Protein Alignment TkR99D and npy2r

DIOPT Version :10

• Sequence 1: NP_001263092.1
• Gene: TkR99D / 43551
• FlyBaseID: FBgn0004622
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: XP_004911210.1
• Gene: npy2r / 100498351
• XenbaseID: XB-GENE-983413
• Length: 408
• Species: Xenopus tropicalis
• Alignment Length: 338
• Identity: 94/338 - (27%)
• Similarity: 173/338 - (51%)
• Gaps: 23/338 - (6%)

  Fly    77 EDAAEDAAASMETGSFA--FVVPW---------------WRQVLWSILFGGMVIVATGGNLIVVW 124
            |:..||....|.|..:|  ...|:               ..||:..:.:..::::...||.:|::
 Frog    32 ENRTEDIKTEMNTWFYAAGLTTPYNDLTKPELIDITKLLSVQVVLILAYSSIILLGVLGNSLVIY 96

  Fly   125 IVMTTKRMRTVTNYFIVNLSIADAMVSSLNVTFNYYYMLDSDWPFGEFYCKLSQFIAMLSICASV 189
            :|:..|.||||||:|||||:::|.||::|.:.|...|.|..||.||...|.|..:...|::..|.
 Frog    97 VVIKFKTMRTVTNFFIVNLAVSDLMVNTLCLPFTLVYTLLDDWKFGTVLCHLVTYSQGLAVQVST 161

  Fly   190 FTLMAISIDRYVAIIRPLQPRMSKRCNLAIAAVIWLASTLISCPMMIIYRTEEVPVRGLSNRTVC 254
            .|||.|::||:..|:..|:.::|.:....|..:.|:.|.|::.|:.|......:.:........|
 Frog   162 VTLMVIALDRHRCIVYHLESKISTKICFMIIGITWVCSALLASPLAIFKEYSVIVISSDFQIQAC 226

  Fly   255 YPEWPDGPTNHSTMESLYNILIIILTYFLPIVSMTVTYSRVGIELWGSKTIGECTPRQVENVRSK 319
            ...||.|..|:.|   :|:|.::::.|.:|:..::..|.|:..:|....:.|.......:.   :
 Frog   227 SERWPVGDLNYGT---IYSISMLLIQYIVPLAIISYAYIRIWTKLKNHVSPGGGNDHYHQR---R 285

  Fly   320 RRVVKMMIVVVLIFAICWLPFHSYFIITSCYPAITEAPFIQELYLAIYWLAMSNSMYNPIIYCWM 384
            |:..||::.||::||:||||||::.:.:.....:.:....:.:|...:.:||.::..||::|.||
 Frog   286 RKTTKMLVAVVVVFAVCWLPFHAFQLASDIDGKVLDLNEYKLIYTIFHVIAMCSTFANPLLYGWM 350

  Fly   385 NSRFRYGFKMVFR 397
            |:.:|..|...|:
 Frog   351 NNNYRTAFLTAFK 363

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TkR99D	NP_001263092.1	7tmA_TACR	102..392	CDD:320512	84/289 (29%)
		TM helix 1	103..129	CDD:320512	4/25 (16%)
		TM helix 2	136..162	CDD:320512	12/25 (48%)
		TM helix 3	174..204	CDD:320512	10/29 (34%)
		TM helix 4	215..236	CDD:320512	5/20 (25%)
		TM helix 5	269..298	CDD:320512	6/28 (21%)
		TM helix 6	317..347	CDD:320512	13/29 (45%)
		TM helix 7	360..385	CDD:320512	7/24 (29%)
npy2r	XP_004911210.1	7tmA_NPY2R	74..358	CDD:320521	84/289 (29%)
		TM helix 1	75..101	CDD:320521	4/25 (16%)
		TM helix 2	108..133	CDD:320521	12/24 (50%)
		TM helix 3	146..176	CDD:320521	10/29 (34%)
		TM helix 4	187..208	CDD:320521	5/20 (25%)
		TM helix 5	238..267	CDD:320521	7/31 (23%)
		TM helix 6	283..313	CDD:320521	13/32 (41%)
		TM helix 7	326..351	CDD:320521	7/24 (29%)