

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TkR99D	NP_001263092.1	7tmA_TACR	102..392	CDD:320512	81/312 (26%)
		TM helix 1	103..129	CDD:320512	11/30 (37%)
		TM helix 2	136..162	CDD:320512	9/29 (31%)
		TM helix 3	174..204	CDD:320512	11/29 (38%)
		TM helix 4	215..236	CDD:320512	3/25 (12%)
		TM helix 5	269..298	CDD:320512	7/28 (25%)
		TM helix 6	317..347	CDD:320512	10/29 (34%)
		TM helix 7	360..385	CDD:320512	10/26 (38%)
npr-33	NP_510612.1	7tm_classA_rhodopsin-like	62..334	CDD:410626	76/293 (26%)
		TM helix 1	62..87	CDD:410626	8/24 (33%)
		TM helix 2	94..121	CDD:410626	9/30 (30%)
		TM helix 3	133..163	CDD:410626	11/29 (38%)
		TM helix 4	175..194	CDD:410626	2/18 (11%)
		TM helix 5	218..243	CDD:410626	7/40 (18%)
		TM helix 6	268..298	CDD:410626	10/29 (34%)
		TM helix 7	309..334	CDD:410626	9/24 (38%)