Protein Alignment TkR99D and Galr1

DIOPT Version :10

• Sequence 1: NP_001263092.1
• Gene: TkR99D / 43551
• FlyBaseID: FBgn0004622
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_032108.1
• Gene: Galr1 / 14427
• MGIID: 1096364
• Length: 348
• Species: Mus musculus
• Alignment Length: 363
• Identity: 101/363 - (27%)
• Similarity: 170/363 - (46%)
• Gaps: 71/363 - (19%)

  Fly   106 ILFGGMVIVATGGNLIVVWIVMTTK--RMRTVTNYFIVNLSIADAMVSSLNVTFNYYYMLDSDWP 168
            ::||.:..:...||.:|:.::..:|  :.|:.||.||:||||||.......:.|.........|.
Mouse    38 VVFGLIFAMGVLGNSLVITVLARSKPGKPRSTTNLFILNLSIADLAYLLFCIPFQATVYALPTWV 102

  Fly   169 FGEFYCKLSQFIAMLSICASVFTLMAISIDRYVAII---RPLQPRMSKRCNLAIAAVIWLASTLI 230
            .|.|.||...:...:|:..|:|||.|:|:||||||:   |....|:|:...|.: ..||..|..:
Mouse   103 LGAFICKFIHYFFTVSMLVSIFTLAAMSVDRYVAIVHSRRSSSLRVSRNALLGV-GFIWALSIAM 166

  Fly   231 SCPM----MIIYRTEEVPVRGLSNRTVCYPEWPDGPTNHSTMESLYNILIIILTYFLPIVSMTVT 291
            :.|:    .:.:|.        ||:|.|:.:||     :...:..|.:...:..|.||::.:...
Mouse   167 ASPVAYHQRLFHRD--------SNQTFCWEQWP-----NKLHKKAYVVCTFVFGYLLPLLLICFC 218

  Fly   292 YSRVGIELWGSKTIGECTPRQVENV-----RSKRRVVKMMIVVVLIFAICWLPFHSYFIIT--SC 349
            |::|...|          .::::|:     .||::..:.::|||::|.|.|||.|...:..  ..
Mouse   219 YAKVLNHL----------HKKLKNMSKKSEASKKKTAQTVLVVVVVFGISWLPHHVVHLWAEFGA 273

  Fly   350 YPAITEAPFIQELYLAIYWLAMSNSMYNPIIYCWMNSRFRYGFKMVFRWCLFVRVGTEPFSRREN 414
            :| :|.|.|.  ..:..:.||.|||..|||||.:::..||..:|.||: |
Mouse   274 FP-LTPASFF--FRITAHCLAYSNSSVNPIIYAFLSENFRKAYKQVFK-C--------------- 319

  Fly   415 LTSRYSCSGSPDHNRIKRNDTQ--KSILYTCPSSPKSH 450
                :.|..||      |::|:  ||.:.|.||:..:|
Mouse   320 ----HVCDESP------RSETKENKSRMDTPPSTNCTH 347

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TkR99D	NP_001263092.1	7tmA_TACR	102..392	CDD:320512	86/301 (29%)
		TM helix 1	103..129	CDD:320512	5/22 (23%)
		TM helix 2	136..162	CDD:320512	11/25 (44%)
		TM helix 3	174..204	CDD:320512	14/29 (48%)
		TM helix 4	215..236	CDD:320512	5/24 (21%)
		TM helix 5	269..298	CDD:320512	6/28 (21%)
		TM helix 6	317..347	CDD:320512	11/29 (38%)
		TM helix 7	360..385	CDD:320512	10/24 (42%)
Galr1	NP_032108.1	7tmA_Gal1_R	34..313	CDD:320226	86/301 (29%)
		TM helix 1	35..61	CDD:320226	5/22 (23%)
		TM helix 2	70..96	CDD:320226	11/25 (44%)
		TM helix 3	108..138	CDD:320226	14/29 (48%)
		TM helix 4	150..170	CDD:320226	4/20 (20%)
		TM helix 5	196..225	CDD:320226	6/28 (21%)
		TM helix 6	239..269	CDD:320226	11/29 (38%)
		TM helix 7	281..306	CDD:320226	11/26 (42%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	328..348		7/20 (35%)