Protein Alignment TkR99D and Galr2

DIOPT Version :10

• Sequence 1: NP_001263092.1
• Gene: TkR99D / 43551
• FlyBaseID: FBgn0004622
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_034384.3
• Gene: Galr2 / 14428
• MGIID: 1337018
• Length: 371
• Species: Mus musculus
• Alignment Length: 339
• Identity: 105/339 - (30%)
• Similarity: 170/339 - (50%)
• Gaps: 53/339 - (15%)

  Fly    74 GDVEDAAEDAAASMETGSFAFVVPWWR--QVLWSILFGGMVIVATGGNLIVVWIVMTTKRMRTVT 136
            |.....|||  :|.|.|.      .|:  .||..:.|..:.:|...||.:|:.:::...:..:.|
Mouse     3 GSDSQGAED--SSQEGGG------GWQPEAVLVPLFFALIFLVGAVGNALVLAVLLRGGQAVSTT 59

  Fly   137 NYFIVNLSIADAMVSSLNVTFN-YYYMLDSDWPFGEFYCKLSQFIAMLSICASVFTLMAISIDRY 200
            |.||:||.:||.......|.|. ..|.|| ||.||...||...|:..|::.||.|||.|:|:|||
Mouse    60 NLFILNLGVADLCFILCCVPFQATIYTLD-DWVFGSLLCKAVHFLIFLTMHASSFTLAAVSLDRY 123

  Fly   201 VAIIRPLQPRMSKRCNLAIAAV--IWLASTLISCPMMIIYRTEEVPVRGLSNRTVCYPEWPDGPT 263
            :||..||..|..:....|:||:  ||..:.|.|.|.:..|...:     |:|.|||:|.| ..|.
Mouse   124 LAIRYPLHSRELRTPRNALAAIGLIWGLALLFSGPYLSYYSQSQ-----LANLTVCHPAW-SAPR 182

  Fly   264 NHSTMESLYNILIIILTYFLPIVSMTVTYSRVGIELWGSKTIGECTPRQVENV-------RSKRR 321
            ..:     .::...:.:|.||::.:::||:|....||          |.|:.|       |:||:
Mouse   183 RRA-----MDLCTFVFSYLLPVLVLSLTYARTLHYLW----------RTVDPVAAGSGSQRAKRK 232

  Fly   322 VVKMMIVVVLIFAICWLPFHSYFIITSC-----YPAITEAPFIQELYLAIYWLAMSNSMYNPIIY 381
            |.:|:::|.::|.:||:|.|:..:   |     :| :|.|.:  .|.:..:.::.:||..|||:|
Mouse   233 VTRMIVIVAVLFCLCWMPHHALIL---CVWFGRFP-LTRATY--ALRILSHLVSYANSCVNPIVY 291

  Fly   382 CWMNSRFRYGFKMV 395
            ..::..||.||:.:
Mouse   292 ALVSKHFRKGFRKI 305

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TkR99D	NP_001263092.1	7tmA_TACR	102..392	CDD:320512	95/304 (31%)
		TM helix 1	103..129	CDD:320512	6/25 (24%)
		TM helix 2	136..162	CDD:320512	10/26 (38%)
		TM helix 3	174..204	CDD:320512	15/29 (52%)
		TM helix 4	215..236	CDD:320512	8/22 (36%)
		TM helix 5	269..298	CDD:320512	6/28 (21%)
		TM helix 6	317..347	CDD:320512	11/29 (38%)
		TM helix 7	360..385	CDD:320512	7/24 (29%)
Galr2	NP_034384.3	7tmA_Gal2_Gal3_R	25..302	CDD:320225	95/304 (31%)
		TM helix 1	26..52	CDD:320225	6/25 (24%)
		TM helix 2	59..85	CDD:320225	10/25 (40%)
		TM helix 3	97..127	CDD:320225	15/29 (52%)
		TM helix 4	139..159	CDD:320225	7/19 (37%)
		TM helix 5	183..212	CDD:320225	6/33 (18%)
		TM helix 6	228..258	CDD:320225	11/32 (34%)
		TM helix 7	270..295	CDD:320225	7/26 (27%)